Latest updates for Long Read Sequencing

Fresh curated links around long read sequencing are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • CHOP researchers develop versatile and low-cost technology for targeted long-read RNA sequencing
  • FIRST-seq – a nanopore-based cDNA sequencing platform for RNA modification and structure profiling
  • FUSILLI -long-read fusion detection

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rna-seqblog.com /1 month ago

CHOP researchers develop versatile and low-cost technology for targeted long-read RNA sequencing

Long-read RNA sequencing improves rare disease diagnosis by resolving transcript isoforms and variant effects, enabling more accurate interpretation of pathogenic splicing...

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rna-seqblog.com /1 month ago

FIRST-seq – a nanopore-based cDNA sequencing platform for RNA modification and structure profiling

RNA sequencing using nanopore technology enables detection of RNA modifications and structure at single-nucleotide resolution through reverse transcription error signatures...

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rna-seqblog.com /1 month ago

FUSILLI -long-read fusion detection

RNA sequencing with FUSILLI improves detection of leukemia fusion oncogenes, supporting more accurate molecular diagnosis and subtyping in pediatric B-cell acute lymphoblastic leuk...

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rna-seqblog.com /1 month ago

Children’s Hospital of Philadelphia researchers develop new RNA sequencing platform for diagnosing rare diseases

RNA sequencing using targeted long-read approaches enables detection of disease-causing variants by revealing how genetic changes disrupt full-length RNA molecules...

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rna-seqblog.com /1 month ago

A long-read RNA sequencing and polysome profiling framework reveals transposable element-driven transcript diversity

RNA sequencing reveals how transposable elements drive alternative splicing and alter translation in glioblastoma, generating diverse RNA isoforms linked to cancer progression...

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journals.plos.org /1 month ago

STARCall integrates image stitching, alignment, and read calling to enable scalable analysis of <i>in situ</i&g...

by Nicholas J. Bradley, Sriram Pendyala, Katie Partington, Douglas M. Fowler Fluorescent in situ sequencing involves imaging-based sequencing by synthesis in intact cells or tissu...

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rna-seqblog.com /1 month ago

SCOTCH – isoform-level characterization of gene expression through long-read single-cell RNA sequencing

RNA sequencing with SCOTCH improves isoform-level analysis from long-read single-cell data, helping reveal cell-type-specific transcript diversity and novel RNA isoforms

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rna-seqblog.com /3 weeks ago

Oxford Nanopore and Lonza Launch Direct RNA Sequencing Solution for GMP mRNA Quality Control

RNA sequencing combined with nanopore technology and machine learning may streamline GMP quality control testing for mRNA therapeutics within a single workflow...

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rna-seqblog.com /2 days ago

Nanopore sequencing advances pseudouridine detection in ribosomal RNA

Nanopore direct RNA sequencing enables accurate, site-specific quantification of pseudouridine modifications in human ribosomal RNA, expanding opportunities for large-scale epitran...

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journals.plos.org /1 month ago

QoALa: A comprehensive workflow for viral quasispecies diversity comparison using long-read sequencing data

by Nakarin Pamornchainavakul, Declan C. Schroeder, Kimberly VanderWaal The concept of viral quasispecies refers to a constantly mutating viral population occurring within hosts, w...

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rna-seqblog.com /1 month ago

Benchmarking nanopore RNA sequencing for m6A detection

RNA sequencing with nanopore technology improves m6A modification mapping when paired with calibrated workflows, helping reveal cell-specific RNA regulation in fibroblasts and neur...

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rna-seqblog.com /1 week ago

Long-read RNA sequencing reveals how alternative splicing shapes immune responses

Long-read RNA sequencing revealed extensive alternative splicing changes in activated human monocytes, uncovering functional isoforms that enhance immune protein production during...

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rna-seqblog.com /1 month ago

Gel-free library preparation for next-generation RNA sequencing and small RNA quantification

RNA sequencing sensitivity improves with gel-free library preparation, reducing primer dimer artifacts and enhancing small RNA quantification from lower sample inputs...

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rna-seqblog.com /1 month ago

RNA sequencing without references uncovers hidden transcriptome features

RNA sequencing using reference-free analysis uncovers novel transcripts and hidden gene features, expanding discovery beyond traditional genome-based approaches...

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rna-seqblog.com /4 days ago

New eBook | RNA-seq: A peek inside the transcriptome

This collection highlights how RNA sequencing is advancing transcriptomics research, from single-cell analysis and disease mechanisms to nanopore sequencing and AI-driven data inte...

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journals.plos.org /2 weeks ago

BINSEQ: A family of high-performance binary formats for nucleotide sequences

by Noam Teyssier, Alexander Dobin Modern genomics produces billions of sequencing records per run, which are typically stored as gzip-compressed FASTQ files. While this format is...

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rna-seqblog.com /2 weeks ago

TAP-seq – targeted single-cell RNA and perturbation sequencing

TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...

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rna-seqblog.com /1 month ago

RNA sequencing method maps RNA binding proteins with higher precision

RNA sequencing enables precise mapping of RNA binding protein targets, improving detection of low-abundance interactions and advancing understanding of gene regulation...

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rna-seqblog.com /4 weeks ago

A*STAR scientists develop new method to reveal how RNA structure influences health and disease

RNA sequencing with the new sm-PORE-cupine method reveals how individual RNA molecules fold and behave, offering insights into gene regulation, viral biology, and therapeutic disco...

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rna-seqblog.com /2 weeks ago

PANDORA-seq – a new way to assess sperm quality

PANDORA-seq revealed sperm small RNA signatures associated with motility and morphology, providing new molecular markers for assessing male fertility...

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rna-seqblog.com /1 month ago

Systematic assessment of diverse RNA modifications using nanopore direct RNA sequencing

RNA sequencing with nanopore technology reveals how diverse therapeutic RNA modifications affect signal detection, helping define current capabilities and limitations for modificat...

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rna-seqblog.com /1 month ago

Mapping bacterial transcription with RNAP-seq

RNA sequencing method RNAP-seq maps bacterial transcription with single-nucleotide precision, revealing lineage-specific RNA polymerase pausing and regulatory factor...

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rna-seqblog.com /1 month ago

OHSU scientist uses advanced sequencing to develop treatments for oral infections

RNA sequencing with nanopore technology helps reveal how oral bacteria regulate genes, form biofilms, and may be targeted with more precise antimicrobial strategies...

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rna-seqblog.com /1 week ago

Blank Bio Announces Seed Financing and Strategic Collaboration with PacBio to Advance RNA Foundation Models for Precisio...

The Blank Bio and PacBio collaboration combines long-read RNA sequencing and AI foundation models to improve biomarker discovery, patient stratification, and precision... The post...

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Sources covering Long Read Sequencing

journals.plos.org

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rna-seqblog.com

Recent coverage from public sources
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rna sequencing Publications Nanopore sequencing Workflow transcriptomics bioinformatics Direct RNA sequencing RNA Modifications Splicing and Junction Mapping alternative splicing epitranscriptomics gene regulation

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