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Fresh curated links around neurodegenerative diseases are collected here so marketers can spot useful updates and turn timely ideas into posts faster.
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The major neurodegenerative conditions are characterized by pathology deriving from a small number of misfolded or otherwise altered proteins. Amyloid-β misfolding and aggregation...
by Shiying Liu, Shi-Yan Ng Neuroinflammation and vascular dysfunction are hallmarks of most neurodegenerative diseases. For organoids intended to model neurodegeneration, immune,...
A sweeping review of human neuropathological evidence shows that misfolded SOD1, long tied to familial ALS, coexists with TDP-43, tau, alpha-synuclein, and amyloid-beta across mult...
by Dong Won Kim Neurodegenerative diseases often damage some neuronal populations while sparing closely related neighbors. But instead of asking why some neurons die, should we be...
Alzheimer's disease is a degenerative disease of the nerve cells in the brain that causes impairment of memory and other brain functions -- such as language or perception of realit...
by Shuji Wakatsuki, Toshiyuki Araki Neurodegeneration is frequently associated with oxidative stress, yet the mechanisms that convert reactive oxygen species (ROS) into irreversib...
A spatial multi-omics study in Nature Communications identifies disease-associated oligodendrocytes whose interleukin 33–ST2 signaling influences alpha-synuclein burden and motor s...
The human brain is an extraordinarily expensive organ to run. Although it accounts for only about two percent of body mass, it devours roughly twenty percent of the body’s oxygen s...
Biomarkers that reflect the brain’s workings have been difficult to pin down in neurology studies, but the field has come a long way. The post Changing with the times: what is the...
New research shows that the age-related decline of the mitochondrial protein CHCHD2 disrupts the mitochondria-lysosome axis and drives proteostatic collapse in Lewy body disorders,...
Parkinson's disease and Lewy body dementia are synucleinopathies, characterized by the spread of misfolded α-synuclein through the central nervous system. The presence of misfolded...
Oligodendrocytes resident in the brain are responsible for maintaining the insulating myelin sheaths around axons that are required for the effective transmission of electrical imp...
Nerve damage is a consequence of poorly controlled MS and in one place it is easy to monitor nerve damage and this is in the eye. The eye is connected to your brain and nerve damag...
Every tissue in the body exchanges signals with every other tissue. Every tissue is dependent on specialized functions that are conducted elsewhere in the body. Thus in the matter...
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