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Researchers have discovered that a gene linked to congenital heart disease acts like an architect for the heart cell’s DNA. Losing just one copy of TBX5 can cause the genome’s care...
The children of mothers born with heart defects face a higher risk of being developmentally vulnerable, meaning they face challenges related to physical health, emotional maturity...
By studying a gene associated with congenital heart defects, scientists uncovered a mechanism showing how small reductions in protein levels can disrupt DNA’s three-dimensional str...
It is a silent genetic condition affecting millions of people, dramatically increasing the risk of heart attacks and strokes. Yet vanishingly few have ever heard of it.
Congenital heart defects are the most common birth defects in the United States. For newborns with the most severe defects—those needing lifesaving intervention—later transfer to a...
Researchers at the University of Copenhagen found that a signaling mechanism in the cells’ ‘antennae’ may help explain why some fetuses develop disease in both the heart and other...
Congenital heart disease affects approximately two in every 100 newborns globally. But why does it occur? An important part of the answer may lie in a previously unknown mechanism...
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