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TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...
A new APA-seq analysis method improves differential gene expression detection, helping researchers gain deeper insights from RNA sequencing data and alternative polyadenylation stu...
Amaranth improves transcript reconstruction from RNA sequencing data by modeling different read types, enabling more accurate isoform analysis at single-cell resolution...
by Araf Mahmud, Chen Huang Alternative splicing affects 95% of multi-exon genes, generating protein isoforms with distinct functions. While current alternative splicing analyses e...
MERCURIUSâ„¢ 1536 DRUG-seq brings RNA sequencing to large-scale compound screening, enabling efficient gene expression profiling... The post Alithea Genomics launches early access...
by Zachary Hemminger, Haley De Ocampo, Fangming Xie, Zhiqian Zhai, Jingyi Jessica Li, Roy Wollman Motivation Most imaging-based spatial transcriptomics methods measure individual g...
STAMP combines imaging and RNA sequencing to link cell morphology with gene expression, enabling researchers to connect molecular profiles directly to observable cellular... The po...
RNA sequencing supports space biology research by enabling transcriptome-wide analysis of gene expression changes associated with spaceflight and adaptation to space environments.....
by Noam Teyssier, Alexander Dobin Modern genomics produces billions of sequencing records per run, which are typically stored as gzip-compressed FASTQ files. While this format is...
by Chengze Shen, Eleanor Wedell, Mihai Pop, Tandy Warnow In this study, we present TIPP-SD (i.e., TIPP for Species Detection), a new technique for species detection in a microbiom...
A new RNA sequencing workflow using nanopore technology improves full-length lncRNA isoform discovery, revealing many previously undetected transcripts missed by conventional short...
RNA sequencing combined with the ChiTaRS platform improves detection of disease associated chimeric RNAs, supporting biomarker discovery, liquid biopsy, and precision medicine...
D&D‑seq uses a base editor–nanobody fusion to record DNA–protein contacts at single‑cell resolution. The method maps transcription factor and chromatin-remodeling proteins. The...
Long-read RNA sequencing revealed extensive alternative splicing changes in activated human monocytes, uncovering functional isoforms that enhance immune protein production during...
RNA sequencing enabled comprehensive detection of clinically relevant gene fusions in acute leukemia, including rare rearrangements that conventional diagnostic methods failed to i...
STGBench generates realistic paired DNA and RNA sequencing datasets with known genetic alterations, enabling accurate benchmarking of spatial genomics and transcriptomics analysis....
RNA sequencing from more than 22 million cells trained a model that predicts cell-type-specific gene expression and noncoding variant...
RNA sequencing using nanopore direct RNA sequencing enables simultaneous analysis of native RNA molecules, transcript isoforms, RNA modifications, and poly(A) tails for comprehensi...
This collection highlights how RNA sequencing is advancing transcriptomics research, from single-cell analysis and disease mechanisms to nanopore sequencing and AI-driven data inte...
RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...
PANDORA-seq revealed sperm small RNA signatures associated with motility and morphology, providing new molecular markers for assessing male fertility...
RNA sequencing workflows using preserved cells enable flexible sample collection and support reproducible single-cell analyses across multiple laboratories and processing platforms...
Eclipse Bioinnovations uses RNA sequencing in eSENSE Breakâ„¢ to map RNA fragmentation at single-nucleotide resolution, helping developers understand RNA stability and structural v...
This Parse Biosciences and bit.bio alliance combines single-cell RNA sequencing and causal transcriptomics to map transcription factor-driven cell identity, enabling improved disea...
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