Fly Genetics Simplifies Mammalian Neurobiology Models
Researchers demonstrate that the vast cellular complexity of the fruit fly cerebrum can be organized into fewer than 200 foundational "ground plans."
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Researchers demonstrate that the vast cellular complexity of the fruit fly cerebrum can be organized into fewer than 200 foundational "ground plans."
Larval zebrafish utilize a preglomerular complex (PG) and pallium hierarchy to sort and merge sensory streams, replicating the exact computational logic of the mammalian thalamocor...
A new study demonstrates that individual human cortical neurons possess the computational complexity of an entire deep artificial neural network.
Is adult neuroplasticity merely brain development in disguise? A new study reveals that mature neurons do not invent new mechanisms to learn and remember; instead, they re-engage a...
Who is responsible for negative behavior, such as sexual compulsions, that is driven by biological changes in the brain? Here, a neurologist reflects on the difficult question of f...
A spatial single-cell brain atlas of the jawless lamprey reveals that the common ancestor of all vertebrates possessed a highly complex molecular brain architecture 450 million yea...
by Paul Knabl, June F. Ordoñez, Juan Daniel Montenegro Cabrera, Daniel Abed-Navandi, Roland Halbauer, Oliver Link, Tim Wollesen, Grigory Genikhovich In Bilateria with centralized...
Neurogenesis is the process by which new neurons are created in the brain. A common myth is that adults are losing some number of neurons every second and that there is nothing we...
How does the brain coordinate complex behaviors across multiple overlapping circuits simultaneously? A breakthrough imaging pipeline introduces Neuroplex, a method that tracks up t...
G Protein-Coupled Receptor 3 (GPR3) acts as a unique immediate-early molecule that helps trigger the differentiation of stem cells into neurons.
By capturing these pristine intracranial signals, the study introduces an objective, measurable biomarker to optimize deep-brain therapies and revolutionize our clinical understand...
A functional whole-brain imaging study reveals that blind Mexican cavefish evolved an inverted behavioral response to light by repurposing existing neurons in the posterior tubercu...
Brain cells take in many signals through thousands of circuit connections. A new study discerns the rules that turn inputs into a functional arrangement for neurons that process vi...
By explicitly linking reinforcement-driven human neuroplasticity with gradient-based decoder optimization, the framework unifies biological trial-and-error learning with mathematic...
by Guillermina Griffa, Marco Palombo, Abraham Yeffal, Hong-Hsi Lee, Agustin Solano, Susie Y. Huang, Valeria Della-Maggiore Structural neuroplasticity supports learning, developmen...
New division centralizes years of internal research into Human Context Intelligence, creating a dedicated platform for scientific development, benchmarks, datasets, and external pa...
by Sayantanee Biswas, Michelle R. Emond, Grace S. Philip, James D. Jontes Brain dynamics are constrained by the underlying topology of neuronal networks. How genes collaborate to...
Behavioral economics needs biology. How lived experience, emotion, and development shape the choices people make.
Bilingual brains store concepts on a single, shared semantic map inside the hippocampus, using distinct clusters of language-specific neurons to navigate the map from different per...
By leveraging ankyrin-2 (Ank2) to regulate BDNF/TrkB.T1 calcium signaling, astrocytes undergo structural remodeling to physically encapsulate and stabilize memory-storing engram ne...
The global framework validates the "last in, first out" theory of brain aging while revealing that individuals sharing the same clinical diagnosis exhibit completely unique microst...
A new study has unveiled the first complete, synapse-level wiring diagram, or connectome, of an adult fruit fly’s central nervous system.
[lightweight-accordion title="Show answer" title_background="#efefef" bordered=true]Neurology.[/lightweight-accordion]
by Hugues Berry, Lyle J. Graham, Kim T. Blackwell
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