Social Media Ideas for Epitranscriptomics

Latest updates for Epitranscriptomics

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rna-seqblog.com /2 weeks ago

Nanopore direct RNA sequencing expands the view of the transcriptome

RNA sequencing using nanopore direct RNA sequencing enables simultaneous analysis of native RNA molecules, transcript isoforms, RNA modifications, and poly(A) tails for comprehensi...

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rna-seqblog.com /1 month ago

Nanopore sequencing advances pseudouridine detection in ribosomal RNA

Nanopore direct RNA sequencing enables accurate, site-specific quantification of pseudouridine modifications in human ribosomal RNA, expanding opportunities for large-scale epitran...

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phys.org /1 month ago

Epigenetic changes can be inherited without changing DNA in animals

Typically, the information encoded in DNA allows organisms to develop, function, and pass traits across generations. Yet DNA alone does not explain how genes are switched on and of...

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rna-seqblog.com /3 weeks ago

Systematic benchmarking of dorado basecalling models for RNA modification detection

..Nanopore RNA sequencing models can detect RNA modifications, but benchmark results reveal significant false positives and highlight the importance of controls for accurate epitra...

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rna-seqblog.com /1 month ago

m6A-ARTR-DBiT – mapping RNA modifications across tissues with spatial m6A profiling

Spatial RNA sequencing and m6A profiling reveal how RNA modifications vary across tissues, uncovering region-specific patterns of gene regulation in developing and adult... The pos...

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bioengineer.org /2 weeks ago

N4-Acetylcytidine Boosts Synthetic mRNA Translation

In a groundbreaking advancement for synthetic mRNA therapeutics, recent research unveils how the chemical nature of nucleotide modifications profoundly influences ribosome behavior...

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rna-seqblog.com /1 month ago

CAMP4 Therapeutics preprints pioneering study on regulatory RNA profiling and gene upregulation

RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...

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scienceandculture.com /2 weeks ago

Epigenome Is Biology’s Second Revolution

Thomas Woodward compares the epigenetic system to a supercomputer where information is written everywhere — on the hardware, the screen, and even the keys. Source

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bioengineer.org /1 week ago

Lysine Pyruvylation Links Glycolysis to Epigenetics

In a groundbreaking advancement that reshapes our understanding of cellular metabolism and epigenetic regulation, researchers have unveiled a novel post-translational modification...

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rna-seqblog.com /1 month ago

MSK scientists uncover RNA’s hidden role as protein chaperone

RNA sequencing continues to reveal unexpected RNA functions, including how mRNA 3′UTRs help regulatory proteins fold correctly and maintain proper cellular activity... The post MSK...

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scitechdaily.com /3 weeks ago

A Surprising Discovery Challenges What Scientists Thought DNA Methylation Was For

DNA carries the instructions for life, but additional molecular systems help determine how those instructions are used. New research in a sea anemone reveals an unexpected role for...

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bioengineer.org /1 month ago

RBM20 Isoform Control Shapes Splicing in Health

In the intricate landscape of genetic regulation, the study of RNA-binding proteins is unraveling new dimensions of molecular control mechanisms pivotal for development and disease...

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rna-seqblog.com /3 weeks ago

New approach reveals how complete riboswitches control gene expression

RNA sequencing combined with high-throughput functional profiling enabled researchers to build complete riboswitch models and uncover coordinated structural changes involved in gen...

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journals.plos.org /3 weeks ago

Beyond the canonical: The role of post-transcriptional regulation in drug-target interaction prediction

by Md Istiaq Ansari, Khandakar Tanvir Ahmed, Debby D. Wang, Kirill Medvedev, Wei Zhang Protein isoforms produced from the same gene through post-transcriptional regulatory mechani...

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rna-seqblog.com /1 month ago

New eBook | RNA-seq: A peek inside the transcriptome

This collection highlights how RNA sequencing is advancing transcriptomics research, from single-cell analysis and disease mechanisms to nanopore sequencing and AI-driven data inte...

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bioengineer.org /1 month ago

Precise Gene Control Using FDA-Approved RNA Splicing Drug

In a groundbreaking advance poised to reshape gene therapy and molecular medicine, researchers have unveiled a novel strategy for precise gene regulation via RNA splicing modulatio...

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genengnews.com /1 month ago

mRNA Tails Play Key Role in Folding Regulatory Proteins

While 3' UTRs have traditionally been dismissed as key regulators, a new study shows that these highly conserved mRNA tails facilitate the folding of intrinsically disordered prote...

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rna-seqblog.com /1 month ago

A hidden switch fine-tunes the heart’s elasticity

RNA sequencing reveals that RBM20 uses multiple transcription start sites, producing distinct protein isoforms that influence heart development, cardiomyopathy, and heart muscle fu...

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scienceandculture.com /1 month ago

Garbage Goodbye: In Blow to Junk RNA, “Majority” of Transcription Not “Background Noise”

A 2026 paper reports on an AI trained on genomic data, including data from a 2024 paper, enabling it to predict when transcription would be initiated. Source

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rna-seqblog.com /1 month ago

Study is first demonstration of gene transcription measurement in the living brain

A new blood-test platform enables noninvasive monitoring of gene expression in living tissues over time, complementing RNA sequencing approaches for studying disease progression......

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bioengineer.org /3 weeks ago

Engineering Drug-Responsive RNA for Precise Control

In a groundbreaking advance poised to reshape the landscape of RNA therapeutics, researchers have engineered a novel drug-responsive replication machinery capable of exerting exqui...

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activistpost.com /1 month ago

DARPA ‘D-PECHE’ looks to epigenetic modification for human cognitive enhancement, biothreat protection, regenerative med...

DARPA is looking to write and erase epigenetic base modifications in DNA that could be used for cognitive enhancement, biological threats protection, and regenerative medicine. The...

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scientificamerican.com /2 weeks ago

Gene-editing startups are using CRISPR to treat diseases

A handful of start-up firms are testing therapies that target specific epigenetic markers to treat everything from high cholesterol to a rare muscular disorder

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scienceandculture.com /3 weeks ago

Paper in Cell Reports “Paradigm Shift” Against TEs as “Genomic Parasites or Junk DNA”

This language is remarkable coming from a journal often considered the third most important in the world for biology. Source

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