Latest updates for Alpha-Synuclein

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Recent items include:

  • α-Synuclein curbs glioma growth via CDH13–JNK/c-Jun signaling pathway
  • Beyond amyloid and tau: A perspective on the impact of α-synuclein in Alzheimer’s disease
  • Different Parts of the Brain Exhibit Different Vulnerability to Synucleinopathy

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bioengineer.org /1 month ago

α-Synuclein curbs glioma growth via CDH13–JNK/c-Jun signaling pathway

In a finding that could reshape how scientists think about one of medicine’s most stubborn brain cancers, researchers in China have discovered that α-synuclein—the protein most fam...

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neurology.ufl.edu /1 day ago

Beyond amyloid and tau: A perspective on the impact of α-synuclein in Alzheimer’s disease

Another new publication! Congratulations Dr. Abbas Babajani-Feremi on the publication of “Beyond amyloid and tau: A perspective on the impact of α-synuclein in Alzheimer’s disease,...

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fightaging.org /1 month ago

Different Parts of the Brain Exhibit Different Vulnerability to Synucleinopathy

Parkinson's disease and Lewy body dementia are synucleinopathies, characterized by the spread of misfolded α-synuclein through the central nervous system. The presence of misfolded...

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bioengineer.org /2 weeks ago

Hidden Brain Cells Called Oligodendrocytes Emerge as Unexpected Drivers of Parkinson’s Disease

A spatial multi-omics study in Nature Communications identifies disease-associated oligodendrocytes whose interleukin 33–ST2 signaling influences alpha-synuclein burden and motor s...

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bioengineer.org /2 weeks ago

Beyond ALS: Misfolded SOD1 Emerges as a Shared Player in Brain Disease

A sweeping review of human neuropathological evidence shows that misfolded SOD1, long tied to familial ALS, coexists with TDP-43, tau, alpha-synuclein, and amyloid-beta across mult...

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fightaging.org /1 month ago

The State of Development for Therapies to Treat Tauopathies

The major neurodegenerative conditions are characterized by pathology deriving from a small number of misfolded or otherwise altered proteins. Amyloid-β misfolding and aggregation...

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bioengineer.org /1 week ago

Mitochondrial protein CHCHD2 emerges as a guardian of the aging brain

New research shows that the age-related decline of the mitochondrial protein CHCHD2 disrupts the mitochondria-lysosome axis and drives proteostatic collapse in Lewy body disorders,...

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parkinsonsnewstoday.com /3 weeks ago

$3M federal grant will allow study of protein causing Parkinson’s dementia

A team at Colorado State University (CSU) has been awarded $3 million from the National Institutes of Health (NIH) to investigate how a distinct variant of the alpha-synuclein prot...

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neurology.ufl.edu /2 weeks ago

Complementary biomarkers or conflicting signals? DaT SPECT and synuclein skin biopsy in parkinsonian syndromes

New research in Parkinsons Diesease! Congratulations to Drs. A. Enrique Martinez-Nunez, Nur Walker-Pizarro, Aparna Wagle Shukla, Adolfo Ramirez-Zamora, and Nikolaus R. McFarland on...

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Sources covering Alpha-Synuclein

bioengineer.org

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neurology.ufl.edu

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parkinsonsnewstoday.com

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fightaging.org

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