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A light-induced detection method rapidly measures tiny amounts of the colorectal cancer biomarker CEACAM-5 in blood plasma, revealing that it forms nanoscale aggregates.
‘Ome is where the Wound is: Biomarkers of Healing in Chronic Diabetic Foot Ulcers Marc Glucksman et al April 2017; The FASEB Journal; vol. 31 no. 1 Supplement 780.14 Of...
Researchers identified candidate biomarkers in spinal fluid and blood that showed different patterns among healthy controls, people in a prodromal group at risk of Parkinson’s, and...
Biomarkers that reflect the brain’s workings have been difficult to pin down in neurology studies, but the field has come a long way. The post Changing with the times: what is the...
A large prospective UK Biobank study of 52,584 adults identified nine plasma proteins, led by neurofilament light chain, that predict ALS onset up to a decade before symptoms, with...
Neurofilament assay is used as a marker of nerve damage or inflammation induced nerve damage/inflammatory activity, and the people doing these assays have been part of a biomarker...
Researchers have discovered key biomarkers that are strongly linked to all-cause mortality and identified four measurements with independent predictive power. Biological versus chr...
AcademyHealth Releases Compendium of Cancer Biomarker Initiatives: A Central Repository for Cancer Biomarker Testing Resources AcademyHealth’s Scaling Cancer Biomarker Test...
Blood levels of three biomarkers — clusterin (CLU), neurofilament light chain (NfL), and low-density lipoprotein cholesterol (LDL-C) — may help identify cognitive impairment and as...
The fluid surrounding the brain may hold another clue to Alzheimer’s, with elevated levels of an enzyme called meprin-β raising the possibility of a new disease indicator. One of t...
An experimental blood test could help detect early pancreatic cancer and precancerous changes, guiding decisions about further testing. People at high risk of pancreatic cancer are...
A two-case report found that characteristic CT findings, markedly elevated NSE and multidisciplinary review enabled an image-supported small cell lung cancer diagnosis and treatmen...
Obesity has become one of the most consequential public health challenges of the modern era, driving elevated risks of type 2 diabetes, cardiovascular disease, and a constellation...
Alzheimer’s disease is usually imagined as a disease of old age. The biology behind it can begin much earlier, potentially years or decades before memory problems become obvious. A...
Multiple myeloma, an incurable cancer of the bone marrow’s plasma cells, has long defied doctors’ attempts to predict its course. Patients with what looks like the same disease can...
A new study from Suzhou shows that the lung glycoprotein KL-6, shed by damaged type II alveolar epithelial cells, can distinguish severe from mild Chlamydia pneumoniae infection in...
Blood tests to assess Alzheimer's disease risk and progression exist, for example based on the presence of circulating varieties of tau protein, but there is a great deal of room f...
AcademyHealth Releases Strategic Roadmap for Advancing Cancer Biomarker Testing at Scale For patients facing uncertainty or fear around a cancer diagnosis, cancer biomarker...
An important goal in the research community is to build a robust measure of biological age, the burden of age-related damage and dysfunction contributing to disease and mortality,...
by Alejandra Paja-García, Rafael Romero-Becerra, Tero Aittokallio, Alberto López Pancreatic ductal adenocarcinoma (PDAC), with a 12% 5-year survival rate, is the most aggressive t...
Researchers built a four-gene signature based on propionate metabolism that stratifies colorectal cancer patients by survival risk and links tumor metabolism to immune features and...
Scientists have discovered that aging immune cells may hold a hidden blood-based clue to detecting depression. Scientists have discovered that the biological aging of certain white...
by Hailing Ou, Jinli Miao, Fusheng Ling, Jie Gao, Tingan Wang, Zhihua Ye, Chunbo Zhang, Mingwei Huang, Yuzhou Qin Screening for gastric cancer (GC) is critical for improving patie...
RGCB team designs ‘self-assembling dual-diameter’ nanopore sensors that are capable of detecting biomarkers linked to neurodegenerative diseases with high sensitivity
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