PulmCrit: Myth-busting pulse dose steroid for non-CNS indications
Pulse-dose methylprednisolone is common across many medical fields (defined here as giving ≧500 mg methylprednisolone daily for ≧3 days). However, providing such a high dose of st...
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Pulse-dose methylprednisolone is common across many medical fields (defined here as giving ≧500 mg methylprednisolone daily for ≧3 days). However, providing such a high dose of st...
Another MC-RCT just dropped on catheter-directed tPA for intermediate-high risk PE patients. It’s overall pretty similar to the HI-PEITHO trial (previously discussed here). I doubt...
Category: Critical Care Nursing Because parenchymal lung injury is often heterogeneous, appropriate PEEP in one region may be suboptimal in another. Optimizing PEEP is a balance be...
SCCM recently published updated guidelines on neuromuscular blockade in ARDS. The authors present five recommendations, the first being the most potentially influential on practice...
All the literature goodness for September 2026 EMCrit Project by Scott Weingart, MD FCCM.
Category: Critical Care Nursing The lung can be injured when it is stretched excessively by positive-pressure ventilation. Historically, the most well-recognized injury was alveola...
Vasopressin in septic shock has always been a controversial mystery wrapped in an enigma. I was optimistic (bullish, even) about vasopressin for much of the early 2010s. A retrospe...
Category: Critical Care Nursing Other positive-pressure ventilation regional injuries include: Pericardium (pneumopericardium), subcutaneous tissue (subcutaneous emphysema), pleura...
Category: Critical Care Nursing Ventilator-induced lung injury is often a regional phenomenon that occurs when low-resistance/high-compliance units receive a disproportionately hi...
Category: Critical Care Nursing PEEP can be detrimental. Because the tidal breath is delivered on top of the PEEP, end-inspiratory pressures are usually raised by the application o...
Category: Critical Care Nursing Because diseased lung units require higher pressures to open than to keep open, additional recruitment can sometimes be provided by the use of recru...
Category: Critical Care Nursing Mechanical ventilation complications include lung injury, cardiac compromise, oxygen toxicity and patient discomfort. Applying support requires trad...
Category: Critical Care Nursing In patients with respiratory failure on VV-ECMO, right ventricular failure can occur due to pulmonary fibrosis and increased pulmonary vascular resi...
Category: Critical Care Nursing Positive-pressure mechanical ventilatory support is an essential component in the life support of patients with respiratory failure. However, it is...
A new review in Intensive Care Medicine maps how high-flow nasal cannula, CPAP, and helmet ventilation can safely keep ARDS patients off breathing tubes—provided clinicians monitor...
Category: Critical Care Nursing Mechanically ventilated patients are at an increased risk of pulmonary infections. One reason is that the endotracheal tube impairs the cough reflex...
Category: Critical Care Nursing Mechanically ventilated patients are at an increased risk of pulmonary infections. One reason is that the ICU environment, with its heavy antibiotic...
Category: Critical Care Nursing The major goals of mechanical ventilation with positive pressure are to unload the ventilatory muscles and to optimize ventilation-perfusion matchin...
Category: Critical Care Nursing Mechanically ventilated patients are at an increased risk of pulmonary infections. The natural protective mechanism of glottic closure is compromise...
Category: Critical Care Nursing Volume repletion can be used, if appropriate, to maintain cardiac output in the setting of high intrathoracic pressure. Lung distention can increase...
Journal Feed covers duration of hypothermia post ROSC, ramping for intubation, and discharging low-risk PE patients. The post Journal Feed Weekly Wrap-Up appeared first on emDocs.
Before Tennessee attempted to execute Christa Gail Pike on September 30, 2026, she wrote something that captured an important distinction between death and dying. Pike, who was sen...
Category: Critical Care Nursing Another potential detrimental effect of PEEP is that it raises mean intrathoracic pressure, with the potential in susceptible patients to impede ven...
Category: Critical Care Nursing With ECMO in venoarterial mode, deoxygenated blood is removed from the venous system and pumped to a membrane lung, which removes carbon dioxide and...
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