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rna-seqblog.com /1 month ago

CHOP researchers develop versatile and low-cost technology for targeted long-read RNA sequencing

Long-read RNA sequencing improves rare disease diagnosis by resolving transcript isoforms and variant effects, enabling more accurate interpretation of pathogenic splicing...

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rna-seqblog.com /1 month ago

Next-generation sequencing has had a huge impact on molecular pathology lab

RNA sequencing and next generation sequencing expand cancer diagnostics by enabling multi gene analysis, improving mutation detection, and supporting targeted therapy decisions in...

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rna-seqblog.com /1 month ago

Parse biosciences launches FFPE-compatible barcoding technology for whole transcriptome single cell analysis

Parse Biosciences enables RNA sequencing of FFPE samples at single cell resolution, unlocking archived tissues for whole transcriptome analysis and deeper insights into gene...

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rna-seqblog.com /1 month ago

FIRST-seq – a nanopore-based cDNA sequencing platform for RNA modification and structure profiling

RNA sequencing using nanopore technology enables detection of RNA modifications and structure at single-nucleotide resolution through reverse transcription error signatures...

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rna-seqblog.com /1 month ago

Programmable RNA detection enables multiplex virus identification

RNA sequencing advances support CRISPR-based detection methods that use kinetic signatures to identify multiple viruses and variants from RNA in a single, rapid diagnostic assay...

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rna-seqblog.com /1 week ago

Oxford Nanopore and Lonza Launch Direct RNA Sequencing Solution for GMP mRNA Quality Control

RNA sequencing combined with nanopore technology and machine learning may streamline GMP quality control testing for mRNA therapeutics within a single workflow...

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genengnews.com /1 month ago

Advancing Fully Walkaway Automation in Genomics Workflows

EMBL GeneCore plans to expand facility capacity to develop new protocols and further validate and optimize existing workflows for applications such as low-input and metagenomics sa...

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rna-seqblog.com /3 days ago

TAP-seq – targeted single-cell RNA and perturbation sequencing

TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...

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journals.plos.org /2 days ago

BINSEQ: A family of high-performance binary formats for nucleotide sequences

by Noam Teyssier, Alexander Dobin Modern genomics produces billions of sequencing records per run, which are typically stored as gzip-compressed FASTQ files. While this format is...

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rna-seqblog.com /1 month ago

Alida Biosciences launches EpiPlexÂ® Tri-Modâ„¢ service for simultaneous profiling of three key mRNA modifications

RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...

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law360.com /3 weeks ago

10x, Harvard Sue Sequencing Co. Over Biology Patents

10x Genomics Inc. and Harvard have sued Element Biosciences Inc. in Delaware federal court, accusing the San Diego sequencing company of infringing four Harvard-owned patents throu...

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rna-seqblog.com /2 weeks ago

Gel-free library preparation for next-generation RNA sequencing and small RNA quantification

RNA sequencing sensitivity improves with gel-free library preparation, reducing primer dimer artifacts and enhancing small RNA quantification from lower sample inputs...

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rna-seqblog.com /1 month ago

longcallR – SNP calling, haplotype phasing and allele-specific analysis with long RNA-seq reads

RNA sequencing with long-read technology links genetic variants to transcript structure, uncovering allele-specific splicing and previously unannotated RNA events across human samp...

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rna-seqblog.com /3 weeks ago

OHSU scientist uses advanced sequencing to develop treatments for oral infections

RNA sequencing with nanopore technology helps reveal how oral bacteria regulate genes, form biofilms, and may be targeted with more precise antimicrobial strategies...

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genengnews.com /1 month ago

Integrated Sample Preparation System Standardizes and Streamlines Pre-Analytical Workflows

The Invivoscribe PrepQuant system is assay agnostic, generating highly concentrated genomic DNA and cell free DNA (cfDNA) yields for next-generation sequencing (NGS), qPCR, and dig...

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genengnews.com /1 month ago

Building the Genome Grid

MGI Tech’s decade-long push helped turn sequencing into scalable, affordable global infrastructure. The post Building the Genome Grid appeared first on GEN - Genetic Engineering an...

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bioengineer.org /1 month ago

Whole Genome & Transcriptome Sequencing: Costing Guide

In a groundbreaking development poised to revolutionize cancer diagnostics and treatment, a newly published study from Altbürger, Menzel, Beck, and colleagues explores the intricat...

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rna-seqblog.com /1 month ago

SPTEdU-seq – parallel optics-free newborn cell tracking and spatial total transcriptional dynamics

RNA sequencing combined with spatial profiling tracks gene expression and cell proliferation, revealing dynamic cellular interactions and uncovering new insights into development.....

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rna-seqblog.com /1 month ago

RNA sequencing moves toward absolute measurement of gene expression

RNA sequencing calibration using standardized references enables absolute quantification of gene expression, improving cross-study comparisons and reducing bias across experiments...

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rna-seqblog.com /1 month ago

Children’s Hospital of Philadelphia researchers develop new RNA sequencing platform for diagnosing rare diseases

RNA sequencing using targeted long-read approaches enables detection of disease-causing variants by revealing how genetic changes disrupt full-length RNA molecules...

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bioengineer.org /1 month ago

Breakthrough in Metagenomic Software Accelerates Microbial Diversity Research

In the evolving realm of metagenomics, the ability to reconstruct individual microbial genomes from complex environmental and clinical samples stands as a transformative scientific...

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journals.plos.org /1 month ago

STARCall integrates image stitching, alignment, and read calling to enable scalable analysis of <i>in situ</i&g...

by Nicholas J. Bradley, Sriram Pendyala, Katie Partington, Douglas M. Fowler Fluorescent in situ sequencing involves imaging-based sequencing by synthesis in intact cells or tissu...

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rna-seqblog.com /1 month ago

New sequencing method exposes hidden gaps in immune signaling

RNA sequencing combined with protein analysis enables detailed tracking of immune cell activity, revealing cytokine dynamics and improving understanding of cancer and immune respon...

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rna-seqblog.com /3 weeks ago

Benchmarking nanopore RNA sequencing for m6A detection

RNA sequencing with nanopore technology improves m6A modification mapping when paired with calibrated workflows, helping reveal cell-specific RNA regulation in fibroblasts and neur...

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