Latest updates for Transcriptomics

Fresh curated links around transcriptomics are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • New method allows scientists to follow gene activity over time in the same cells
  • New method allows scientists to follow gene activity over time in the same cells
  • Transcriptomic Approaches to Guiding the Discovery of Geroprotective Compounds

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webwire.com /1 month ago

New method allows scientists to follow gene activity over time in the same cells

The following press release was issued by the Broad Institute of MIT and Harvard. - - In recent years, scientists have built methods to measure a cell's transcriptome, or all t...

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rna-seqblog.com /1 month ago

New method allows scientists to follow gene activity over time in the same cells

Live-cell RNA sequencing uses engineered virus-like particles to repeatedly sample transcriptomes without destroying cells, enabling researchers to track gene expression changes ov...

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fightaging.org /1 week ago

Transcriptomic Approaches to Guiding the Discovery of Geroprotective Compounds

A great deal of drug discovery starts by screening compounds from the vast libraries of molecules that exist. The libraries are too large to screen everything (and even then the sc...

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rna-seqblog.com /1 month ago

A real-data approach to evaluating RNA transcript analysis methods

RNA sequencing data provide a real-world framework for comparing differential transcript usage methods across bulk, single-cell, spatial, long-read, and short-read transcriptomics....

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genengnews.com /2 weeks ago

The Epitranscriptome Heads Toward Clinical Necessity

Short-read RNA sequencing reporting the modifications that alter protein output is starting to make epitranscriptomics indispensable for patient selection in precision medicines. T...

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rna-seqblog.com /3 weeks ago

The Human RNome Project Consortium seeks to publish first-ever complete sequence of the body’s RNA

RNA sequencing efforts from the Human RNome Project aim to build a comprehensive reference of human RNA sequences, isoforms, processing states and chemical modifications...

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rna-seqblog.com /1 month ago

POND-seq enables non-destructive RNA sequencing in living cells

POND-seq enables non-destructive RNA sequencing of living cells, allowing repeated measurement of transcriptomes and RNA-binding protein interactions as cells respond to changing c...

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rna-seqblog.com /1 month ago

Spatial mapping of RNA turnover kinetics in the mouse brain

Spatial RNA sequencing maps RNA synthesis and degradation across the mouse brain, revealing how different regions rapidly adjust gene expression in response to stimulation...

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bioengineer.org /2 weeks ago

Rumen Fluke Parasite Reveals Its Molecular Playbook Across Life Stages

A new transcriptomic study of the rumen fluke Calicophoron daubneyi reveals that its eggs, rediae and cercariae each deploy distinct gene programs tuned to survival, proliferation...

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rna-seqblog.com /1 day ago

Recordanelles enable RNA sequencing to capture a history of gene activity in living cells

Researchers developed recordanelles that preserve gene expression histories for days, allowing single-cell RNA sequencing to detect transient cellular responses that conventional m...

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journals.plos.org /4 weeks ago

Integrating zero-inflation correction and transcriptional kinetics for single-cell transcriptomic analysis

by Chengkai Yang, Yu Liao, Ying Sheng, Feng Jiao Single-cell transcriptomic data exhibit pervasive zero inflation, while traditional models either neglect this issue or fail to ca...

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genengnews.com /1 month ago

Spatial Transcriptomics Tools May Link Tumor Organization to Treatment Response

A new spatial transcriptomics framework compares tumor “floor plans." In a study of 262 solid tumors, the team identified recurring spatial groups that may connect spatial structur...

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rna-seqblog.com /2 days ago

RNA sequencing reveals how genes combine to regulate inflammation and immune responses

Long-read RNA sequencing reveals functional chimeric mRNAs formed from distant genes, identifying a previously unknown protein that regulates inflammation, antibacterial immunity a...

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rna-seqblog.com /1 month ago

An end-to-end computational framework for “Record-seq” transcriptional recording data

A new framework adapts RNA sequencing analysis for Record-seq, improving spacer extraction, transcription-unit quantification, normalization, differential expression, and modeling...

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rna-seqblog.com /3 weeks ago

Therna Biosciences Releases Chronos, the Data Engine Behind its AI RNA Biologist

RNA sequencing with Therna’s Chronos platform measures millions of RNA behaviors across diverse human cell types, creating large datasets for modeling expression, stability a...

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journals.plos.org /1 month ago

Characterization of METTL3/14-mediated m<sup>6</sup>A modification in human transcriptome using Nanopore dir...

by Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism....

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rna-seqblog.com /1 month ago

Single-cell TimeLapse-seq reveals MTA is an essential retrotransposon

Very early in development, an embryo must begin using its own genome instead of relying only on RNA and proteins inherited from the egg. This transition is known as zygotic genome...

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journals.plos.org /2 weeks ago

Spatial Transcriptomics As Rasterized Image Tensors (STARIT) characterizes cell states with subcellular molecular hetero...

by Dee Velazquez, Caleb Hallinan, Roujin An, Kalen Clifton, Jean Fan Imaging-based spatially resolved transcriptomics (imSRT) technologies provide high-throughput molecular-resolu...

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rna-seqblog.com /2 weeks ago

Novel biosensor uses DNA ‘barcodes’ to uncover disease signals in cells

RNA sequencing can read Detectron-generated DNA barcodes, enabling scalable detection of specific RNA signals associated with infection, gene activity and other cellular processes....

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genengnews.com /2 weeks ago

DNA Typewriter, PEtracer Map Mouse Development Through Organogenesis

Two DNA-recording systems traced cellular family trees across mouse embryogenesis, offering new insight into how organs form and when developing cells commit to specific fates. The...

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bioengineer.org /1 month ago

Multi-omics reveals metabolic regulation of petal color in Phalaenopsis

In a finding that is already rippling through the world of ornamental plant science, researchers in China have pieced together, gene by gene and pigment by pigment, the molecular m...

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nanowerk.com /1 month ago

A Google-like search engine for single-cell RNA

Scientists have built a search engine that can scan data from millions of single cells from thousands of experiments worldwide in seconds. The tool makes it possible to answer prev...

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rna-seqblog.com /1 month ago

RNA sequencing reveals functional chimeric mRNAs in mammalian immunity

Direct RNA sequencing revealed thousands of chimeric mRNAs in mammalian cells, uncovering previously unknown proteins with roles in immunity, inflammation, and potential drug disco...

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rna-seqblog.com /1 month ago

RNA variant imaging for cancer diagnosis

RNA Variant Imaging is attracting attention because it addresses a persistent blind spot in cancer diagnostics: many clinically relevant RNA isoforms, splice events, and fusion tra...

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Sources covering Transcriptomics

rssfeeds.webwire.com

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bioengineer.org

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feeds.feedburner.com

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journals.plos.org

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journals.plos.org

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fightaging.org

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