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In “failing” this study delivered an important pain management insight for total hip arthroplasty surgeons…
Researchers have pinpointed the brain's "placebo circuit." By training the brain to release its own endorphins in the vlPAG region, they achieved broad-spectrum pain relief without...
When back pain flares up, you want fast, effective relief. So you open your medicine cabinet in search of pain medicine and then it hits you: Which over-the-counter (OTC) painkille...
The search for a safer opioid has followed pain medicine for decades. Doctors still need strong drugs for surgery, major injury, cancer pain, and severe flare-ups. Yet the same med...
Researchers have engineered a novel nitazene-based opioid, DFNZ, that provides potent pain relief without causing respiratory depression or addiction. The "superagonist" drug could...
Story at-a-glance Acetaminophen is one of the most commonly used painkillers in the world, found in countless household medicine cabinets and often taken daily for everything from...
TUESDAY, May 19, 2026 — Adding a synthetic weed-derived drug to opioid painkillers brings no relief to people with excruciating knee pain, a new study says. Neither the cannabis dr...
TUESDAY, April 21, 2026 — People prescribed gabapentinoid painkillers, such as gabapentin (Gralise, Neurontin, Gabarone, Relgaabi), gabapentin enacarbil (Horizant), or pregabalin (...
By Dr. Lynn WebsterIn Greek mythology, the goddess Panacea carried a potion that could heal any disease. It’s a seductive image, and it’s how GLP-1 drugs can start to feel as repor...
By Pat AnsonCombining a low dose of opioids with a cannabis-based medicine did not improve acute pain for people with arthritis, according to results of a small clinical study publ...
Pain relief from a placebo may come down to a real, measurable brain pathway.
By Dr. Forest TennantOver the past 1-2 years, the fatty acid palmitoylethanolamide (PEA) was found to reduce pain and inflammation. PEA occurs naturally in our bodies and in some f...
Opioids are often used to control pain following total knee arthroplasty (TKA). Opioid-sparing pain relief tools are needed in the current setting of the opioid crisis. This prospe...
These topical creams, heat therapy treatments and pain relievers can make everyday tasks a little easier.
“Women are now told if you take a couple of ibuprofen, you are fine with the pain. In reality, that is unlikely to be true,” says Professor Ben Mol, professor of Obstetrics and Gyn...
BULLSHIT OR REAL? – April 6, 2026 – “Opioid pain medications are essential for medical purposes, but can lead to addiction and overdose,” said Nora D. Volkow, M.D., director of NIH...
A publication in Nature in April 2026 reports that N-desethyl-fluornitrazene (DFNZ), a modified nitazene and µ-opioid receptor (MOR) superagonist, produced potent analgesia in rode...
By pinpointing the neural circuits and peptides behind placebo pain relief, scientists showed effects that span pain types, highlighting possible treatment approaches that could av...
Thousands of people use the medication as pain relief for conditions ranging from sporting and other injuries to period pain
By Pat AnsonThe same academic institution that helped launch a nationwide crackdown on opioid medication has a new suggestion on how to treat chronic pain: hypnosis.Researchers at...
Cattle producers who adopt pain relief for routine procedures such as castration and dehorning are overwhelmingly sticking with it, according to Queensland cattle veterinarian Tim...
Key Takeaways Cannabis products with higher THC content may offer modest short-term pain relief, though they often bring increased side effects. CBD-dominant products currently sho...
By Pat AnsonPhysical therapy, cognitive behavioral therapy (CBT), and mindfulness are often recommended as non-pharmacological treatments for chronic lower back pain. The World Hea...
Learn about resiniferatoxin, the hottest substance on Earth that is being investigated as the future of pain relief.
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