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Strong painkillers like oxycodone and fentanyl are extensively traded on the black market.
Researchers have engineered a novel nitazene-based opioid, DFNZ, that provides potent pain relief without causing respiratory depression or addiction. The "superagonist" drug could...
The search for a safer opioid has followed pain medicine for decades. Doctors still need strong drugs for surgery, major injury, cancer pain, and severe flare-ups. Yet the same med...
A newly studied opioid compound is reshaping assumptions about pain treatment and addiction risk. Researchers at the National Institutes of Health (NIH) have identified a powerful...
The drugs are 10 times more dangerous than fentanyl. They are showing up in street drugs in the South and the Midwest, and will most likely spread to other regions.
TUESDAY, April 14, 2026 — Long-term opioid prescriptions have declined dramatically in the United States, reflecting progress made against America’s opioid epidemic, a new study s...
Zware pijnstillers zoals oxycodon en morfine worden volop verhandeld op de zwarte markt, zo blijkt uit onderzoek van Zembla. Die flink verslavende opiaten, eenvoudig te scoren via...
BULLSHIT OR REAL? – April 6, 2026 – “Opioid pain medications are essential for medical purposes, but can lead to addiction and overdose,” said Nora D. Volkow, M.D., director of NIH...
By Dr. Lynn WebsterIn Greek mythology, the goddess Panacea carried a potion that could heal any disease. It’s a seductive image, and it’s how GLP-1 drugs can start to feel as repor...
While the opioid epidemic is one of the most urgent public health emergencies facing the U.S., new therapeutic approaches for treating the underlying substance use disorder have la...
A publication in Nature in April 2026 reports that N-desethyl-fluornitrazene (DFNZ), a modified nitazene and µ-opioid receptor (MOR) superagonist, produced potent analgesia in rode...
Missouri's Attorney General is taking legal action against the sale of "7-OH", a potent opioid that is being sold over the counter and is three times more powerful than morphine, w...
By Pat AnsonSuboxone isn’t the only opioid medication linked with dental decay and disease.A large study led by VA Connecticut researchers found that patients on long-term opioid t...
Osteoarthritis of the hip and knee is common and affects millions of patients[1]. Symptoms may include stiffness and loss of mobility, as well as pain. Managing pain in the nonoper...
By Pat Anson A new survey of cannabis users in Germany found a significant reduction in their use of painkillers, sleep medications, anti-depressants and other prescription drugs a...
A 21-element recovery program for children undergoing gastrointestinal surgery reduced opioid use during hospitalization by 56%, according to a large clinical trial led by Northwes...
By Dipa KamdarFor a medicine so commonly found in bathroom cabinets and high street pharmacies, codeine has a surprisingly complicated story. It sits at the intersection of pain re...
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