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In recent years, the concept of “junk DNA” has undergone a dramatic transformation in the field of cancer biology, shifting from perceived biological detritus to a treasure trove o...
by Debomita Chakraborty, Raghunathan Rengaswamy, Karthik Raman A unique balance of seemingly contradictory properties like robustness and plasticity, or evolvability and functiona...
RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...
Typically, the information encoded in DNA allows organisms to develop, function, and pass traits across generations. Yet DNA alone does not explain how genes are switched on and of...
While 3' UTRs have traditionally been dismissed as key regulators, a new study shows that these highly conserved mRNA tails facilitate the folding of intrinsically disordered prote...
New single-cell method maps protein-DNA interactions, revealing gene regulation changes and advancing multi-omics studies of health and disease.
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