Latest updates for Neurodegeneration

Fresh curated links around neurodegeneration are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • Calcineurin/NFAT Pathway Links Calcium Stress to Neurodegeneration Timing
  • New Form of Cell Death Discovered in Alzheimer’s
  • Long-Term Iron Accumulation Strips Neurons of Disease Resilience

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bioengineer.org /4 days ago

Calcineurin/NFAT Pathway Links Calcium Stress to Neurodegeneration Timing

Neurodegenerative diseases remain one of the most daunting challenges in modern medicine, with their complex etiologies and often irreversible progression. A new study published in...

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neurosciencenews.com /2 weeks ago

New Form of Cell Death Discovered in Alzheimer’s

Researchers identified a new form of programmed cell death called karyoptosis, driven by the interaction of p38 MAP kinase and LaminB1, which causes nuclear disintegration in 35% o...

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neurosciencenews.com /2 weeks ago

Long-Term Iron Accumulation Strips Neurons of Disease Resilience

Researchers defined "chronoferroptosis," a progressive, time-dependent iron accumulation pathway that systematically depletes antioxidant defenses and strips aging neurons of their...

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genengnews.com /2 weeks ago

Iron Accumulation Drives Neurodegeneration via Chronic Stress Pathway

Iron accumulation is a key target in the effort to predict, prevent, and treat neurodegenerative diseases. A new stress pathway is a promising therapeutic route for boosting neuron...

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lifespan.io /1 month ago

Neurons’ Protein Disposal Trick Offers Alzheimer’s Insights

According to a new study, a special protein disposal system, currently found only in neurons, is linked to central hallmarks of Alzheimer’s disease [1]. The membranal proteasome Al...

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neurosciencenews.com /6 days ago

Loss of TDP-43 Strips Microglia of Their Brain-Cleaning Power

The TDP-43 protein is an essential regulator of microglial housekeeping in the developing brain.

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braingle.com /2 weeks ago

Neurogenesis

Neurogenesis is the process by which new neurons are created in the brain. A common myth is that adults are losing some number of neurons every second and that there is nothing we...

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organicconsumers.org /3 weeks ago

Long-Term Iron Accumulation Strips Neurons of Disease Resilience

June 25, 2023 | Source: Neuroscience News Summary: Neurodegenerative conditions like Alzheimer’s and Parkinson’s diseases afflict tens of millions of people worldwide, driven by a...

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rna-seqblog.com /1 month ago

‘Garbage collectors’ of the brain grind to a halt in fatal disease

RNA sequencing revealed dysfunctional microglia in multiple system atrophy, providing new insight into immune exhaustion and potential therapeutic targets in this aggressive neurod...

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neurosciencenews.com /1 month ago

Gene Therapy Proven to Shield Brain from TDP-43 Damage

An experimental gene therapy called SynCav1 can protect the central nervous system from the cognitive decline linked to TDP-43-related proteinopathy, a primary driver of FTD, ALS,...

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labiotech.eu /1 month ago

Beyond amyloid and dopamine: emerging technologies reshaping neurology 

Find out about some early-stage technologies in neurology that aim to go beyond amyloid, dopamine, and what has dominated the field. The post Beyond amyloid and dopamine: emerging...

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medicalxpress.com /1 month ago

Creating mini-brains from stem cells reveals a new, promising treatment for a devastating childhood disease

Variants in the DHDDS gene cause a severe neurodegenerative condition, characterized by tremors, seizures, coordination and learning difficulties, usually manifesting in early chil...

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fightaging.org /1 month ago

Cellular Senescence in Microglia as a Contribution to Neurodegenerative Conditions

Increasing attention in the research community is being given to age-related dysfunction of microglia in the brain as a contribution to loss of cognitive function and onset and pro...

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bioengineer.org /1 month ago

Caspase-4 Mice Show Cytoplasmic TDP-43, Aging Neuropathy

In a groundbreaking study poised to redefine our understanding of neurodegenerative diseases, researchers have uncovered compelling evidence linking the expression of caspase-4 wit...

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neurosciencenews.com /3 days ago

Decreasing Productivity Can Precede a Dementia Diagnosis by Years

A new study demonstrates that early-onset dementia is associated with severe work productivity losses up to 15 years before a formal diagnosis.

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fightaging.org /1 week ago

Arc is Involved in Transmission of Tau Between Neurons in Alzheimer's Disease

The more severe later stages of Alzheimer's disease are characterized by altered forms of tau protein aggregating inside neurons to cause dysfunction, inflammation, and cell death....

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neurosciencenews.com /1 month ago

Charting 54,583 Connectomes to Detect Brain Disease

The global framework validates the "last in, first out" theory of brain aging while revealing that individuals sharing the same clinical diagnosis exhibit completely unique microst...

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fightaging.org /1 month ago

GRK2 Aggregation as a Cause of Mitochondrial Dysfunction in Alzheimer's Disease

Here researchers report on a novel form of pathological protein aggregation in the aging brain and evidence for it to contribute to mitochondrial dysfunction in Alzheimer's disease...

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neurosciencenews.com /3 weeks ago

Lipid Molecule Slows Progressive Retinal Degeneration

Restoring the lipid molecule erucamide via silicon nanoparticles activates retinal myeloid cells via the TMEM19 protein, stabilizing the neurovascular unit and significantly slowin...

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fightaging.org /2 days ago

Extracellular Vesicles Link Inflammation in the Body to Accelerated Neurodegeneration in the Brain

STING is a master regulator of inflammatory signaling, triggered by a range of different sensor proteins for foreign material or forms of damage within a cell. With age, these sens...

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fightaging.org /1 month ago

Caveolin-1 Gene Therapy Reduces TDP-43 Related Neurodegeneration in a Mouse Model

You might recall that gene therapy to overexpress caveolin-1 in the brain was recently shown to reduce pathology in a mouse model of Alzheimer's disease. In today's open access pap...

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bioengineer.org /1 month ago

Brain Maintenance Biomarkers in Aging and Neurodegeneration

In the relentless quest to unravel the complexities of brain aging and neurodegenerative diseases, a groundbreaking study led by Li, Zhang, Li, and colleagues, published in Nature...

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neurosciencenews.com /6 days ago

NFL Players Face Fourfold Increase in Neurodegenerative Mortality

A retrospective cohort study of 19,824 NFL players confirms that professional football veterans face a fourfold increase in neurodegenerative mortality, including a 3.8-fold surge...

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lifespan.io /1 month ago

Fighting Parkinson’s by Restoring Protein Degradation

Researchers have explained how a protein found in both yeast and humans facilitates the destruction of the core protein responsible for Parkinson’s […]

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Sources covering Neurodegeneration

feeds.braingle.com

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bioengineer.org

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feeds.feedburner.com

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medicalxpress.com

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neurosciencenews.com

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fightaging.org

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