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FRIDAY, April 24, 2026 — Psilocybin, the active ingredient in magic mushrooms, is moving into the mainstream. As states move toward decriminalization and the public grows more curi...
Low doses of psilocybin made aggressive fish calmer without stopping social interaction, revealing a selective effect on escalated conflict behaviors. More than 200 mushroom specie...
A groundbreaking study by researchers at the University of California, San Francisco (UCSF), in collaboration with Imperial College London, has unveiled compelling evidence that a...
Amid a renaissance in the science of psychedelics, public interest in psilocybin – or magic mushrooms, as they’ve long been known – is surging.
Researchers discovered that psilocybin temporarily increases brain complexity and may reshape neural connections for weeks. Researchers at UC San Francisco and Imperial College Lon...
MONDAY, May 18, 2026 — Just a single dose of psilocybin can provide rapid relief from depression, a new small-scale clinical trial has shown. Within a week, people treated with one...
Psilocybin, LSD, mescaline, DMT, and ayahuasca have different chemical structures, different durations, different cultural histories — and they all do the same thing to the brain....
Learn more about psilocybin's impact on the brain and how the trip itself could be just as important as its other therapeutic benefits.
Neuropathic pain is, in a sense, a glitch that refuses to self-correct. The original injury heals, or heals as much as it ever will, but the nervous system keeps insisting otherwis...
Amid a renaissance in the science of psychedelics, public interest in psilocybin — or magic mushrooms, as they’ve long been known — is surging. One study found that rates of psiloc...
Inside a brain on psilocybin, something unusual happens to the signal. The neurons keep firing, more or less as before, but the statistical pattern of that firing changes in a way...
A single dose of psilocybin provides up to a month of nerve pain relief and fundamentally supercharges the efficacy of traditional painkillers.
A massive international study identifies a universal pattern of brain activity across psilocybin, LSD, DMT, and more. Researchers found that all major psychedelics dissolve brain n...
The results of a study carried out in human volunteers given a single dose of psilocybin link changes in brain entropy to insight and suggest that the psychedelic trip itself is im...
A new paper in Nature Communications, covered by Ian Sample at the Guardian, claims a single 25mg dose may leave behind anatomical changes in the wiring itself, still visible 30...
An analysis of hundreds of images from several studies shows how hallucinogenic drugs drive activity in various regions of the brain.
Scientists gave people a “heroic” dose of psilocybin and then looked at their brain. Here’s what happened
In an exciting leap forward for natural product chemistry and plant pathology, researchers have uncovered a novel antibacterial agent from the bitter and hallucinogenic mushroom Gy...
It could lift well-being for up to a month.ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.
(Editor’s Note: President Trump has signed an executive order directing his administration to speed up the review of psychedelic drugs. Although the order focuses on treating menta...
Analysis of more than 500 brain scans finds LSD, psilocybin and other psychedelics increase cross-talk between brain systemsScientists have identified a hallmark signature produced...
Can a single dose of psilocybin replace daily antidepressants? A new randomized clinical trial shows that a 25 mg dose of the psychedelic compound delivers rapid, clinically meanin...
The U.S. Food and Drug Administration is seeking to accelerate the review process for three companies that are studying psilocybin and an MDMA-like drug as treatments for depressio...
Participants who got single dose of psilocybin were more likely to abstain from cocaine than those who got placeboResults from a new clinical trial show that a single dose of psilo...
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