Latest updates for Long-Read Rna Sequencing

Fresh curated links around long-read RNA sequencing are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • NanoncRNA-seq – an rRNA-depleted full-length transcriptome strategy for identification of novel lncRNA isoforms
  • Benchmarking long-read RNA sequencing tools for single-cell and spatial transcriptomics
  • Long-Read Sequencing Uppsala, November 2-4, 2026

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Recent curated links from global sources. Generate one free draft from any story, then use SocialBu to schedule and refine your content calendar.

rna-seqblog.com /1 month ago

NanoncRNA-seq – an rRNA-depleted full-length transcriptome strategy for identification of novel lncRNA isoforms

A new RNA sequencing workflow using nanopore technology improves full-length lncRNA isoform discovery, revealing many previously undetected transcripts missed by conventional short...

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rna-seqblog.com /1 month ago

Benchmarking long-read RNA sequencing tools for single-cell and spatial transcriptomics

RNA sequencing benchmark compares long-read bioinformatics tools for single-cell and spatial transcriptomics, helping researchers improve isoform detection and gene...

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rna-seqblog.com /2 weeks ago

Long-Read Sequencing Uppsala, November 2-4, 2026

The LRUA26 meeting highlights advances in long-read RNA sequencing, including full-length isoform analysis, genome assembly, structural variation, epigenetics, and emerging researc...

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rna-seqblog.com /4 weeks ago

NextLongIso – a comprehensive Nextflow pipeline for multi-dimensional long-read RNA-seq analysis

NextLongIso provides a unified RNA sequencing pipeline for analyzing transcript isoforms, alternative splicing, promoter usage, and...

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rna-seqblog.com /4 weeks ago

The promise of long-read RNA-seq: reducing bias in analyses of allele imbalance

Long-read RNA sequencing combined with practical quality-control measures reduces mapping bias and improves the accuracy of allele-specific gene expression measurements...

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rna-seqblog.com /1 month ago

ISAtools improves full-length RNA isoform analysis from long-read RNA sequencing

RNA sequencing with ISAtools enables accurate reconstruction and quantification of full-length RNA isoforms while efficiently processing large PacBio sequencing datasets...

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rna-seqblog.com /3 weeks ago

Tidesurf improves RNA velocity analysis for modern single-cell RNA sequencing

Tidesurf improves RNA sequencing analysis by accurately quantifying spliced and unspliced transcripts across 3' and 5' protocols for more reliable RNA velocity estimates...

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rna-seqblog.com /1 month ago

Examining the impact of aging on critical cellular processes

Combining short- and long-read RNA sequencing reveals how aging alters gene expression, splicing, and transcription, providing new insights into the molecular processes that drive...

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rna-seqblog.com /3 weeks ago

New RNA sequencing model improves sequencing depth planning for UMI transcriptomics

RNA sequencing model NB-Lib predicts sequencing depth requirements from shallow pilot data while accounting for library complexity, amplification differences, and molecular recover...

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rna-seqblog.com /2 weeks ago

An end-to-end computational framework for “Record-seq” transcriptional recording data

A new framework adapts RNA sequencing analysis for Record-seq, improving spacer extraction, transcription-unit quantification, normalization, differential expression, and modeling...

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rna-seqblog.com /3 weeks ago

MitoClipSplice – machine learning improves RNA sequencing analysis of mitochondrial RNA processing

RNA sequencing combined with machine learning identifies mitochondrial RNA cleavage sites from soft-clipped reads, providing a new approach for investigating mitochondrial RNA...

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journals.plos.org /1 month ago

Accurate <i>de novo</i> transcription unit annotation from run-on and sequencing data

by Paul R. Munn, Jay Chia, Charles G. Danko Functional element annotations are critical tools used to provide insight into the molecular processes governing cell development, diff...

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rna-seqblog.com /1 month ago

Seq-Scope-X pushes spatial transcriptomics beyond optical resolution

RNA sequencing combined with tissue expansion enabled ultra-high-resolution spatial transcriptomics, allowing researchers to map gene activity within individual cells with...

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rna-seqblog.com /1 day ago

POND-seq enables non-destructive RNA sequencing in living cells

POND-seq enables non-destructive RNA sequencing of living cells, allowing repeated measurement of transcriptomes and RNA-binding protein interactions as cells respond to changing c...

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journals.plos.org /1 week ago

Characterization of METTL3/14-mediated m<sup>6</sup>A modification in human transcriptome using Nanopore dir...

by Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism....

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rna-seqblog.com /1 month ago

Amaranth – enhanced single-cell transcript assembly via discriminative modelling of UMI reads and internal reads

Amaranth improves transcript reconstruction from RNA sequencing data by modeling different read types, enabling more accurate isoform analysis at single-cell resolution...

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rna-seqblog.com /5 days ago

New method allows scientists to follow gene activity over time in the same cells

Live-cell RNA sequencing uses engineered virus-like particles to repeatedly sample transcriptomes without destroying cells, enabling researchers to track gene expression changes ov...

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rna-seqblog.com /2 weeks ago

PotatoRTD and TomatoRTD: comprehensive reference transcript datasets for accurate transcriptome analysis and isoform dis...

RNA sequencing and Iso-Seq improve potato and tomato transcript annotations, revealing additional isoforms and enabling more accurate analysis of gene expression and alternative sp...

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rna-seqblog.com /1 week ago

Ultrafast and reference-free sequence discovery in single-cell data

Malva enables ultrafast, reference-free searches across massive single-cell RNA sequencing datasets for mutations, splice junctions, pathogens, transcripts, and other sequence-leve...

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rna-seqblog.com /1 month ago

Nanopore RNA sequencing maps mitochondrial tRNA modifications in yeast

RNA sequencing mapped chemical modifications across yeast mitochondrial tRNAs, providing new insight into RNA maturation and mechanisms that may influence human...

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rna-seqblog.com /1 month ago

Spatial transcriptomics benchmark compares leading platforms

RNA sequencing and spatial transcriptomics were combined to benchmark leading platforms, helping researchers compare how accurately each maps gene activity within complex tissues.....

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rna-seqblog.com /4 weeks ago

Machine learning improves RNA sequencing annotation of active genes

Machine learning improves interpretation of RNA sequencing data, helping researchers accurately identify active genes, non-coding RNAs, and other transcription units...

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rna-seqblog.com /1 month ago

seq2ribo – structure-aware integration of machine learning and simulation to predict ribosome location profiles from RNA...

New computational methods combine RNA sequencing knowledge with artificial intelligence to predict ribosome behavior directly from RNA sequences, supporting mRNA design and...

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rna-seqblog.com /1 month ago

Novogene Europe Expands Single-cell Sequencing Capability at Cambridge Omics Centre

Expanded RNA sequencing services at Novogene Europe bring advanced single-cell transcriptomics, bioinformatics, and multiomics support closer to UK researchers studying complex bio...

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Sources covering Long-Read Rna Sequencing

journals.plos.org

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journals.plos.org

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rna-seqblog.com

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rna sequencing Publications bioinformatics gene expression transcriptomics Single-cell RNA sequencing alternative splicing Machine learning Spatial transcriptomics long read sequencing Analysis Pipelines RNA isoforms

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