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5,812 protein groups were quantified in postmenopausal ovaries, uncovering molecular shifts associated with inflammation, immunity, and extracellular matrix remodeling. The post Pr...
The results of a large prospective proteomic study have associated proteins linked with the immune system, cell adhesion, blood vessel formation, and known prostate cancer genes, t...
Blood plasma is often described as the most information-rich liquid in the human body, a fluid that carries molecular echoes of nearly every organ and every disease process unfoldi...
A new catalog of 1,122 mitochondrial proteins reveals how Acanthamoeba adapts to oxygen loss—and may highlight possible targets for treating sight-threatening infections. The post...
Novel approaches are urgently needed to improve availability of diagnostic assays, and recent efforts have shifted toward uncovering the biological pathways and molecular profiles...
A more coherent approach: a peptide-mapping LC-HRMS (liquid chromatography-high resolution mass spectrometry) workflow that can identify and monitor multiple product quality attrib...
Every process that keeps a plant alive—from the immune responses that fend off pathogens to the signaling cascades that help roots find water—depends on proteins physically tou...
Multiomics analysis combines data from two or more omics layers—such as genomics, transcriptomics, proteomics, and epigenomics. However, published criticisms of multiomics approach...
With no cure available for prion diseases, researchers are striving to improve assay sensitivity and exploit the benefits of real-time monitoring to support the development of bett...
Despite advances in other proteomic methods, including mass spectrometry, western blotting remains one of the most widely-used techniques across life sciences research due to its a...
High-throughput proteomics combined with AI-based structural modeling helped researchers discover molecular glues that degrade VAV1. The approach could support new therapies for bl...
Built from transcriptomic and mass spectrometry data, the atlas uncovered more than 1,000 previously uncharacterized microproteins and pointed to a potential connection between one...
Why does a ribeye taste different from a rump even when both come from the same animal, raised on the same farm and slaughtered on the same day? A new multi-omics study of Pinglian...
The first comprehensive proteomic analysis of retinas from humanized sickle cell anemia mice reveals early downregulation of phototransduction and mitochondrial energy pathways, po...
A recent collaboration between Kent scientists and the Science and Technology Facilities Council-supported Central Laser Facility (CLF), has affirmed the remarkable versatility of...
A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of com...
ARCADIA integrates single-cell RNA sequencing with spatial proteomics to reveal how tissue neighborhoods influence B-cell maturation, T-cell activation, and other transcriptional p...
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