Latest updates for G3: Genes Genomes Genetics

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Recent items include:

  • GPC: An expressive and tractable deep generative model for genetic variation data
  • Pervasive context-dependent effects in the genetic architecture of complex and quantitative traits revealed by a powerfu
  • Development of a low-coverage whole genome sequencing screen for apomixis using a diverse set of <i>Malus</i&gt

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journals.plos.org /2 weeks ago

GPC: An expressive and tractable deep generative model for genetic variation data

by Prateek Anand, Anji Liu, Meihua Dang, Boyang Fu, Xinzhu Wei, Guy Van den Broeck, Sriram Sankararaman Generative models play an important role in population genetics, being used...

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journals.plos.org /1 month ago

Pervasive context-dependent effects in the genetic architecture of complex and quantitative traits revealed by a powerfu...

by Gareth A. Cromie, Russell S. Lo, Lauren Ames, Trey S. Morgan, Katherine Owens, Anne E. Clark, Martin S. Timour, Julee Ashmead, Michelle Tang, J. Nathan Kutz, Joshua M. Akey, Aim...

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journals.plos.org /1 month ago

Development of a low-coverage whole genome sequencing screen for apomixis using a diverse set of &lt;i&gt;Malus&lt;/i&gt...

by Charity Z. Goeckeritz, Václav Polcar, Benjamin Gutierrez, Tomáš Urfus, Alex Harkess In the past decade, plant biologists have made several major discoveries pertaining to the g...

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journals.plos.org /1 month ago

Assessing Hardy-Weinberg equilibrium in T2T-aligned 1000 genomes project

by Elika Garg, Jaffa Romain, Lei Sun, Andrew D. Paterson Quality control of markers in genome-wide association studies often includes testing for Hardy-Weinberg equilibrium (HWE)....

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botany.one /5 days ago

Science Shared: October 17

This week: Genetics dominates the most shared papers of the week

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ipscell.com /4 days ago

Weekly reads: G&amp;D trio, Regenative Labs sues FDA, OCT4 sub, SpudCells, SRSF1 as an anti-aging factor?

Early on in my career as a graduate student in Mark Kamps’ lab, we had some go-to journals like G&amp;D and MCB. Such journals often published papers in our areas of interest on Ho...

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genengnews.com /2 weeks ago

DNA Typewriter, PEtracer Map Mouse Development Through Organogenesis

Two DNA-recording systems traced cellular family trees across mouse embryogenesis, offering new insight into how organs form and when developing cells commit to specific fates. The...

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journals.plos.org /1 week ago

DipSkmer: Reference-free population genomics with diploid genome skims

by Eduardo Charvel, Homère J. Alves Monteiro, Siavash Mirarab, Vineet Bafna Ecologists and conservation biologists rely on genetic diversity as a key essential biodiversity variab...

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journals.plos.org /1 month ago

Direct microhaplotype genotyping for GT-seq (Genotyping-in-Thousands by Sequencing) using a diploid abundance model

by Nathan R. Campbell, Amanda R. Campbell, Shannon K. Blair, Amanda J. Finger GT-seq (Genotyping-in-Thousands by Sequencing) is widely used for high-throughput amplicon genotyping...

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journals.plos.org /1 month ago

Not every gene is special: Modelling scale controls the false discovery rate when analysing high-throughput sequencing d...

by Scott J. Dos Santos, Andreea C. Murariu, Justin D. Silverman, Gregory B. Gloor Differential expression/abundance analyses are commonplace in studies employing high-throughput s...

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genengnews.com /1 month ago

The DNA Balancing Act in Boosting Bacterial Productivity

A new mathematical model tracks how plasmids move through competing E. coli populations, revealing how antibiotics, genetic costs, and plasmid loss could shape biotechnology cultur...

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genengnews.com /2 weeks ago

Biologics Standards for Innovation, Quality and Access

This GEN Spotlight on Biologics Standards for Innovation, Quality and Access brings together experts from across biopharma, standards development, and analytical science to examine...

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genengnews.com /2 weeks ago

A Method for Assessing Lab-Grown Stem Cell-Derived Embryo Models

Researchers developed a method for testing how closely lab-grown blastoid models resemble real human embryos, finding that while some models perform well, none fully captures the c...

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botany.one /1 month ago

The End of Papaya?: What Genomics Teaches Us About Its Survival

A study of papayas in Mexican backyards reveals how hybridisation between wild and cultivated plants can boost genetic diversity while creating new challenges for conservation.

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genengnews.com /6 days ago

ASHG 2026 Awards Honor Achievements in Research, Education, and More

ASHG will honor seven recipients with its 2026 Professional Awards, recognizing outstanding contributions to human genetics and genomics research, education, mentorship, and public...

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genengnews.com /6 days ago

Designing the Ecosystem for CGT Success

This proceedings eBook, developed in partnership with GEN and Cincinnati Children’s Hospital Applied Gene and Cell Therapy Center, captures perspectives and lessons from The Cell S...

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journals.plos.org /1 month ago

Bacterial chromosomal gene positioning is likely shaped by selection on both mean and growth-dependent expression

by Ruiqi Yuan, Jianzhi Zhang In bacteria with circular chromosomes, genes near the replication origin (oriC) are replicated earlier and consequently attain higher copy numbers tha...

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rna-seqblog.com /4 weeks ago

Single-cell TimeLapse-seq reveals MTA is an essential retrotransposon

Very early in development, an embryo must begin using its own genome instead of relying only on RNA and proteins inherited from the egg. This transition is known as zygotic genome...

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labiotech.eu /2 days ago

Great gene editing. Now prove it without overcomplicating the analysis

Gene editing is moving from lab bench to approved therapies. But how should sponsors measure editing efficiency without unnecessary complexity? The post Great gene editing. Now pro...

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genengnews.com /2 weeks ago

Flicking the Switch: Five Scientists Honored at 2026 Warren Alpert Foundation Symposium for Hemoglobinopathy Research

Stuart Orkin, MD, and his former trainees Vijay Sankaran, MD, PhD, and Daniel Bauer, PhD, were joined by Swee-Lay Thein, MD, PhD, and John Tisdale, MD, both at the NIH. Their contr...

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bioengineer.org /1 week ago

Low-Coverage Genome Sequencing Uncovers Hidden Clonal Seed Formation in Apple Relatives

A low-coverage whole-genome sequencing screen of USDA apple germplasm identified 17 previously unknown apomictic genotypes, offering a cheaper, faster method for detecting clonal s...

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bioengineer.org /1 week ago

Where a Gene Sits on the Bacterial Chromosome May Shape Its Expression Through Selection

A new PLOS Genetics study finds that bacterial gene positions along the chromosome show gradients in mean and growth-dependent expression consistent with selection shaped by replic...

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journals.plos.org /1 month ago

Balanced DNA interpolation improves learning of genetic distance-informed embeddings in plants

by Lara M. Kösters, Kevin Karbstein, Ladislav Hodač, Laura Albreht, Elvira Sahuquillo Balbuena, Daniel Botello, Olivier Hardy, Phebian Odufuwa, Eva Pardo Otero, Aireen Phang, Manue...

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genengnews.com /1 week ago

Multiomics in 2026 and Beyond

Multiomics analysis combines data from two or more omics layers—such as genomics, transcriptomics, proteomics, and epigenomics. However, published criticisms of multiomics approach...

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Sources covering G3: Genes Genomes Genetics

bioengineer.org

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feeds.feedburner.com

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ipscell.com

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journals.plos.org

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journals.plos.org

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botany.one

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