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RNA sequencing and protein interaction analyses reveal how a single nucleotide at the start of RNA can alter antiviral immune signaling and influence therapeutic RNA design...
RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...
RNA sequencing with nanopore technology reveals how diverse therapeutic RNA modifications affect signal detection, helping define current capabilities and limitations for modificat...
The platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold. In human cell lines, ΨDNA achieved 70–95% knockdown of endogenou...
RNA sequencing and new computational tools enabled construction of a large RNA interactome atlas linking RNA-binding proteins, RNA interactions, and gene regulation...
Scientists have identified a new RNA molecule that may play a key role in improving survival in cancer patients. In a recent study published in the Proceedings of the National Acad...
Nature Nanotechnology, Published online: 29 April 2026; doi:10.1038/s41565-026-02164-7Modular RNA nanostar motifs spontaneously assemble into programmable synthetic condensates in...
RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...
In the intricate landscape of genetic regulation, the study of RNA-binding proteins is unraveling new dimensions of molecular control mechanisms pivotal for development and disease...
Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps...
RNA sequencing with nanopore technology improves m6A modification mapping when paired with calibrated workflows, helping reveal cell-specific RNA regulation in fibroblasts and neur...
Researchers have established a number of interventions in short-lived species that extend life as a result of degrading the function of a cellular component, usually the mitochondr...
A new RNA-based method creates programmable artificial organelles inside living cells, enabling customizable compartments for nanomedicine and gene engineering.
A new study introduces an innovative platform capable of accurately sizing the toxic repeat expansion mutations that drive muscular dystrophy, Huntington’s disease, and ALS.
by Kaisar Ahmad Lone, Amit Mahendra Karole, Geethanjali Ravindran, Shweta Tyagi Trimethylation of histone 3 lysine 4 (H3K4me3) is a mark of active transcription, and its regulator...
RNA sequencing with the new sm-PORE-cupine method reveals how individual RNA molecules fold and behave, offering insights into gene regulation, viral biology, and therapeutic disco...
RNA sequencing combined with deep learning enables accurate prediction of m6A sites, improving understanding of RNA modifications and gene regulation across tissues and cell types....
by Rory P. Mulloy, Danyel Evseev, Noga Sharlin, Maxwell P. Bui-Marinos, Émile Lacasse, Isabelle Dubuc, Louis Flamand, Jennifer A. Corcoran Viruses face selective pressure to evade...
A new platform based on genome-wide screening systemically identifies which genes drive or block particle assembly to engineer cells that yield more potent delivery vehicles. The...
RNA sequencing improves sarcoma diagnosis by detecting gene fusions and refining classifications, enabling more accurate treatment decisions and better patient...
RNA sequencing enables detection of NRG1 fusions in invasive mucinous adenocarcinoma, ensuring accurate molecular profiling and identification of actionable targets often missed by...
RNA sequencing enables precise mapping of RNA binding protein targets, improving detection of low-abundance interactions and advancing understanding of gene regulation...
FDA draft guidance highlights next-generation sequencing approaches for evaluating off-target effects and genomic integrity in genome editing therapies, supporting safer gene thera...
RNA sequencing of small RNAs reveals hidden mosquito viruses and immune responses, helping uncover viral diversity and mechanisms that influence disease transmission in Aedes aegyp...
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