Search results for Targeted Therapy

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medicalxpress.com /1 month ago

New targeted therapy shows promise against aggressive childhood and adult cancers

Researchers at the University of British Columbia Faculty of Medicine have developed a new targeted cancer therapy that can precisely seek out and destroy tumor cells—showing stron...

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genengnews.com /1 month ago

Targeted Precision, Complex Promise

Antibody-drug conjugates (ADCs) have evolved from an elegant scientific concept into one of oncology’s most dynamic therapeutic classes. By fusing the targeting specificity of mono...

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bioengineer.org /1 week ago

Targeted Therapy Advances in H3K27-Altered Glioma

In an era where cancer research continually pushes the boundaries of personalized medicine, a groundbreaking study has emerged, promising newfound hope for patients suffering from...

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bioengineer.org /1 month ago

Targeting Master Regulators: A Unified Cancer Therapy

In a transformative leap forward for cancer therapy, a groundbreaking study published in Cell Death Discovery unveils a unified therapeutic theory that holds the potential to revol...

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rna-seqblog.com /1 month ago

Bostongene RNA transcriptome profiling reveals new ADC targets in advanced solid tumor

RNA sequencing combined with multiomic analysis uncovers new therapeutic targets in advanced cancers, enabling identification of antibody drug conjugate options when DNA testing al...

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healio.com /1 month ago

Agent extends survival in metastatic pancreatic cancer

An investigational targeted therapy doubled survival compared with standard chemotherapy for pretreated individuals with metastatic pancreatic cancer, according to topline data rel...

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bioengineer.org /1 month ago

26 Years of Advancing EGFR-TKIs in Non-Small Cell Lung Cancer: Breakthroughs in Clinical Use and Resistance Mechanisms

Over the past three decades, the landscape of non-small cell lung cancer (NSCLC) treatment has been profoundly transformed by the advent and continued evolution of epidermal growth...

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bioengineer.org /2 weeks ago

New Targeted Radiopharmaceutical Therapy Achieves Remission in Pancreatic Cancer Model

A groundbreaking advancement in the field of targeted radiopharmaceutical therapy heralds a new era for treating pancreatic ductal adenocarcinoma (PDAC), a notoriously aggressive a...

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bioengineer.org /17 hours ago

Peptide-Directed, Hypoxia-Sensitive AAV System Enables Tumor-Specific Delivery of Chemokines and PNAi in Non-Small Cell...

In a bold leap toward precision oncology, researchers have proposed an innovative adeno-associated virus (AAV) vector system engineered to selectively target non-small cell lung ca...

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nanowerk.com /1 month ago

CRISPR variant selectively targets tumor DNA

New gene-editing techniques exploit unique chemical fingerprints in cancer DNA to selectively destroy tumor cells, paving the way for precision therapy.

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genengnews.com /1 month ago

Prostate Cancer Therapy Targets Disordered Region of Androgen Receptor

A new study designs drugs that bind to intrinsically disordered proteins, which play a central role in cancer, neurodegenerative disorders, heart disease, and autoimmune conditions...

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news-medical.net /1 week ago

Study reveals cellular mechanisms driving resistance to targeted cancer therapies

Despite impressive innovations in medicine, most advanced-stage cancers still carry a grim prognosis. Developing more effective treatments requires a deeper understanding of the ce...

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bioengineer.org /1 week ago

Targeted Radiotherapy Extends Control of Early-Stage Breast Cancer Spread

In a groundbreaking development presented at the European Society for Radiotherapy and Oncology (ESTRO) Congress 2026, researchers have illuminated promising advances in the treatm...

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genengnews.com /1 month ago

High-Throughput Platform for Fast-Acting Covalent Protein Therapies

Using this new platform, researchers developed a covalent antagonist targeting PD-L1, termed IB101, which was found to form a defined binding pocket that precisely positions the ac...

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bioengineer.org /1 month ago

New [225Ac]-Pertuzumab Drug Shows Potent HER2 Fight

In the relentless battle against HER2-positive breast cancer, a groundbreaking breakthrough is emerging from the cutting-edge intersection of radiopharmaceuticals and targeted ther...

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fiercebiotech.com /1 month ago

Drug combo treats multiple cancers with ‘paradox’ mutation in mice

A detailed look at a mysterious mutation present in many different cancer types has revealed new drug targets that, when hit with a combo of well-known compounds, led to tumor cell...

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bioengineer.org /1 month ago

Molecular Profiles Guide Targeted and Immunotherapy in SCLC

Small cell lung cancer (SCLC) remains one of the most formidable challenges within oncology, not just due to its aggressive clinical course but also as a consequence of its complex...

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news-medical.net /1 week ago

Targeted radiotherapy may delay progression in metastatic breast cancer patients

Treating breast cancer that has begun to spread around the body with targeted radiotherapy could help patients to live longer without their cancer getting worse, according to the r...

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bioengineer.org /1 week ago

Harrington Discovery Institute Uncovers Novel Drug Targets for Challenging Cancer Types

Despite remarkable progress in medical science, the prognosis for most patients diagnosed with advanced-stage cancers remains bleak. The challenge lies not only in the complexity o...

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bioengineer.org /2 weeks ago

Unraveling Raf-MEK-ERK Pathway in Prostate Cancer

The landscape of cancer therapy has been profoundly revolutionized by clinical interventions targeting the MAPK (Mitogen-Activated Protein Kinase) pathway, a critical signaling cas...

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journals.plos.org /4 days ago

Agent-based modeling demonstrates how target-independent processes supplement killing by antibody-drug conjugates in can...

by Melissa C. Calopiz, Jennifer J. Linderman, Greg M. Thurber Antibody-drug conjugates (ADCs) have had remarkable clinical success in recent years with multiple new approvals. How...

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bioengineer.org /1 week ago

Machine Learning Pinpoints Immunotherapy Targets, Validated by Tumor Explants

In a groundbreaking advancement at the intersection of artificial intelligence and oncology, researchers have unveiled a pioneering method that harnesses machine learning to accele...

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news-medical.net /1 week ago

Polymer-based immunotherapies enhance tumor targeting and immune activation

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

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medcitynews.com /2 weeks ago

A Cancer Driven by Ultra-Rare Mutation Gets Its First FDA-Approved Therapy

Partner Therapeutics’ Bizengri is now FDA approved for treating advanced cases of cholangiocarcinoma driven by NRG1 gene fusions. Partner acquired U.S. rights to this bispecific an...

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