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A new study provides a cellular-resolution map of Down syndrome brain development, identifying a depletion of progenitor cells as the cause of smaller brain size.
In an era where pediatric healthcare is rapidly evolving, the intricate challenge of managing neurodevelopmental outcomes in children with congenital heart disease (CHD) has garner...
A new study reveals that human peripheral nerve cells commit to their roles much earlier than previously thought, overturning decades of biological assumptions about embryonic deve...
Is adult neuroplasticity merely brain development in disguise? A new study reveals that mature neurons do not invent new mechanisms to learn and remember; instead, they re-engage a...
Differences in brain connectivity are linked to several neurodevelopmental disorders, yet scientists still struggle to determine what changes are shared or unique to each condition...
How does the brain time its own development? A new study explores histone bivalency—an epigenetic "red and green light" system that prevents premature neuron maturation and helps a...
In an unprecedented leap forward in pediatric neurodevelopmental care, a team of researchers has unveiled compelling evidence from a randomized controlled trial illustrating the pr...
Cortical variations are dictated by the distinct "aging rates" of neural progenitor cells controlled by Wnt signaling pathways.
A common recessive NDD caused by RNU2-2 mutations disrupts brain development and opens paths for diagnosis and therapy. Scientists at the Icahn School of Medicine at Mount Sinai in...
The primary cilium is more than an evolutionary leftover; it is a specialized protein factory. Researchers have discovered that these microscopic "antennas" contain localized machi...
In an illuminating new study published in Pediatric Research, researchers have uncovered compelling correlations between neonatal blood glucose measurements and neurodevelopmental...
In recent years, the impact of environmental factors on neurodevelopment has become a critical area of scientific inquiry. Among these factors, high altitude living presents unique...
In a groundbreaking study published in Nature Communications in 2026, researchers Gao, Gu, Ding, and colleagues have unveiled novel insights into the intricate relationship between...
A cellular-resolution map of prenatal brain development in Down syndrome has been developed, revealing disrupted neuron production timing, altered cell types, and shared mechanisms...
In an unprecedented breakthrough that could revolutionize neonatal care, researchers have unveiled compelling evidence that brain complexity in premature newborns, when stimulated...
Neuroscience reveals the brain is shaped through relationships—not in isolation—challenging individualistic psychiatry and psychology and the mental health narrative.
Researchers discovered that a signaling pathway used in brain development is repurposed in adulthood to balance behavioral persistence and flexibility.
Triplet pregnancies carry high risks of prematurity and subsequent neurodevelopmental disorders. Fetal reduction from triplets to twins improves short-term obstetric outcomes, but...
A conceptual split between neurodevelopmental and mental health conditions is helpful, but a clear-cut separation when it comes to service provision and funding support is not.
Researchers discovered RPN1-CDG, a new rare genetic disease. The condition is caused by an RPN1 gene mutation that disrupts how cells attach sugar molecules to proteins.
A longitudinal study of over 6,000 children has found that those with high genetic risk for schizophrenia experience a decrease in frontal brain surface area during early adolescen...
Researchers identified a "purse-string" mechanism powered by actin and molecular motors that physically pulls the neural tube closed during early development.
by Phillip Wulfridge, Nathaniel Rell, John Doherty, Kuo-Chen Fang, Michelle Lee Lynskey, Kavitha Sarma Transition from a pluripotent to a differentiated cell state is accompanied...
A new study uncovers how hyperactive and dysregulated synaptic circuits emerge in the brain tissue of children impacted by Sanfilippo syndrome, a rare genetic condition that causes...
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