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kevinmd.com /1 week ago

Regulatory T cell reprogramming heads to trial in 2026

Most people have heard of cancer immunotherapy by now. These treatments help a patient’s own immune system recognize and attack cancer. The best-known examples are immune checkpoin...

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journals.plos.org /4 weeks ago

A microRNA atlas of CD4<sup>+</sup> T cell subsets in experimental autoimmune encephalomyelitis identifies r...

by Carolina Cunha, Daniel Inácio, Paula Vargas Romero, Ana Teresa Pais, Catarina Pelicano, Marina Costa, Sofia Mensurado, Natacha Gonçalves-Sousa, Pedro H. Papotto, Daniel Neves, D...

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bioengineer.org /2 days ago

Dendritic cell SHP1 limits memory CD8 T cell development through TCF-1/Wnt signaling

In a discovery that could reshape how scientists think about the durability of cancer immunity, a team of researchers in China has identified an unexpected molecular brake inside d...

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scitechdaily.com /1 month ago

Cancer Cells Exploit a Hidden Immune “Off Switch”

A protein called TRAILshort may act as a central immune brake that limits T-cell responses and CAR-T therapy. Cancer cells can weaken the immune system by producing a protein that...

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multiple-sclerosis-research.org /1 month ago

Gut B cells controlling MS

Neziraj T, Pössnecker E, Wang AA, Saary P, Schumacher AM, Ingelfinger F, Mathias A, Galli E, Häfelfinger M, Zuo M, Jones S, Pantazou V, Killestein J, Schädelin S, Benkert P, Granzi...

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fightaging.org /2 weeks ago

Cytotoxic CD4+ T Cells in Aging, Both Protective and Harmful

The immune system is very complex, and immune cells exist in a continuum of states rather than being separated into clearly demarcated pigeonholes of behavior. Many of the categori...

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