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A groundbreaking study by researchers at the University of California, San Francisco (UCSF), in collaboration with Imperial College London, has unveiled compelling evidence that a...
Low doses of psilocybin made aggressive fish calmer without stopping social interaction, revealing a selective effect on escalated conflict behaviors. More than 200 mushroom specie...
FRIDAY, April 24, 2026 — Psilocybin, the active ingredient in magic mushrooms, is moving into the mainstream. As states move toward decriminalization and the public grows more curi...
Researchers discovered that psilocybin temporarily increases brain complexity and may reshape neural connections for weeks. Researchers at UC San Francisco and Imperial College Lon...
Amid a renaissance in the science of psychedelics, public interest in psilocybin – or magic mushrooms, as they’ve long been known – is surging.
Learn more about psilocybin's impact on the brain and how the trip itself could be just as important as its other therapeutic benefits.
MONDAY, May 18, 2026 — Just a single dose of psilocybin can provide rapid relief from depression, a new small-scale clinical trial has shown. Within a week, people treated with one...
Neuropathic pain is, in a sense, a glitch that refuses to self-correct. The original injury heals, or heals as much as it ever will, but the nervous system keeps insisting otherwis...
Inside a brain on psilocybin, something unusual happens to the signal. The neurons keep firing, more or less as before, but the statistical pattern of that firing changes in a way...
Amid a renaissance in the science of psychedelics, public interest in psilocybin — or magic mushrooms, as they’ve long been known — is surging. One study found that rates of psiloc...
Psilocybin, LSD, mescaline, DMT, and ayahuasca have different chemical structures, different durations, different cultural histories — and they all do the same thing to the brain....
A single dose of psilocybin provides up to a month of nerve pain relief and fundamentally supercharges the efficacy of traditional painkillers.
The results of a study carried out in human volunteers given a single dose of psilocybin link changes in brain entropy to insight and suggest that the psychedelic trip itself is im...
It could lift well-being for up to a month.ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.
Can a single dose of psilocybin replace daily antidepressants? A new randomized clinical trial shows that a 25 mg dose of the psychedelic compound delivers rapid, clinically meanin...
A new paper in Nature Communications, covered by Ian Sample at the Guardian, claims a single 25mg dose may leave behind anatomical changes in the wiring itself, still visible 30...
A massive international study identifies a universal pattern of brain activity across psilocybin, LSD, DMT, and more. Researchers found that all major psychedelics dissolve brain n...
An analysis of hundreds of images from several studies shows how hallucinogenic drugs drive activity in various regions of the brain.
Less is known about psilocybin mushrooms than you might think even as their popularity and potency of products like edibles rises.
(Editor’s Note: President Trump has signed an executive order directing his administration to speed up the review of psychedelic drugs. Although the order focuses on treating menta...
Scientists gave people a “heroic” dose of psilocybin and then looked at their brain. Here’s what happened
Fast-acting and long-lasting.ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.
There are apparently a great many people who at least intermittently use psilocybin. Interestingly, regular dosing with psilocybin has been shown to modestly extend life in mice, b...
Analysis of more than 500 brain scans finds LSD, psilocybin and other psychedelics increase cross-talk between brain systemsScientists have identified a hallmark signature produced...
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