Small change in RNA, big impact on innate immunity
RNA sequencing and protein interaction analyses reveal how a single nucleotide at the start of RNA can alter antiviral immune signaling and influence therapeutic RNA design...
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RNA sequencing and protein interaction analyses reveal how a single nucleotide at the start of RNA can alter antiviral immune signaling and influence therapeutic RNA design...
RNA sequencing sensitivity improves with gel-free library preparation, reducing primer dimer artifacts and enhancing small RNA quantification from lower sample inputs...
RNA sequencing reveals diverse circular RNA replicons in hot spring microbes, expanding understanding of Obelisk elements and their role in microbial ecosystems...
RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...
RNA sequencing calibration using standardized references enables absolute quantification of gene expression, improving cross-study comparisons and reducing bias across experiments...
RNA sequencing with long-read technology links genetic variants to transcript structure, uncovering allele-specific splicing and previously unannotated RNA events across human samp...
RNA sequencing enables precise mapping of RNA binding protein targets, improving detection of low-abundance interactions and advancing understanding of gene regulation...
RNA sequencing with NTVE enables repeated monitoring of gene expression in living cells, supporting time-course analysis of differentiation, perturbation responses, and cellular dy...
RNA sequencing using targeted long-read approaches enables detection of disease-causing variants by revealing how genetic changes disrupt full-length RNA molecules...
RNA sequencing with the new sm-PORE-cupine method reveals how individual RNA molecules fold and behave, offering insights into gene regulation, viral biology, and therapeutic disco...
RNA sequencing with sc-rDSeq captures diverse RNA types, revealing hidden tumor heterogeneity and drug-resistant cell populations in lung cancer...
Long-read RNA sequencing improves rare disease diagnosis by resolving transcript isoforms and variant effects, enabling more accurate interpretation of pathogenic splicing...
Necrotizing enterocolitis (NEC), a devastating gastrointestinal disease primarily affecting preterm infants, continues to challenge neonatal care with its high rates of morbidity a...
RNA sequencing using TGIRT technology reveals blood-based RNA biomarkers that may improve diagnosis and monitoring of inflammatory breast cancer through liquid biopsy...
RNA sequencing method RNAP-seq maps bacterial transcription with single-nucleotide precision, revealing lineage-specific RNA polymerase pausing and regulatory factor...
RNA sequencing combined with RNA velocity enabled prediction of disease progression, treatment response, and clinical outcomes using whole-blood gene expression patterns...
RNA sequencing advances support CRISPR-based detection methods that use kinetic signatures to identify multiple viruses and variants from RNA in a single, rapid diagnostic assay...
by Chengchao Ding, Xinyi Ashley Liu, Fushun Zhang, Saori Uematsu, Shu-Bing Qian, Yan Xiang Schlafens proteins (SLFNs) are interferon-inducible regulators of RNA metabolism that in...
RNA sequencing reveals how transposable elements drive alternative splicing and alter translation in glioblastoma, generating diverse RNA isoforms linked to cancer progression...
TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...
RNA sequencing across multiple mammalian species identified conserved gene expression signatures linked to aging, mortality, chronic disease, and lifespan-modulating...
RNA sequencing enables detection of NRG1 fusions in invasive mucinous adenocarcinoma, ensuring accurate molecular profiling and identification of actionable targets often missed by...
RNA sequencing enhances detection of cancer in bile duct strictures, improving diagnostic sensitivity and enabling identification of actionable mutations for better clinical decisi...
RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...
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