Regulatory T cell reprogramming heads to trial in 2026
Most people have heard of cancer immunotherapy by now. These treatments help a patient’s own immune system recognize and attack cancer. The best-known examples are immune checkpoin...
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Most people have heard of cancer immunotherapy by now. These treatments help a patient’s own immune system recognize and attack cancer. The best-known examples are immune checkpoin...
Cancer immunotherapy is entering a more controlled and technically sophisticated phase, according to a wide-ranging collection of studies and reviews that outline how researchers a...
WASHINGTON — A combination of two immunotherapy drugs produced substantially higher rates of tumor eradication when added to chemotherapy before surgery in patients with high-risk,...
The parent of children with severe food allergies has said discovering oral immunotherapy treatment has been "life changing" for her family.
A new randomized Phase II clinical trial, OPTIM, is testing whether escalating immune therapy can improve outcomes for people with recurrent or metastatic squamous cell carcinoma o...
Researchers at Purdue University have developed a small-molecule compound that could open a new route toward cancer immunotherapy by targeting a protein that normally restrains imm...
Radiotherapy may do more than destroy cancer cells at the site of treatment: it can also alert the immune system to the tumor. Yet that alarm is often too faint, too brief, or too...
A protein known for circulating in the blood to fight infection plays a very different role when produced by cells inside tumors. A protein that emerged long before animals develop...
Houston Methodist Research Institute scientists have unveiled a biodegradable implant intended to deliver cancer-fighting immunotherapy drugs directly within tumors for prolonged p...
Among the first projects identified under the partnership is a Phase 2 extension study evaluating the safety and efficacy of IMN-003A cell therapy in adult and paediatric patients...
Advanced gastric and gastroesophageal junction cancers are receiving renewed attention after researchers reported a clinical study testing a three-part first-line treatment strateg...
Engineered a DHB prodrug-based oral nano-emulsion with enhanced bioavailability, dramatically improving the efficacy of immune checkpoint blockade therapy.
CAR T-cell therapy dramatically reduced disease activity in six people with severe rheumatoid arthritis that had resisted other treatments, with three achieving medication-free rem...
A new analysis from a large, single-centre cohort suggests that when immune checkpoint inhibitors are given can meaningfully shape outcomes for patients with advanced cancer. The s...
Prostate tumors can vanish from the immune system’s radar. Now, scientists have found a way to strip away that disguise by changing the length of a single RNA molecule. Researchers...
Tolerance Bio has vaulted into the clinic by agreeing to pay NeoImmuneTech up to $260 million for rights to a fusion protein in certain thymus-related indications in the Americas a...
A newly identified inflammatory signaling target may help weaken the protective environment surrounding pancreatic tumors and make existing treatments more effective. Pancreatic tu...
Immune Checkpoints: Expanding Roles Beyond Cancer Immunotherapy Immune checkpoints (ICs) have long been recognized as critical regulators of T-cell activity within the tumor microe...
Die eine Therapie, die Heilung gegen Krebs verspricht, gibt es nicht – aber Hoffnung, dass Immuntherapien uns ein gutes Stück nach vorn katapultieren. mehr...
About the Study: Is combined inhibition of programmed cell death 1 protein (PD-1) and lymphocyte activation gene 3 (LAG-3) added to standard neoadjuvant chemotherapy (NAC) safe and...
A new treatment is like a shot of espresso for "exhausted" immune systems. It could restore the body's defenses against cancer and infection.
With seven CAR T-cell therapies approved by the U.S. Food and Drug Administration, this innovative immunotherapy has revolutionized the treatment of blood cancers in recent years....
Several children who had aggressive recurrent brain tumors remained disease-free years after this treatment, according to an early-stage trial
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