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Alzheimer's disease is a degenerative disease of the nerve cells in the brain that causes impairment of memory and other brain functions -- such as language or perception of realit...
Oligodendrocytes resident in the brain are responsible for maintaining the insulating myelin sheaths around axons that are required for the effective transmission of electrical imp...
Parkinson’s disease research has taken a significant step toward a strategy that attacks one of the disorder’s most persistent biological problems: the accumulation of misfolded al...
Researchers identify link that could aid earlier diagnosis of Progressive Supranuclear Palsy
In this webinar, The post Is Targeted Protein Degradation the “Break” Neurology Needs? appeared first on GEN - Genetic Engineering and Biotechnology News.
The retina is a part of the central nervous system, and as such is subject to a variety of forms of age-related neurodegeneration, culminating in conditions such as macular degener...
study shows NAC antioxidant therapy bypasses 22q11.2 deletion syndrome deficits via alternative gene networks.
Parkinson’s disease and multiple system atrophy can begin with remarkably similar symptoms: slowed movement, stiffness, tremor, balance problems and changes in speech. Yet beneath...
A new study identifies the neural circuit linking memory impairment to apathy in patients with autoimmune limbic encephalitis.
The human brain is an extraordinarily expensive organ to run. Although it accounts for only about two percent of body mass, it devours roughly twenty percent of the body’s oxygen s...
Researchers generated a single-cell atlas of the striatum, identifying 31 neuronal subpopulations and disease-linked vulnerabilities that could inform studies of Huntington’s disea...
by Isabel Hubbard, Josh Dubnau The most common genetic cause of both familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is an expanded G4C2 repeat in t...
Some brains seem to defy Alzheimer's. Even when the disease's telltale plaques and tangles are present, certain individuals remain mentally sharp well into old age. This phenomenon...
Measuring Predictive Age Difference (PAD), the team found that Alzheimer’s disease and mild cognitive impairment showed the highest accelerated brain aging, followed by psychiatric...
Alzheimer’s disease has long been associated with the accumulation of tau, a neuronal protein that normally helps organize and stabilize microtubules inside axons. In the disease,...
A new study shows that 3D genome architecture is altered in prefrontal cortex cells of individuals with Alzheimer's disease.
Age-related oligodendrocyte dysfunction may contribute to cognitive decline by disrupting myelin and large nerve fibers. Myelin is essential for fast communication in the brain, fo...
Huntington’s disease is an inherited condition that gradually robs people of their ability to move, speak and even think clearly—there is no cure
A new study demonstrates that early-onset dementia is associated with severe work productivity losses up to 15 years before a formal diagnosis.
Neurogenesis is the name given to the creation of new neurons in the central nervous system, arising from neural stem cell populations, maturing, and then merging with existing neu...
Nerve damage is a consequence of poorly controlled MS and in one place it is easy to monitor nerve damage and this is in the eye. The eye is connected to your brain and nerve damag...
Senescent cells accumulate with age in tissues throughout the body, disrupting tissue structure and function with inflammatory secretions. The growing burden of senescent cells is...
Parkinson's disease and Lewy body dementia are synucleinopathies, characterized by the spread of misfolded α-synuclein through the central nervous system. The presence of misfolded...
Motor neurone disease - known as MND - affects 5,000 adults in the UK at any one time, with about 1,100 diagnosed each year. The numbers seem to be rising steadily - and, crucially...
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