Latest updates for Rna Modifications

Fresh curated links around RNA Modifications are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • Systematic assessment of diverse RNA modifications using nanopore direct RNA sequencing
  • Alida Biosciences launches EpiPlex® Tri-Modâ„¢ service for simultaneous profiling of three key mRNA modifications
  • Small change in RNA, big impact on innate immunity

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rna-seqblog.com /3 weeks ago

Systematic assessment of diverse RNA modifications using nanopore direct RNA sequencing

RNA sequencing with nanopore technology reveals how diverse therapeutic RNA modifications affect signal detection, helping define current capabilities and limitations for modificat...

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rna-seqblog.com /1 month ago

Alida Biosciences launches EpiPlex® Tri-Mod™ service for simultaneous profiling of three key mRNA modifications

RNA sequencing now enables simultaneous detection of multiple RNA modifications alongside gene expression, providing deeper...

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rna-seqblog.com /2 weeks ago

Small change in RNA, big impact on innate immunity

RNA sequencing and protein interaction analyses reveal how a single nucleotide at the start of RNA can alter antiviral immune signaling and influence therapeutic RNA design...

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rna-seqblog.com /1 month ago

FIRST-seq – a nanopore-based cDNA sequencing platform for RNA modification and structure profiling

RNA sequencing using nanopore technology enables detection of RNA modifications and structure at single-nucleotide resolution through reverse transcription error signatures...

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bioengineer.org /6 days ago

RBM20 Isoform Control Shapes Splicing in Health

In the intricate landscape of genetic regulation, the study of RNA-binding proteins is unraveling new dimensions of molecular control mechanisms pivotal for development and disease...

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rna-seqblog.com /3 weeks ago

Benchmarking nanopore RNA sequencing for m6A detection

RNA sequencing with nanopore technology improves m6A modification mapping when paired with calibrated workflows, helping reveal cell-specific RNA regulation in fibroblasts and neur...

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rna-seqblog.com /3 days ago

CAMP4 Therapeutics preprints pioneering study on regulatory RNA profiling and gene upregulation

RNA sequencing with regRNA Capture-seq identified thousands of regulatory RNAs and enabled new strategies to increase expression of disease-related genes using ASOs...

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rna-seqblog.com /3 weeks ago

Fusion-m6A – a lightweight hybrid deep learning framework for RNA m6A site prediction

RNA sequencing combined with deep learning enables accurate prediction of m6A sites, improving understanding of RNA modifications and gene regulation across tissues and cell types....

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news-medical.net /1 week ago

New study reveals nitric oxide’s widespread impact on genetics

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps...

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rna-seqblog.com /2 days ago

New RNA interaction atlas expands understanding of gene regulation

RNA sequencing and new computational tools enabled construction of a large RNA interactome atlas linking RNA-binding proteins, RNA interactions, and gene regulation...

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genengnews.com /2 weeks ago

DNA‑Guided CRISPR Suggests a New Direction for RNA Editing

The platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold. In human cell lines, ΨDNA achieved 70–95% knockdown of endogenou...

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journals.plos.org /1 month ago

New transcription signals in SARS-CoV-2 reshape virus–host interactions

by Isabel Sola, Sonia Zuñiga Non-spike changes driving SARS-CoV-2 fitness remain undercharacterized. Two PLOS Biology papers show that evolutionary N gene changes create a transcr...

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journals.plos.org /1 day ago

Type II tRNA cleavage by SLFN14 endoribonuclease variants linked to inherited thrombocytopenia drives global translation...

by Chengchao Ding, Xinyi Ashley Liu, Fushun Zhang, Saori Uematsu, Shu-Bing Qian, Yan Xiang Schlafens proteins (SLFNs) are interferon-inducible regulators of RNA metabolism that in...

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rna-seqblog.com /1 month ago

Single-cell total RNA sequencing expands our view of gene regulation

RNA sequencing captures both coding and noncoding RNAs at single-cell resolution, revealing complex regulatory programs and cellular identities across development and disease...

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journals.plos.org /1 week ago

The <i>Pseudomonas aeruginosa</i> ribonuclease Ribocin cleaves eukaryotic ribosomes at helix 69 to inhibit h...

by Alejandro Vasquez-Rifo, Denis Susorov, Emily H. Sholi, Gabriel Demo, Yasaman Jami, Jihui Sha, James A. Wohlschlegel, Andrei Korostelev, Victor Ambros Pseudomonas aeruginosa emp...

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scitechdaily.com /1 month ago

Surprise RNA Discovery Challenges Long-Held Beliefs About How Genes Work

Scientists have identified a new RNA molecule that may play a key role in improving survival in cancer patients. In a recent study published in the Proceedings of the National Acad...

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rna-seqblog.com /1 month ago

A long-read RNA sequencing and polysome profiling framework reveals transposable element-driven transcript diversity

RNA sequencing reveals how transposable elements drive alternative splicing and alter translation in glioblastoma, generating diverse RNA isoforms linked to cancer progression...

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rna-seqblog.com /1 month ago

RNA sequencing method maps RNA binding proteins with higher precision

RNA sequencing enables precise mapping of RNA binding protein targets, improving detection of low-abundance interactions and advancing understanding of gene regulation...

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rna-seqblog.com /1 month ago

Circular RNA replicons discovered in hot springs expand microbial diversity

RNA sequencing reveals diverse circular RNA replicons in hot spring microbes, expanding understanding of Obelisk elements and their role in microbial ecosystems...

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journals.plos.org /1 month ago

Dominance modifiers at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canoni...

by Rita A. Batista, Eléonore Durand, Monika Mörchen, Jacinthe Azevedo-Favory, Samson Simon, Manu Dubin, Vinod Kumar, Eléanore Lacoste, Corinne Cruaud, Christelle Blassiau, Matteo B...

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rna-seqblog.com /1 week ago

HELIX – a scalable model for predicting context-dependent regulation of RNA splicing and isoform usage

RNA sequencing combined with deep learning enabled HELIX to predict tissue-specific splicing patterns, transcript isoforms, and patient-specific splicing changes in cancer...

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journals.plos.org /1 month ago

The <i>pos-1</i> 3′ untranslated region governs germline specification and proliferation to ensure reproduct...

by Haik V. Varderesian, Juliet N. Utaegbulam, Hannah E. Brown, Beverly Ramirez, Melina Velcani, Sean P. Ryder During fertilization, haploid gametes combine to form a zygote. The m...

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bioengineer.org /3 weeks ago

tRNA-Derived 3′U-tRFSerTGA Signals Poor Myeloma Prognosis

In a groundbreaking study published in the British Journal of Cancer, researchers have uncovered a novel molecular player in the complex landscape of multiple myeloma pathogenesis—...

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fightaging.org /2 weeks ago

Disruption of the Integrator Responsible for RNA 3′ End Processing Slows Aging in Nematodes

Researchers have established a number of interventions in short-lived species that extend life as a result of degrading the function of a cellular component, usually the mitochondr...

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Sources covering Rna Modifications

feeds.feedburner.com

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bioengineer.org

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feeds.feedburner.com

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journals.plos.org

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journals.plos.org

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fightaging.org

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