Latest updates for Separate-Seq

Fresh curated links around SEPARATE-Seq are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • Semi-parametric empirical bayes method for multiplet detection in snATAC-seq with probabilistic multi-omic integration
  • SPTEdU-seq – parallel optics-free newborn cell tracking and spatial total transcriptional dynamics
  • TAP-seq – targeted single-cell RNA and perturbation sequencing

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journals.plos.org /1 month ago

Semi-parametric empirical bayes method for multiplet detection in snATAC-seq with probabilistic multi-omic integration

by Yuntian Wu, Haoran Hu, Wei Chen, Johann E. Gudjonsson, Lam C. Tsoi, Xiaoquan Wen Multiplets arise when multiple cells are captured within the same droplet during single-cell se...

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rna-seqblog.com /1 month ago

SPTEdU-seq – parallel optics-free newborn cell tracking and spatial total transcriptional dynamics

RNA sequencing combined with spatial profiling tracks gene expression and cell proliferation, revealing dynamic cellular interactions and uncovering new insights into development.....

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rna-seqblog.com /3 days ago

TAP-seq – targeted single-cell RNA and perturbation sequencing

TAP-seq combines genome editing with targeted RNA sequencing to enable sensitive and cost-effective single-cell functional genomics screens...

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rna-seqblog.com /1 month ago

FIRST-seq – a nanopore-based cDNA sequencing platform for RNA modification and structure profiling

RNA sequencing using nanopore technology enables detection of RNA modifications and structure at single-nucleotide resolution through reverse transcription error signatures...

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rna-seqblog.com /3 weeks ago

Non-destructive transcriptomics via vesicular export

RNA sequencing with NTVE enables repeated monitoring of gene expression in living cells, supporting time-course analysis of differentiation, perturbation responses, and cellular dy...

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rna-seqblog.com /1 month ago

CHOP researchers develop versatile and low-cost technology for targeted long-read RNA sequencing

Long-read RNA sequencing improves rare disease diagnosis by resolving transcript isoforms and variant effects, enabling more accurate interpretation of pathogenic splicing...

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rna-seqblog.com /1 month ago

longcallR – SNP calling, haplotype phasing and allele-specific analysis with long RNA-seq reads

RNA sequencing with long-read technology links genetic variants to transcript structure, uncovering allele-specific splicing and previously unannotated RNA events across human samp...

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rna-seqblog.com /1 month ago

Parse biosciences launches FFPE-compatible barcoding technology for whole transcriptome single cell analysis

Parse Biosciences enables RNA sequencing of FFPE samples at single cell resolution, unlocking archived tissues for whole transcriptome analysis and deeper insights into gene...

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journals.plos.org /1 month ago

STARCall integrates image stitching, alignment, and read calling to enable scalable analysis of <i>in situ</i&g...

by Nicholas J. Bradley, Sriram Pendyala, Katie Partington, Douglas M. Fowler Fluorescent in situ sequencing involves imaging-based sequencing by synthesis in intact cells or tissu...

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rna-seqblog.com /3 weeks ago

SCOTCH – isoform-level characterization of gene expression through long-read single-cell RNA sequencing

RNA sequencing with SCOTCH improves isoform-level analysis from long-read single-cell data, helping reveal cell-type-specific transcript diversity and novel RNA isoforms

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journals.plos.org /2 days ago

BINSEQ: A family of high-performance binary formats for nucleotide sequences

by Noam Teyssier, Alexander Dobin Modern genomics produces billions of sequencing records per run, which are typically stored as gzip-compressed FASTQ files. While this format is...

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rna-seqblog.com /1 month ago

Alida Biosciences launches EpiPlex® Tri-Mod™ service for simultaneous profiling of three key mRNA modifications

RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...

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rna-seqblog.com /1 month ago

Programmable RNA detection enables multiplex virus identification

RNA sequencing advances support CRISPR-based detection methods that use kinetic signatures to identify multiple viruses and variants from RNA in a single, rapid diagnostic assay...

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rna-seqblog.com /1 month ago

RNA sequencing without references uncovers hidden transcriptome features

RNA sequencing using reference-free analysis uncovers novel transcripts and hidden gene features, expanding discovery beyond traditional genome-based approaches...

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rna-seqblog.com /1 month ago

Single-cell total RNA sequencing expands our view of gene regulation

RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...

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rna-seqblog.com /2 days ago

Decima predicts gene expression at single-cell resolution

RNA sequencing from more than 22 million cells trained a model that predicts cell-type-specific gene expression and noncoding variant...

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rna-seqblog.com /3 weeks ago

Benchmarking nanopore RNA sequencing for m6A detection

RNA sequencing with nanopore technology improves m6A modification mapping when paired with calibrated workflows, helping reveal cell-specific RNA regulation in fibroblasts and neur...

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rna-seqblog.com /2 weeks ago

A*STAR scientists develop new method to reveal how RNA structure influences health and disease

RNA sequencing with the new sm-PORE-cupine method reveals how individual RNA molecules fold and behave, offering insights into gene regulation, viral biology, and therapeutic disco...

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rna-seqblog.com /1 month ago

A long-read RNA sequencing and polysome profiling framework reveals transposable element-driven transcript diversity

RNA sequencing reveals how transposable elements drive alternative splicing and alter translation in glioblastoma, generating diverse RNA isoforms linked to cancer progression...

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rna-seqblog.com /2 weeks ago

FUSILLI -long-read fusion detection

RNA sequencing with FUSILLI improves detection of leukemia fusion oncogenes, supporting more accurate molecular diagnosis and subtyping in pediatric B-cell acute lymphoblastic leuk...

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rna-seqblog.com /2 weeks ago

Mapping bacterial transcription with RNAP-seq

RNA sequencing method RNAP-seq maps bacterial transcription with single-nucleotide precision, revealing lineage-specific RNA polymerase pausing and regulatory factor...

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rna-seqblog.com /1 month ago

A new RNA sequencing method reveals hidden diversity in drug-resistant lung cancer cells

RNA sequencing with sc-rDSeq captures diverse RNA types, revealing hidden tumor heterogeneity and drug-resistant cell populations in lung cancer...

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rna-seqblog.com /2 weeks ago

Gel-free library preparation for next-generation RNA sequencing and small RNA quantification

RNA sequencing sensitivity improves with gel-free library preparation, reducing primer dimer artifacts and enhancing small RNA quantification from lower sample inputs...

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rna-seqblog.com /1 month ago

scDecorr – feature decorrelation based representation learning enables self-supervised alignment of multiple single-cell...

RNA sequencing analysis with scDecorr improves integration of single-cell datasets by reducing noise and preserving biological signals, enabling more accurate clustering and...

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Sources covering Separate-Seq

journals.plos.org

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rna-seqblog.com

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rna sequencing Publications Workflow Nanopore sequencing bioinformatics Splicing and Junction Mapping gene regulation long read sequencing single cell analysis transcriptomics Expression and Quantification alternative splicing

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