Latest updates for Spatial Transcriptomics

Fresh curated links around Spatial Transcriptomics are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • The history of spatial transcriptomics at Sanger
  • SPTEdU-seq – parallel optics-free newborn cell tracking and spatial total transcriptional dynamics
  • Non-destructive transcriptomics via vesicular export

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rna-seqblog.com /1 month ago

The history of spatial transcriptomics at Sanger

At the Wellcome Sanger Institute, advances in spatial transcriptomics and RNA sequencing enable detailed mapping of gene expression and cellular interactions within complex tissues...

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rna-seqblog.com /1 month ago

SPTEdU-seq – parallel optics-free newborn cell tracking and spatial total transcriptional dynamics

RNA sequencing combined with spatial profiling tracks gene expression and cell proliferation, revealing dynamic cellular interactions and uncovering new insights into development.....

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rna-seqblog.com /3 weeks ago

Non-destructive transcriptomics via vesicular export

RNA sequencing with NTVE enables repeated monitoring of gene expression in living cells, supporting time-course analysis of differentiation, perturbation responses, and cellular dy...

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rna-seqblog.com /1 month ago

Takara Bio USA, Inc. validates new class of spatial transcriptomics technology with benchmark study for cancer research

Takara Bio’s Trekker FX spatial transcriptomics improves single-cell resolution and detects more cell interactions, enhancing analysis of tumor microenvironments in cancer samples....

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rna-seqblog.com /1 week ago

Transcriptomics in space, an RNA sequencing pipeline for space biology research

RNA sequencing supports space biology research by enabling transcriptome-wide analysis of gene expression changes associated with spaceflight and adaptation to space environments.....

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rna-seqblog.com /1 month ago

A spatial atlas of the healthy human liver reveals new insights into gene expression

RNA sequencing combined with spatial transcriptomics maps gene activity in the healthy human liver, revealing zonation patterns and early cellular changes linked to steatosis

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rna-seqblog.com /3 days ago

TAP-seq – targeted single-cell RNA and perturbation sequencing

TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...

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journals.plos.org /1 month ago

STARCall integrates image stitching, alignment, and read calling to enable scalable analysis of <i>in situ</i&g...

by Nicholas J. Bradley, Sriram Pendyala, Katie Partington, Douglas M. Fowler Fluorescent in situ sequencing involves imaging-based sequencing by synthesis in intact cells or tissu...

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rna-seqblog.com /1 month ago

Single-cell total RNA sequencing expands our view of gene regulation

RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...

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rna-seqblog.com /1 week ago

New genomic approaches uncover surprising cellular dynamics of the aging brain

Advanced RNA sequencing methods, including IRISeq and EnrichSci, uncover spatial interactions and molecular changes linked to aging in vulnerable brain cell populations...

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rna-seqblog.com /1 month ago

A long-read RNA sequencing and polysome profiling framework reveals transposable element-driven transcript diversity

RNA sequencing reveals how transposable elements drive alternative splicing and alter translation in glioblastoma, generating diverse RNA isoforms linked to cancer progression...

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rna-seqblog.com /1 month ago

RNA sequencing without references uncovers hidden transcriptome features

RNA sequencing using reference-free analysis uncovers novel transcripts and hidden gene features, expanding discovery beyond traditional genome-based approaches...

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rna-seqblog.com /1 month ago

Parse biosciences launches FFPE-compatible barcoding technology for whole transcriptome single cell analysis

Parse Biosciences enables RNA sequencing of FFPE samples at single cell resolution, unlocking archived tissues for whole transcriptome analysis and deeper insights into gene...

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rna-seqblog.com /3 weeks ago

SCOTCH – isoform-level characterization of gene expression through long-read single-cell RNA sequencing

RNA sequencing with SCOTCH improves isoform-level analysis from long-read single-cell data, helping reveal cell-type-specific transcript diversity and novel RNA isoforms

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neurosciencenews.com /2 weeks ago

Mapping Millions of Aging Brain Cells Simultaneously

By developing IRISeq and EnrichSci, researchers can now map the spatial neighborhoods of millions of aging brain cells and zoom in on rare, vulnerable populations. Their discovery...

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genengnews.com /1 month ago

New Single‑Cell Platform Tracks RNA and Protein in Immune Signaling

CIPHER‑seq is a single‑cell method that measures RNA and proteins simultaneously, exposing gaps in cytokine signaling and reducing mitochondrial stress signatures to give a clearer...

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nature.com /2 weeks ago

Glycan atlassing enables functional tracing of cell state

Nature Nanotechnology, Published online: 14 May 2026; doi:10.1038/s41565-026-02151-yMultiplexed super-resolution microscopy of DNA-barcoded lectins and metabolically incorporated u...

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rna-seqblog.com /2 days ago

Decima predicts gene expression at single-cell resolution

RNA sequencing from more than 22 million cells trained a model that predicts cell-type-specific gene expression and noncoding variant...

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rna-seqblog.com /1 day ago

Parse Biosciences and bit.bio Announce Landmark Alliance

This Parse Biosciences and bit.bio alliance combines single-cell RNA sequencing and causal transcriptomics to map transcription factor-driven cell identity, enabling improved disea...

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genengnews.com /1 month ago

Spatial Biology

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers...

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rna-seqblog.com /1 month ago

New lung cancer model reveals how tumor location shapes the immune response

RNA sequencing combined with spatial transcriptomics reveals how immune cells reorganize within lung tumors, providing deeper insight into tumor microenvironment dynamics and poten...

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rna-seqblog.com /1 month ago

CHOP researchers develop versatile and low-cost technology for targeted long-read RNA sequencing

Long-read RNA sequencing improves rare disease diagnosis by resolving transcript isoforms and variant effects, enabling more accurate interpretation of pathogenic splicing...

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rna-seqblog.com /1 month ago

Alida Biosciences launches EpiPlex® Tri-Mod™ service for simultaneous profiling of three key mRNA modifications

RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...

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journals.plos.org /1 month ago

Unveiling gene perturbation effects through gene regulatory networks inference from single-cell transcriptomic data

by Clelia Corridori, Merrit Romeike, Giorgio Nicoletti, Christa Buecker, Samir Suweis, Sandro Azaele, Graziano Martello Physiological and pathological processes are governed by ne...

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Sources covering Spatial Transcriptomics

feeds.feedburner.com

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journals.plos.org

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neurosciencenews.com

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nature.com

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rna-seqblog.com

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