Search results for Cell Therapy

Breakthrough in Cell Therapy Enhances Treatment for Advanced Liver Disease

A pioneering advancement in the treatment of advanced liver disease has emerged from the University of Edinburgh, offering fresh hope to patients who face dire prognoses due to cir...

CAR T Cell Therapy Biomanufactured by Cellares Infused Into First Two Patients

The scalable biomanufacturing of autologous products to supply thousands of patients per year can potentially be achieved with minimal capital investment and a low cost of goods. T...

Cellares and ProTgen Automate Manufacturing of Progenitor T-Cell Therapy for Blood Cancer

The partnership will automate manufacturing and quality control of ProT-096, ProTgen’s personalized progenitor T-cell therapy for refractory leukemia and other hematologic malignan...

Dual-Targeted CAR T Cells Beat Escape, Rejection

In a groundbreaking advancement poised to redefine the landscape of immunotherapy, researchers have unveiled a novel strategy employing allogeneic CD19 CAR T cells augmented with a...

CAR T-cell therapy takes woman from bedridden to 'perfectly fine'

A woman with three different autoimmune conditions had all of them treated simultaneously by genetically modifying her immune cells to kill off the rogue ones causing problems

Key CAR-T Cell Traits Trigger Myeloid Activation

In a groundbreaking study that could redefine the landscape of cellular immunotherapy, researchers have delved deep into the molecular and cellular dynamics underpinning CAR-T cell...

In Vivo CAR-Neutrophils Developed for Glioma Treatment

In a groundbreaking advancement poised to redefine cancer immunotherapy, researchers have surmounted one of the most formidable challenges in cell-based therapies: the direct genet...

Breakthrough in CAR T Cell Therapy: Insights from Successfully Treated AML Patients

A groundbreaking advance in the treatment of acute myeloid leukemia (AML) heralds a new era in immunotherapy, addressing a long-standing challenge of targeting cancer cells without...

Chimeric antigen receptor T-cell therapy in neurological disorders: Emerging applications, evidence, and challenges

Chimeric antigen receptor (CAR) T-cell therapy, initially developed for hematologic malignancies, engineers autologous T cells to eliminate pathogenic immune populations and aims t...

NPPA Gene Therapy to Encourage Greater Regeneration Following Heart Attack

Researchers here describe a novel approach to encourage greater regeneration in heart tissue following the injury and lost function incurred during a heart attack. Their work falls...

Rewriting CAR T From Within

In vivo engineering strategies promise faster, scalable cell therapies and a streamlined path from discovery to clinical development. The post Rewriting CAR T From Within appeared...

Oricell Lands $110M to Take Cell Therapy to New Territory in Cancer

There are no FDA-approved therapies for GPC3, a protein highly expressed by liver cancers. Oricell Therapeutics claims its cell therapy could be best in this class, but it faces co...

Scientists Discover Genetic “Off Switch” That Supercharges CAR T Cells Against Cancer

A new study reveals a possible way to make CAR T-cell therapy more durable and effective by targeting a single gene-regulating protein. CAR T-cell therapy is widely seen as a break...

Cytokine‑Armored CAR T Cells Overcome Antigen Heterogeneity in Glioma Model

Scientists developed a cytokine-armored CAR T-cell therapy that helps the immune system better attack aggressive brain tumors in mice, which they paired with a CAR T strategy targe...

New guidelines for identifying and treating high-risk IEC-HS patients

Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematologic malignancies, offering durable responses for patients with otherwise refractory dis...

Acute Myeloid Leukemia Therapy Improved by CRISPR Stem Cell Transplant

A Phase I/II clinical trial shows that a stem cell transplant that removes CD33 from donor cells using CRISPR can prevent cancer recurrence. The post Acute Myeloid Leukemia Therapy...

Non-Viral Large DNA Integration in Human T Cells

A groundbreaking advancement in gene editing heralds a new era for immunotherapy, addressing the longstanding challenges of integrating large DNA sequences into primary human T cel...

Cellular Intelligence acquires global rights to STEM-PD program

Cellular Intelligence has acquired global rights from Novo Nordisk to STEM-PD, an allogeneic, or donor-derived, stem cell therapy program for Parkinson’s disease. Under the terms o...

<![CDATA[How is the Role of Non-Viral Cell Engineering Technology Growing in Advanced Therapies?]]>

Regenerative Medicine: Promise, Hype, and What Actually Works

Regenerative therapy is any treatment therapy that improves tissue health or function. With that definition, we can include platelet-rich plasma (PRP), stem cells, and autologous c...

TIL therapies: the impact on cancer research

The first TIL therapy received FDA approval two years ago. What does the field look like now? The post TIL therapies: the impact on cancer research appeared first on Labiotech.eu....

Bloodlines Series: CAR T-cell Therapy Shows Promise for Smoldering Myeloma

An immunotherapy typically used in advanced stages of multiple myeloma may be effective against an early form of the disease known as smoldering myeloma—offering a potential new op...

B Cell-Targeted CAR-T Therapy Shapes Vaccine Immunity

In the rapidly evolving landscape of immunotherapy, CAR-T cell therapy has emerged as a beacon of hope for treating various malignancies, particularly hematologic cancers. A ground...

Supercharging Immune Cells May Help Control HIV Long-Term

CAR-T cell therapy is already a potent treatment for certain cancers. Now, a small study is showing early promise for managing HIV.