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bioengineer.org /1 month ago

Motor Neuron Disease Deaths Rise in the US, but Age-Adjusted Rates Hold Steady

A sweeping new analysis of more than a quarter century of American death records has found that while the absolute number of people dying from motor neuron disease in the United St...

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goodmenproject.com /1 month ago

5 Things to Know About ALS

An expert answers questions about the degenerative neurological disease — and works to defeat it The post 5 Things to Know About ALS appeared first on The Good Men Project.

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bioengineer.org /3 weeks ago

Approved Metabolism Drugs Rescue Disease Signs in SMA Mice

Spinal muscular atrophy has long been understood as a disease of motor neurons, a genetic condition in which the progressive loss of nerve cells that control skeletal muscles leave...

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fightaging.org /1 month ago

MERKT is Involved in Enabling Microglia to Kill Motor Neurons in ALS

Amyotrophic lateral sclerosis (ALS) is characterized by the loss of motor neurons. Aggregation of TDP-43 is thought to be involved in producing cell death in the brain. Here resear...

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scitechdaily.com /1 month ago

Scientists Discover Immune Cells Are Eating Living Neurons in ALS

Salk Institute scientists found that immune cells in the central nervous system identify and kill specific nerve cells in the spinal cords of mice with late-stage ALS, worsening th...

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bioengineer.org /1 week ago

Silencing SLITRK2 Rescues Damaged Nerve-Muscle Connections in FUS-ALS Motor Neurons

Researchers found that reducing SLITRK2 levels in human stem cell-derived FUS-ALS motor neurons restores axonal health and neuromuscular junction signaling, offering a new molecula...

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rna-seqblog.com /3 days ago

Transcripta Bio Announces Research Collaboration to Advance Discovery of New ALS Treatments

Transcripta Bio and Mayo Clinic will combine single-cell RNA sequencing with AI-driven analysis of patient-derived ALS tissue to identify disease signatures and potential therapeut...

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bioengineer.org /2 weeks ago

Beyond ALS: Misfolded SOD1 Emerges as a Shared Player in Brain Disease

A sweeping review of human neuropathological evidence shows that misfolded SOD1, long tied to familial ALS, coexists with TDP-43, tau, alpha-synuclein, and amyloid-beta across mult...

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neurology.ufl.edu /1 week ago

Exciting News for the Neuromuscular Community!

We are thrilled to share that Dr. Sub Subramony, MD, Professor of Neurology at the University of Florida, has been selected by the Muscular Dystrophy Association (MDA) and TREAT-NM...

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medicalxpress.com /1 week ago

Asthma drug improves motor function and strength in children with rare muscle diseases in small trial

Congenital myopathies are a group of rare, inherited muscle diseases that often cause muscle weakness in childhood. This weakness can affect, among other things, the ability to wal...

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bioengineer.org /2 weeks ago

Early Weight Loss in ALS Signals Faster Decline, but Standard Energy Formulas Fall Short

A prospective Australian study shows that early weight loss in amyotrophic lateral sclerosis marks a subgroup with faster decline and roughly five-fold higher mortality, while exis...

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