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Scientists have long known the brain keeps refining itself after the teenage years, but the biological “why” has been hard to pinpoint. In a new mouse study from Albert Einstein Co...
Late adolescence triggers a temporary destabilization of contextual memory circuits due to the targeted remodeling of perineuronal nets (PNNs) in the retrosplenial cortex (RSP).
A new study reveals that the human brain undergoes major shifts in 3D genome architecture and gene regulation starting in midlife.
The brain swaps cell types, starting at around age 50.ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe her...
Protective mesh-like structures, called perineuronal nets, stabilize memory circuits and unexpectedly diminish during late adolescence before rebuilding in adulthood. The post Memo...
The brain has a remarkably flexible system for handling uncertainty and changing situations. Researchers found that the frontoparietal cortex constantly shifts how it communicates...
The brain does not have to deteriorate as we grow older. In fact, one recent study shows that new cell growth in the brain occurs in adults, something previously thought not to occ...
Research involving older adults in India suggests that healthier short-range brain connections may help preserve thinking abilities as gray matter declines. Two older adults can ha...
by Hui Zhang, Zorica Petrovic, Elizabeth M. Wood, Ana Cicvaric, Maayan Krispil-Alon, Vladimir Jovasevic, Kendra Parker, Thomas E. Bassett, Anna Carboncino, Anita L. Guedea, Pengfei...
A major study found that adults with depression show disrupted production of new neurons in the hippocampus, potentially weakening the brain’s ability to separate new experiences f...
Your brain may be far more adaptable over time than researchers once believed.
The research reveals widespread synaptic loss across frontal, temporal, and emotional hubs, heavily favoring the brain's left hemisphere, independent of macro-structural MRI volume...
NIH-supported findings reveal a previously unknown aspect of human brain aging that may contribute to cognitive decline and dementia risk later in life. Beginning in middle age, th...
A new study suggests that the brain may build complex behavior in much the same way engineers build sophisticated machines: by combining reusable components rather than creating an...
When Helen Fisher scanned recently rejected college students at Stony Brook, the ventral tegmental area and nucleus accumbens fired the same way they do during cocaine cravings — m...
By explicitly linking reinforcement-driven human neuroplasticity with gradient-based decoder optimization, the framework unifies biological trial-and-error learning with mathematic...
Depression was linked to stalled adult neurogenesis and widespread molecular changes in hippocampal memory circuits. A small stream of new neurons continues to appear in the adult...
A surprising stress-related signal may help the brain repair itself after injury. Researchers found that myelin-producing precursor cells rapidly release the stress hormone CRH nea...
The extracellular matrix undergoes rapid 24-hour remodeling cycles during learning, locking into place to protect mastered skills.
After analyzing brain scans of hundreds of children over almost two decades, researchers have found that the brains of smarter children develop later in life than the brains of chi...
Rehabilitation following a stroke that causes significant loss of function is a slow, painful, and uncertain process. The concept underlying these efforts is that the brain will at...
Your brain may have brief windows when it is primed to transform a passing moment into a lasting memory. Researchers at the University of Tübingen found that natural shifts in aler...
It changes over time.ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.
A new study finds sharp contrasts between brain changes in menopause and those during pregnancy and puberty
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