Alida Biosciences launches EpiPlex® Tri-Mod™ service for simultaneous profiling of three key mRNA modifications
RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...
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RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...
RNA sequencing with nanopore technology improves m6A modification mapping when paired with calibrated workflows, helping reveal cell-specific RNA regulation in fibroblasts and neur...
RNA sequencing with nanopore technology reveals how diverse therapeutic RNA modifications affect signal detection, helping define current capabilities and limitations for modificat...
RNA sequencing using nanopore technology enables detection of RNA modifications and structure at single-nucleotide resolution through reverse transcription error signatures...
RNA sequencing and protein interaction analyses reveal how a single nucleotide at the start of RNA can alter antiviral immune signaling and influence therapeutic RNA design...
The platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold. In human cell lines, ΨDNA achieved 70–95% knockdown of endogenou...
Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps...
RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...
by Isabel Sola, Sonia Zuñiga Non-spike changes driving SARS-CoV-2 fitness remain undercharacterized. Two PLOS Biology papers show that evolutionary N gene changes create a transcr...
In the intricate landscape of genetic regulation, the study of RNA-binding proteins is unraveling new dimensions of molecular control mechanisms pivotal for development and disease...
RNA sequencing with NTVE enables repeated monitoring of gene expression in living cells, supporting time-course analysis of differentiation, perturbation responses, and cellular dy...
RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...
In a groundbreaking advancement in the field of environmental health science, researchers at the University of Chicago have unveiled a highly sensitive epigenetic biomarker capable...
RNA sequencing reveals how transposable elements drive alternative splicing and alter translation in glioblastoma, generating diverse RNA isoforms linked to cancer progression...
RNA sequencing with the new sm-PORE-cupine method reveals how individual RNA molecules fold and behave, offering insights into gene regulation, viral biology, and therapeutic disco...
by Maik Mendler, Kristin Krause, Simone Zündorf, Prathamesh Sannak, Petra Tänzler, Sara Stolze, Hirofumi Nakagami, Franziska Turck Epigenetic regulators shape chromatin landscapes...
In a groundbreaking study published in Cell Research, researchers have leveraged population-scale multi-omics approaches to uncover the extensive and nuanced roles of long non-codi...
This week we dive into the Beyond Biotech archive to bring you a discussion with Dr Stanley Qi, the founder of Epicrispr. The post How Epicrispr is leveraging CRISPR without cutti...
In a remarkable breakthrough poised to deepen our understanding of epigenetic regulation, researchers have unveiled new insights into the molecular mechanisms by which MeCP2, a cri...
A 2026 paper reports on an AI trained on genomic data, including data from a 2024 paper, enabling it to predict when transcription would be initiated. Source
DARPA is looking to write and erase epigenetic base modifications in DNA that could be used for cognitive enhancement, biological threats protection, and regenerative medicine. The...
The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the emphasis has been on its underlying mechanisms and nuclea...
RNA sequencing using reference-free analysis uncovers novel transcripts and hidden gene features, expanding discovery beyond traditional genome-based approaches...
RNA sequencing and new computational tools enabled construction of a large RNA interactome atlas linking RNA-binding proteins, RNA interactions, and gene regulation...
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