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Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.
From infections and allergies to brain diseases and autoimmune disorders, a wave of trials offers hopeClinical trials of immunotherapies have rocketed in the past decade as researc...
Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset of patients benefit. Many solid tumors remain "cold...
In a groundbreaking advancement for the treatment of advanced and recurrent endometrial cancer, recent prolonged follow-up results from the NRG Oncology GY018 phase 3 trial have re...
Researchers are exploring whether a cancer therapy could one day offer a lasting treatment for autoimmune diseases.Researchers believe there are between 80 and 150 autoimmune disea...
By: Jasenka Piljac Zegarac, PhD From: ascopubs.org Key Points: As the use of immunotherapy for the treatment of metastatic cancers advances, challenges remain in understanding the...
In a groundbreaking advancement at the intersection of artificial intelligence and oncology, researchers have unveiled a pioneering method that harnesses machine learning to accele...
In an era where the battle against advanced thyroid carcinoma remains relentless, emerging immunotherapeutic strategies have begun to reshape the outlook for patients facing this f...
Immune checkpoint molecules have emerged as pivotal mediators in the delicate balance of immune homeostasis, orchestrating the fine line between immune activation and tolerance. Th...
In a groundbreaking stride against one of oncology’s most formidable challenges, researchers have unveiled promising clinical trial results exploring novel immunotherapeutic strate...
SUNDAY, April 19, 2026 — Immunotherapy has largely failed as a treatment for cancer of the pancreas, and researchers have zeroed in on a key reason.Pancreatic tumors reprogram imm...
In the rapidly evolving landscape of immunotherapy, CAR-T cell therapy has emerged as a beacon of hope for treating various malignancies, particularly hematologic cancers. A ground...
A short burst of immunotherapy before surgery is delivering surprisingly powerful results for a specific type of colorectal cancer. Patients in a UK-led trial who received just nin...
In a remarkable breakthrough that could reshape cellular immunotherapy and broaden our understanding of calcium signaling, researchers at Texas A&M Health have engineered genet...
In a groundbreaking study published in the renowned journal Science, researchers at St. Jude Children’s Research Hospital have unveiled a critical mechanism by which tumors suppres...
An immunotherapy typically used in advanced stages of multiple myeloma may be effective against an early form of the disease known as smoldering myeloma—offering a potential new op...
A groundbreaking advance in the treatment of acute myeloid leukemia (AML) heralds a new era in immunotherapy, addressing a long-standing challenge of targeting cancer cells without...
Injectable pembrolizumab can treat several types of cancer and can be administered in under two minutesThousands of patients across England each year will benefit from a new immuno...
Injectable pembrolizumab can treat several types of cancer and can be administered in under two minutesThousands of patients across England each year will benefit from a new immuno...
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Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematologic malignancies, offering durable responses for patients with otherwise refractory dis...
Scientists have found a way to drastically ramp up mouse immune responses to cancer along with flu and COVID-19 [1]. […]
A new metabolic mechanism describes how tumors disable immune “gatekeeper” cells in the presence of cancer. Study shows that boosting mitochondrial function in dendritic cells enha...
In this GEN webinar, Joseph Shultz (VP of technical development and manufacturing, Ottimo Pharma) and Imroz Ghangas (VP of commercial sales, Asimov) discuss strategies for achievin...
In a groundbreaking study poised to reshape therapeutic strategies against colorectal cancer, researchers have uncovered a pivotal role of circulating glycocholic acid (GCA) in mod...
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