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Chemotherapy has long been a workhorse against metastatic breast cancer, yet for most patients with estrogen receptor-positive (ER+) disease, the cancer eventually wins the evoluti...
A 70-year-old leukemia drug has uncovered a hidden side of how cancer cells survive chemotherapy. For more than 70 years, 6-thioguanine (6-TG) has been used to treat leukemia, yet...
Chemotherapies frequently cause cancer cells to enter senescence, but do not fully eliminate these cells. Therefore, it is useful to target these therapy-induced senescent cells wi...
Lung cancer continues to claim roughly 1.76 million lives each year, and while chemotherapy has extended survival for many patients, its impact is blunted by severe side effects an...
TUESDAY, Aug. 25, 2026 — A new approach to treating metastatic breast cancer may allow some patients to avoid chemotherapy, at least initially. In a small early-stage trial recentl...
The amount of DNA damage caused by certain chemotherapies used to effectively treat childhood cancer has been revealed, along with a hidden impact on the liver, paving the way for...
Researchers used DNA sequencing to map mutations in normal tissue from cancer patients undergoing different types of treatment. They found significant differences in the genetic mu...
Patients treated with gotistobart lived for a median 18.5 months, compared with 10 months for those given the standard-of-care chemotherapy.
A new review in Molecular Cancer maps how approved drugs from outside oncology could be repurposed, under a strict mechanism-first framework, to dismantle the four biological progr...
A comprehensive review finds that AML cells commonly overcome epigenetic drugs through compensatory chromatin and transcriptional adaptation, favoring biomarker-selected combinatio...
A new study is challenging one of the most common assumptions in the fast-growing field of biological aging research: that the different blood tests used to measure how fast a pers...
Researchers built a five-gene PANoptosis-based risk model and nomogram that predict survival, immune landscape, and treatment sensitivity in esophageal cancer patients.
A study found that psilocybin given before chemotherapy prevented the onset of nerve injury in mouse models, even after repeated treatment cycles, and also protected tumor-bearing...
A new study finds that patients with IDH-wildtype glioblastoma whose circulating monocyte counts are preserved during chemoradiotherapy survive substantially longer, with the dynam...
MONDAY, Sept. 14, 2026 — Many people afflicted by rare appendix cancers may not need post-surgical chemotherapy, new research shows. In most cases, such treatment won't prevent tum...
Targeting autophagy, the body’s natural cell recycling system, can cure gliomas in mouse models.
A DNA carrier checks several tumor clues before releasing its treatment, helping spare healthy cells and making chemotherapy work better in resistant brain tumors.
New research shows carboplatin drives the expansion of TP53-mutant blood clones far more strongly than PARP inhibitors, while inherited homologous recombination deficiency unexpect...
Peer-reviewed case report documents 90% volume reduction together with extensive necrosis — achieved without surgery or full-dose chemotherapy after gemcitabine failed SAN DIEGO, S...
Dear Colleagues, I am a Podiatrist with a special interest in Diabetes and High Risk Feet. I have also a personal connection with my local branch of the Leukaemia foundation. Th...
For decades, women diagnosed with triple-negative breast cancer have faced one of the most demanding treatment journeys in oncology, typically receiving a punishing combination of...
by Amjad Dabi, Joel S. Brown, Robert A. Gatenby, Corbin D. Jones, Daniel R. Schrider Cancers exhibit a remarkable ability to develop resistance to a range of treatments, often res...
The development of treatment resistance is one of the key challenges in modern cancer and antibiotic therapy. New therapeutic approaches aim to curb the spread of resistance throug...
By Mark Leiser From: healio.com Key takeaways: First-line anastrozole, trastuzumab, pertuzumab and palbociclib conferred a 97% clinical benefit rate in the single-arm ASPIRE trial....
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