Latest updates for Spatial Transcriptomics

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Recent items include:

  • StPedf: Cell trajectory inference of spatial transcriptomics via spatial proximity embedding and spatial density-adaptiv
  • Histology-informed spatial domain identification through multi-view graph convolutional networks
  • CIPHER: An end-to-end framework for designing optimized aggregated spatial transcriptomics experiments

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journals.plos.org /1 month ago

StPedf: Cell trajectory inference of spatial transcriptomics via spatial proximity embedding and spatial density-adaptiv...

by Yuan Zhang, Ziyan Sun, Zhixin Shi, Mengdi Nan, Yuhan Fu, Qing Ren, Jie Gao Spatial transcriptomics is transforming our multidimensional understanding of cellular spatial organi...

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journals.plos.org /1 month ago

Histology-informed spatial domain identification through multi-view graph convolutional networks

by Huihui Zhang, Jiaxing Chang, Zirong Li, Yue Sun, Pinli Hu, Haoxiu Wang, Hang Yang, Yonglin Ren, Xingtan Zhang, Zehua Chen, Kok Wai Wong, Haojing Shao Identifying spatial domain...

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journals.plos.org /1 month ago

CIPHER: An end-to-end framework for designing optimized aggregated spatial transcriptomics experiments

by Zachary Hemminger, Haley De Ocampo, Fangming Xie, Zhiqian Zhai, Jingyi Jessica Li, Roy Wollman Motivation Most imaging-based spatial transcriptomics methods measure individual g...

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rna-seqblog.com /1 month ago

Transcriptomics in space, an RNA sequencing pipeline for space biology research

RNA sequencing supports space biology research by enabling transcriptome-wide analysis of gene expression changes associated with spaceflight and adaptation to space environments.....

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rna-seqblog.com /1 month ago

New STAMP technology bridges single-cell genomics and cell morphology to democratize spatial biology analysis

STAMP combines imaging and RNA sequencing to link cell morphology with gene expression, enabling researchers to connect molecular profiles directly to observable cellular... The po...

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rna-seqblog.com /1 month ago

Perturb-DBiT – mapping cancer biology with spatial CRISPR screening and RNA sequencing

New spatial RNA sequencing technology links large-scale CRISPR perturbations to tumor growth, metastasis, immune responses, and complex RNA regulation within intact tissues... The...

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rna-seqblog.com /1 month ago

Study is first demonstration of gene transcription measurement in the living brain

A new blood-test platform enables noninvasive monitoring of gene expression in living tissues over time, complementing RNA sequencing approaches for studying disease progression......

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rna-seqblog.com /1 month ago

TAP-seq – targeted single-cell RNA and perturbation sequencing

TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...

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rna-seqblog.com /1 month ago

m6A-ARTR-DBiT – mapping RNA modifications across tissues with spatial m6A profiling

Spatial RNA sequencing and m6A profiling reveal how RNA modifications vary across tissues, uncovering region-specific patterns of gene regulation in developing and adult... The pos...

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bioengineer.org /2 weeks ago

Linking Single-Cell Transcriptomes to Mouse Visual Circuits

In a groundbreaking study published in Nature, researchers have unveiled sophisticated predictive models linking the complex architecture of individual neurons in the mouse primary...

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rna-seqblog.com /2 weeks ago

HistoMap reconstructs single-cell spatial profiles from bulk RNA sequencing

RNA sequencing combined with artificial intelligence reconstructed single-cell spatial organization from bulk data, revealing immune barriers that may influence colorectal cancer.....

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rna-seqblog.com /1 month ago

New genomic approaches uncover surprising cellular dynamics of the aging brain

Advanced RNA sequencing methods, including IRISeq and EnrichSci, uncover spatial interactions and molecular changes linked to aging in vulnerable brain cell populations...

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rna-seqblog.com /1 month ago

New eBook | RNA-seq: A peek inside the transcriptome

This collection highlights how RNA sequencing is advancing transcriptomics research, from single-cell analysis and disease mechanisms to nanopore sequencing and AI-driven data inte...

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rna-seqblog.com /2 weeks ago

Nanopore direct RNA sequencing expands the view of the transcriptome

RNA sequencing using nanopore direct RNA sequencing enables simultaneous analysis of native RNA molecules, transcript isoforms, RNA modifications, and poly(A) tails for comprehensi...

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rna-seqblog.com /3 weeks ago

Multisite assessment of methods for cell preservation upstream of single-cell RNA sequencing

RNA sequencing workflows using preserved cells enable flexible sample collection and support reproducible single-cell analyses across multiple laboratories and processing platforms...

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rna-seqblog.com /1 month ago

Decima predicts gene expression at single-cell resolution

RNA sequencing from more than 22 million cells trained a model that predicts cell-type-specific gene expression and noncoding variant...

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rna-seqblog.com /1 month ago

Parse Biosciences and bit.bio Announce Landmark Alliance

This Parse Biosciences and bit.bio alliance combines single-cell RNA sequencing and causal transcriptomics to map transcription factor-driven cell identity, enabling improved disea...

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rna-seqblog.com /2 weeks ago

Why Multidisciplinary Teams Matter in Translational Transcriptomics

RNA sequencing delivers its greatest clinical value when multidisciplinary teams integrate laboratory, computational, and clinical expertise to ensure findings are accurate, interp...

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rna-seqblog.com /3 weeks ago

Alithea Genomics launches early access program for MERCURIUSâ„¢ 1536 DRUG-seq, bringing transcriptomics to compound scre...

MERCURIUSâ„¢ 1536 DRUG-seq brings RNA sequencing to large-scale compound screening, enabling efficient gene expression profiling... The post Alithea Genomics launches early access...

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journals.plos.org /1 month ago

Challenges and progress in RNA velocity: Comparative analysis across multiple biological contexts

by Sarah Ancheta, Leah Dorman, Guillaume Le Treut, Abel Gurung, Greg Huber, Loïc A. Royer, Alejandro Granados, Merlin Lange Single-cell RNA sequencing is revolutionizing our under...

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journals.plos.org /3 weeks ago

Cell-type resolved transcriptional network analysis of <i>in vivo</i> cellular senescence following injury

by Alda Sabalic, Victoria Moiseeva, Andres Cisneros, Oleg Deryagin, Eusebio Perdiguero, Pura Muñoz-Cánoves, Jordi Garcia-Ojalvo Identifying the genetic correlates of complex pheno...

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rna-seqblog.com /3 days ago

Amaranth – enhanced single-cell transcript assembly via discriminative modelling of UMI reads and internal reads

Amaranth improves transcript reconstruction from RNA sequencing data by modeling different read types, enabling more accurate isoform analysis at single-cell resolution...

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rna-seqblog.com /1 day ago

STGBench – sequencing-level spatial DNA-RNA simulation for multimodal and virtual cell-oriented benchmarking of genomic...

STGBench generates realistic paired DNA and RNA sequencing datasets with known genetic alterations, enabling accurate benchmarking of spatial genomics and transcriptomics analysis....

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nanowerk.com /1 week ago

Unlocking the secrets of individual cells one molecule at a time

An improved cell analysis technique boosts sensitivity and stability, mapping lipid patterns in mouse brain tissue at 5 micrometer resolution.

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Sources covering Spatial Transcriptomics

bioengineer.org

Recent coverage from public sources
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journals.plos.org

Recent coverage from public sources
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nanowerk.com

Recent coverage from public sources
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rna-seqblog.com

Recent coverage from public sources
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