GPR3 Identified as “Signal Amplifier” in Early Neuron Development
G Protein-Coupled Receptor 3 (GPR3) acts as a unique immediate-early molecule that helps trigger the differentiation of stem cells into neurons.
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G Protein-Coupled Receptor 3 (GPR3) acts as a unique immediate-early molecule that helps trigger the differentiation of stem cells into neurons.
Is adult neuroplasticity merely brain development in disguise? A new study reveals that mature neurons do not invent new mechanisms to learn and remember; instead, they re-engage a...
Cortical variations are dictated by the distinct "aging rates" of neural progenitor cells controlled by Wnt signaling pathways.
Scientists discovered that building a healthy brain involves an unexpected step: young neurons routinely break and rapidly repair their own DNA. As the brain develops, newly formed...
Emerging insights into autism spectrum disorder (ASD) have been propelled forward by an innovative study examining cortical development dynamics using multiple mouse models. This w...
Neurogenesis is the process by which new neurons are created in the brain. A common myth is that adults are losing some number of neurons every second and that there is nothing we...
Neonatal brain injury represents a devastating clinical challenge, casting long shadows over developmental trajectories and lifelong neurological function. A groundbreaking study p...
A new study revealed that hundreds of diverse genetic causes of autism converge on shared molecular pathways.
Canadian scientists have demonstrated for the first time that a noninvasive brain-monitoring technique could help medical teams predict the future development of premature babies.
Cellular senescence is required for the proper construction of the brain's protective barrier systems.
Researchers utilized ultra-precise base editing to alter a single nucleotide in human embryos, demonstrating that the NANOG gene is uniquely required to form the body-building epib...
by Sayantanee Biswas, Michelle R. Emond, Grace S. Philip, James D. Jontes Brain dynamics are constrained by the underlying topology of neuronal networks. How genes collaborate to...
A new study demonstrates that axon generation is driven by autonomous internal cellular mechanisms rather than external factors.
Extremely preterm birth (before 28 weeks of gestation) places infants into the world at one of the most extraordinary moments in human development. The brain at this stage is not s...
Difficulty conceiving a pregnancy may be associated with small differences in children's learning and behavior, according to a new study, published in the journal JAMA Network Open...
Researchers demonstrate that the vast cellular complexity of the fruit fly cerebrum can be organized into fewer than 200 foundational "ground plans."
Very preterm infants face up to a 50% higher risk of developmental challenges affecting movement, learning, language and behavior. Today, many of those challenges are not fully rec...
Researchers tracked how direct DNA sequences, indirect "genetic nurture" environments, and parent-of-origin imprinting effects influence a child’s height, BMI, and academic test pe...
A paper published in Molecular Psychiatry, led by researchers from Queen Mary University of London and Royal Holloway, University of London, challenges the way we think about neuro...
Early detection and treatment of congenital cerebral ventriculomegaly (CCV)—when a fetus's fluid-filled brain ventricles swell due to a condition called hydrocephalus—can help clin...
The brain’s language network is still evolving in adolescence. But by age 4, language processing is already handled by the left side of the brain, new research finds.
Participants consistently categorize mental growth into an early-emerging "Perceptual–Experiential" nature dimension and a later-developing "Reflective–Evaluative" nurture dimensio...
Variants in the DHDDS gene cause a severe neurodegenerative condition, characterized by tremors, seizures, coordination and learning difficulties, usually manifesting in early chil...
by Paul Knabl, June F. Ordoñez, Juan Daniel Montenegro Cabrera, Daniel Abed-Navandi, Roland Halbauer, Oliver Link, Tim Wollesen, Grigory Genikhovich In Bilateria with centralized...
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