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rna-seqblog.com /1 month ago

scSurvival – Single-Cell Survival Analysis of Clinical Cancer Cohort Data at Cellular Resolution

RNA sequencing combined with single-cell analysis enables scSurvival to link specific tumor cell populations to patient risk, improving survival prediction and revealing drivers of...

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genengnews.com /1 month ago

New Single‑Cell Platform Tracks RNA and Protein in Immune Signaling

CIPHER‑seq is a single‑cell method that measures RNA and proteins simultaneously, exposing gaps in cytokine signaling and reducing mitochondrial stress signatures to give a clearer...

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genengnews.com /1 month ago

Machine Learning and Single-Cell Technology Combined to Drive High-Performance Cell Line Development

The collaboration brings together OneCyte's proprietary single-cell platform for high-throughput and high-speed clone selection with Kemp Proteins' molecular engineering capabiliti...

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labiotech.eu /1 month ago

AI in single-cell analysis: solving the interpretation gap

Single-cell omics is reshaping drug discovery, but turning complex data into biological insight remains slow. AI may help close the annotation gap. The post AI in single-cell analy...

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rna-seqblog.com /1 month ago

Deep learning improves analysis of single cell RNA sequencing data

RNA sequencing combined with deep learning improves identification of cell populations and key genes, enabling more accurate analysis of complex single cell datasets...

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rna-seqblog.com /2 weeks ago

SCSEQ – A web tool for analyzing single-cell RNA-seq data

SCSEQ makes single-cell RNA sequencing analysis more accessible through a web-based platform that supports preprocessing, clustering, cell type identification, and downstream biolo...

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rna-seqblog.com /1 month ago

High-quality acinar cell isolation enables single-cell analysis of healthy and injured pancreas

RNA sequencing reveals improved recovery and analysis of pancreatic acinar cells, enabling clearer insights into cell states in healthy tissue and disease conditions...

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scienceblog.com /3 weeks ago

New Method Reads a Cell’s Genes Without Killing It

Every few minutes, a living cell does something quietly extraordinary: it sheds tiny membrane bubbles into the fluid around it. These extracellular vesicles carry molecular cargo (...

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rna-seqblog.com /1 month ago

Single-cell total RNA sequencing expands our view of gene regulation

RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...

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rna-seqblog.com /1 month ago

SPTEdU-seq – parallel optics-free newborn cell tracking and spatial total transcriptional dynamics

RNA sequencing combined with spatial profiling tracks gene expression and cell proliferation, revealing dynamic cellular interactions and uncovering new insights into development.....

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rna-seqblog.com /3 days ago

TAP-seq – targeted single-cell RNA and perturbation sequencing

TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...

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journals.plos.org /3 weeks ago

scHG: A supercell framework with high-order graph learning enables scalable multi-omics analysis

by Yixiang Huang, Yuan Gan, Xinqi Gong Multi-omics profiling—spanning proteomics, transcriptomics, and additional omics data types—is rapidly advancing, providing increasingly det...

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rna-seqblog.com /2 days ago

Decima predicts gene expression at single-cell resolution

RNA sequencing from more than 22 million cells trained a model that predicts cell-type-specific gene expression and noncoding variant...

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rna-seqblog.com /1 month ago

Parse biosciences launches FFPE-compatible barcoding technology for whole transcriptome single cell analysis

Parse Biosciences enables RNA sequencing of FFPE samples at single cell resolution, unlocking archived tissues for whole transcriptome analysis and deeper insights into gene...

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rna-seqblog.com /1 month ago

PhytoCell – an ensemble learning framework for identifying cell states in plant scRNA-seq data

PhytoCell uses machine learning with RNA sequencing to identify marker genes and classify plant cell subpopulations, improving accuracy in complex single-cell datasets...

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journals.plos.org /1 month ago

Semi-parametric empirical bayes method for multiplet detection in snATAC-seq with probabilistic multi-omic integration

by Yuntian Wu, Haoran Hu, Wei Chen, Johann E. Gudjonsson, Lam C. Tsoi, Xiaoquan Wen Multiplets arise when multiple cells are captured within the same droplet during single-cell se...

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rna-seqblog.com /3 weeks ago

SCOTCH – isoform-level characterization of gene expression through long-read single-cell RNA sequencing

RNA sequencing with SCOTCH improves isoform-level analysis from long-read single-cell data, helping reveal cell-type-specific transcript diversity and novel RNA isoforms

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rna-seqblog.com /1 month ago

New sequencing method exposes hidden gaps in immune signaling

RNA sequencing combined with protein analysis enables detailed tracking of immune cell activity, revealing cytokine dynamics and improving understanding of cancer and immune respon...

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rna-seqblog.com /1 day ago

Parse Biosciences and bit.bio Announce Landmark Alliance

This Parse Biosciences and bit.bio alliance combines single-cell RNA sequencing and causal transcriptomics to map transcription factor-driven cell identity, enabling improved disea...

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scienceblog.com /1 month ago

AI Tool Reads Individual Tumor Cells to Predict Who Will Survive Cancer

Two patients walk into an oncology clinic with what looks, on paper, like the same melanoma. Same stage, same tumor size, comparable bloodwork. One lives for a decade. The other is...

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rna-seqblog.com /3 weeks ago

Statistical analysis of tissue-dynamics inferences derived from single-cell RNA-sequencing atlases

As a research assistant, you will work on a focused, well-scoped project with a clear scientific goal: bringing a single-cell tissue-dynamics analysis to publication in a leading s...

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rna-seqblog.com /1 month ago

Takara Bio USA, Inc. validates new class of spatial transcriptomics technology with benchmark study for cancer research

Takara Bio’s Trekker FX spatial transcriptomics improves single-cell resolution and detects more cell interactions, enhancing analysis of tumor microenvironments in cancer samples....

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journals.plos.org /1 month ago

STARCall integrates image stitching, alignment, and read calling to enable scalable analysis of <i>in situ</i&g...

by Nicholas J. Bradley, Sriram Pendyala, Katie Partington, Douglas M. Fowler Fluorescent in situ sequencing involves imaging-based sequencing by synthesis in intact cells or tissu...

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marktechpost.com /3 weeks ago

How to Build a Single-Cell RNA-seq Analysis Pipeline with Scanpy for PBMC Clustering, Annotation, and Trajectory Discove...

In this tutorial, we perform an advanced single-cell RNA-seq analysis workflow using Scanpy on the PBMC-3k benchmark dataset. We start by loading the dataset, inspecting its struct...

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