Search results for Molecular Profiling

Next-generation sequencing has had a huge impact on molecular pathology lab

RNA sequencing and next generation sequencing expand cancer diagnostics by enabling multi gene analysis, improving mutation detection, and supporting targeted therapy decisions in...

Bostongene RNA transcriptome profiling reveals new ADC targets in advanced solid tumor

RNA sequencing combined with multiomic analysis uncovers new therapeutic targets in advanced cancers, enabling identification of antibody drug conjugate options when DNA testing al...

IMA histology should trigger RNA sequencing in NSCLC – here’s why

RNA sequencing enables detection of NRG1 fusions in invasive mucinous adenocarcinoma, ensuring accurate molecular profiling and identification of actionable targets often missed by...

Su1913 PANCREATIC CYST FLUID ANALYSIS AND MOLECULAR PROFILING IMPROVE SENSITIVITY FOR PREDICTING MALIGNANCY COMPARED TO...

Detecting Disease at Its Molecular Origin

New screening technologies from Garage Brain Science aim to identify abnormal protein signals years before clinical symptoms develop. The post Detecting Disease at Its Molecular Or...

Medgenome unveils india’s first study demonstrating the clinical impact of RNA-based NGS in sarcoma diagnosis

RNA sequencing improves sarcoma diagnosis by detecting gene fusions and refining classifications, enabling more accurate treatment decisions and better patient...

Molecular Profiles Guide Targeted and Immunotherapy in SCLC

Small cell lung cancer (SCLC) remains one of the most formidable challenges within oncology, not just due to its aggressive clinical course but also as a consequence of its complex...

Understanding treatment response in high-risk bladder cancer

RNA sequencing and multi-omics profiling identified four molecular subtypes of high-risk bladder cancer, helping explain differences in immunotherapy response and recurrence risk.....

Alida Biosciences launches EpiPlex® Tri-Mod™ service for simultaneous profiling of three key mRNA modifications

RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...

How MRD Testing Is Reshaping Breast Cancer Risk Assessment

New B-59 data shows circulating tumor DNA (ctDNA) and molecular residual disease (MRD) testing can better predict recurrence risk and help guide more personalized care in TNBC.

Caris Life Sciences announces launch of Caris ChromoSeq, the world’s first whole genome and whole transcriptome tumor pr...

Integrating RNA sequencing with whole genome analysis, Caris ChromoSeq delivers...

71 MOLECULAR CLASSIFICATION AND SPATIAL CHARACTERIZATION OF INTRAHEPATIC CHOLANGIOCARCINOMA

Wobble Genomics to present novel mRNA sequencing research at AACR 2026

RNA sequencing of full-length mRNA from blood supports liquid biopsy approaches for selecting antibody-drug conjugate therapies in breast cancer, improving precision treatment deci...

From microRNA discovery to molecular mechanisms: building robust miRNA workflows for cancer research

Integrated miRNA workflows connect sequencing, dPCR validation, and pathway analysis to improve cancer biomarker discovery and biological interpretation from challenging samples li...

RNA sequencing identifies blood-based biomarkers for inflammatory breast cancer

RNA sequencing using TGIRT technology reveals blood-based RNA biomarkers that may improve diagnosis and monitoring of inflammatory breast cancer through liquid biopsy...

Mapping Molecular Markers of Physical Fitness

Mapping Molecular Markers of Physical Fitness Measurements reveal cellular pathways that appear to underlie differences in physical fitness Megan Wallin-Kerth Th...

RNA sequencing of blood samples can monitor immune responses and help tailor treatment for high-risk patients.

RNA sequencing of blood samples may help predict immune response to chemoimmunotherapy and support more personalized treatment strategies for high-risk...

Abstract No. LBA15 Liquid Biopsy Detection of TP53, mGSTP1, and mRASS1Fa from Circulating Tumor DNA Improves the Non-inv...

Alpha fetoprotein (AFP) is used to screen high risk patients for hepatocellular carcinoma (HCC) but has limited sensitivity, demanding the identification of new biomarkers. This st...

Parse Biosciences and bit.bio Announce Landmark Alliance

This Parse Biosciences and bit.bio alliance combines single-cell RNA sequencing and causal transcriptomics to map transcription factor-driven cell identity, enabling improved disea...

Cell-free DNA reveals tumor-linked nucleosomal patterns

In a revolutionary breakthrough poised to redefine cancer diagnostics, researchers have unveiled a cutting-edge technique that meticulously dissects the size of cell-free DNA fragm...

New TGen Clinical Test Streamlines Multiple Myeloma Analysis, Delivering Comprehensive Results in Just 3 Days

The Translational Genomics Research Institute (TGen), a proud division of City of Hope, has unveiled a groundbreaking advancement in the field of precision oncology with the launch...

Proteins.1 Launches to Develop Single Molecule Protein Amplification Tech for Diagnostics

Proteins.1 launches to commercialize a technology enabling ultra-sensitive detection of proteins at the single-molecule level, with the aim of transforming early disease diagnostic...

Executing biomarker-driven oncology trials

Why biomarker-driven oncology trials require new thinking across patient recruitment, assay development and regulatory strategy.

Foundation Medicine links with Fulgent Genetics to offer new gene test

Roche’s Foundation Medicine has linked with Fulgent Genetics to offer a new diagnostic test that identifies a person’s genetic makeup that can determine how they metabolize and pro...