Latest updates for Chip-Seq

Fresh curated links around chip-seq are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • D&D‑seq Uses Base Editing to Map DNA–Protein Interactions in Single Cells
  • Semi-parametric empirical bayes method for multiplet detection in snATAC-seq with probabilistic multi-omic integration
  • TAP-seq – targeted single-cell RNA and perturbation sequencing

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Fresh articles and ideas

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genengnews.com /1 week ago

D&D‑seq Uses Base Editing to Map DNA–Protein Interactions in Single Cells

D&D‑seq uses a base editor–nanobody fusion to record DNA–protein contacts at single‑cell resolution. The method maps transcription factor and chromatin-remodeling proteins. The...

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journals.plos.org /1 month ago

Semi-parametric empirical bayes method for multiplet detection in snATAC-seq with probabilistic multi-omic integration

by Yuntian Wu, Haoran Hu, Wei Chen, Johann E. Gudjonsson, Lam C. Tsoi, Xiaoquan Wen Multiplets arise when multiple cells are captured within the same droplet during single-cell se...

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rna-seqblog.com /3 weeks ago

TAP-seq – targeted single-cell RNA and perturbation sequencing

TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...

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journals.plos.org /1 week ago

CIPHER: An end-to-end framework for designing optimized aggregated spatial transcriptomics experiments

by Zachary Hemminger, Haley De Ocampo, Fangming Xie, Zhiqian Zhai, Jingyi Jessica Li, Roy Wollman Motivation Most imaging-based spatial transcriptomics methods measure individual g...

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journals.plos.org /1 month ago

STARCall integrates image stitching, alignment, and read calling to enable scalable analysis of <i>in situ</i&g...

by Nicholas J. Bradley, Sriram Pendyala, Katie Partington, Douglas M. Fowler Fluorescent in situ sequencing involves imaging-based sequencing by synthesis in intact cells or tissu...

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rna-seqblog.com /1 month ago

RNA sequencing method maps RNA binding proteins with higher precision

RNA sequencing enables precise mapping of RNA binding protein targets, improving detection of low-abundance interactions and advancing understanding of gene regulation...

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nanowerk.com /1 week ago

A breakthrough single-cell method for mapping DNA-protein interactions

New single-cell method maps protein-DNA interactions, revealing gene regulation changes and advancing multi-omics studies of health and disease.

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journals.plos.org /1 month ago

Cell type annotation for scATAC-seq via DNA large language model and graph domain adaptation

by Yan Liu, Sheng Guan, He Yan, Long-Chen Shen, Ji-Peng Qiang, Guo Wei Single-cell ATAC-seq (scATAC-seq) enables the exploration of chromatin accessibility at single-cell resoluti...

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rna-seqblog.com /2 weeks ago

Decima predicts gene expression at single-cell resolution

RNA sequencing from more than 22 million cells trained a model that predicts cell-type-specific gene expression and noncoding variant...

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rna-seqblog.com /1 month ago

Benchmarking nanopore RNA sequencing for m6A detection

RNA sequencing with nanopore technology improves m6A modification mapping when paired with calibrated workflows, helping reveal cell-specific RNA regulation in fibroblasts and neur...

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journals.plos.org /2 weeks ago

BINSEQ: A family of high-performance binary formats for nucleotide sequences

by Noam Teyssier, Alexander Dobin Modern genomics produces billions of sequencing records per run, which are typically stored as gzip-compressed FASTQ files. While this format is...

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rna-seqblog.com /1 month ago

Mapping bacterial transcription with RNAP-seq

RNA sequencing method RNAP-seq maps bacterial transcription with single-nucleotide precision, revealing lineage-specific RNA polymerase pausing and regulatory factor...

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rna-seqblog.com /1 month ago

Single-cell total RNA sequencing expands our view of gene regulation

RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...

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journals.plos.org /1 month ago

CASER: A semi-supervised model with multi-omics data integration prioritizes cancer-associated epigenetic regulator gene...

by Hao Li, Chaohuan Lin, Liyu Liu, Jie Lyu, Zhen Feng Prioritizing a reliable list of cancer-associated epigenetic regulators (cERs) is critical for cancer diagnosis and discovery...

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rna-seqblog.com /1 month ago

RNA sequencing without references uncovers hidden transcriptome features

RNA sequencing using reference-free analysis uncovers novel transcripts and hidden gene features, expanding discovery beyond traditional genome-based approaches...

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rna-seqblog.com /1 month ago

Alida Biosciences launches EpiPlex® Tri-Mod™ service for simultaneous profiling of three key mRNA modifications

RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...

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rna-seqblog.com /1 month ago

Mapping neural circuits behind singing mouse vocal behavior

RNA sequencing readers may find related sequencing-based methods valuable for mapping neural circuits that shape vocal behavior and brain connectivity across species...

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rna-seqblog.com /2 weeks ago

Parse Biosciences and bit.bio Announce Landmark Alliance

This Parse Biosciences and bit.bio alliance combines single-cell RNA sequencing and causal transcriptomics to map transcription factor-driven cell identity, enabling improved disea...

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journals.plos.org /1 month ago

scHG: A supercell framework with high-order graph learning enables scalable multi-omics analysis

by Yixiang Huang, Yuan Gan, Xinqi Gong Multi-omics profiling—spanning proteomics, transcriptomics, and additional omics data types—is rapidly advancing, providing increasingly det...

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rna-seqblog.com /4 days ago

Improving gene expression analysis with APA-seq data

A new APA-seq analysis method improves differential gene expression detection, helping researchers gain deeper insights from RNA sequencing data and alternative polyadenylation stu...

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rna-seqblog.com /1 week ago

New eBook | RNA-seq: A peek inside the transcriptome

This collection highlights how RNA sequencing is advancing transcriptomics research, from single-cell analysis and disease mechanisms to nanopore sequencing and AI-driven data inte...

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rna-seqblog.com /1 month ago

SCSEQ – A web tool for analyzing single-cell RNA-seq data

SCSEQ makes single-cell RNA sequencing analysis more accessible through a web-based platform that supports preprocessing, clustering, cell type identification, and downstream biolo...

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rna-seqblog.com /1 month ago

Gel-free library preparation for next-generation RNA sequencing and small RNA quantification

RNA sequencing sensitivity improves with gel-free library preparation, reducing primer dimer artifacts and enhancing small RNA quantification from lower sample inputs...

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rna-seqblog.com /1 month ago

A long-read RNA sequencing and polysome profiling framework reveals transposable element-driven transcript diversity

RNA sequencing reveals how transposable elements drive alternative splicing and alter translation in glioblastoma, generating diverse RNA isoforms linked to cancer progression...

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Sources covering Chip-Seq

feeds.feedburner.com

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journals.plos.org

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nanowerk.com

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rna-seqblog.com

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