Latest updates for Plos Genetics

Fresh curated links around PLOS Genetics are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • Pervasive context-dependent effects in the genetic architecture of complex and quantitative traits revealed by a powerfu
  • GPC: An expressive and tractable deep generative model for genetic variation data
  • Low-Coverage Genome Sequencing Uncovers Hidden Clonal Seed Formation in Apple Relatives

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journals.plos.org /1 month ago

Pervasive context-dependent effects in the genetic architecture of complex and quantitative traits revealed by a powerfu...

by Gareth A. Cromie, Russell S. Lo, Lauren Ames, Trey S. Morgan, Katherine Owens, Anne E. Clark, Martin S. Timour, Julee Ashmead, Michelle Tang, J. Nathan Kutz, Joshua M. Akey, Aim...

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journals.plos.org /2 weeks ago

GPC: An expressive and tractable deep generative model for genetic variation data

by Prateek Anand, Anji Liu, Meihua Dang, Boyang Fu, Xinzhu Wei, Guy Van den Broeck, Sriram Sankararaman Generative models play an important role in population genetics, being used...

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bioengineer.org /1 week ago

Low-Coverage Genome Sequencing Uncovers Hidden Clonal Seed Formation in Apple Relatives

A low-coverage whole-genome sequencing screen of USDA apple germplasm identified 17 previously unknown apomictic genotypes, offering a cheaper, faster method for detecting clonal s...

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genengnews.com /2 weeks ago

DNA Typewriter, PEtracer Map Mouse Development Through Organogenesis

Two DNA-recording systems traced cellular family trees across mouse embryogenesis, offering new insight into how organs form and when developing cells commit to specific fates. The...

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bioengineer.org /1 month ago

MHC class II beta genes analyzed in captive king penguin colony

In a finding that is already making waves among conservation geneticists and penguin enthusiasts alike, researchers in Japan have decoded the immune-system genes of one of the worl...

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journals.plos.org /1 month ago

Correction: The Janus-faced Nature of miR-22 in Hematopoiesis: Is It an Oncogenic Tumor Suppressor or Rather a Tumor-Sup...

by The PLOS Genetics Editors

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journals.plos.org /1 day ago

The role of gene regulatory evolution in weapon diversification: Insights from comparative genomics, chromatin profiling...

by Phillip L. Davidson, Isabel G. Manley, Armin P. Moczek Condition-responsive growth is a common feature of multicellular development, during which organisms integrate genetic an...

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bioengineer.org /1 month ago

Pepper Study Links Ultra-Long Centromere Haplotypes to Evolution and Domestication Traits

Pepper plants may be hiding some of their most consequential genetic variation in regions long treated as difficult, repetitive stretches of DNA. A study published in Nature Ecolog...

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genengnews.com /1 day ago

ASHG: Signals Based on Clinical Obesity Show Stronger Links to Cardiovascular Health than Those Linked to BMI

Researchers also developed a clinical obesity polygenic score that combined information from numerous genetic variants, a score that was shown to be significantly associated with B...

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journals.plos.org /1 month ago

Development of a low-coverage whole genome sequencing screen for apomixis using a diverse set of <i>Malus</i&gt...

by Charity Z. Goeckeritz, Václav Polcar, Benjamin Gutierrez, Tomáš Urfus, Alex Harkess In the past decade, plant biologists have made several major discoveries pertaining to the g...

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bioengineer.org /1 week ago

Where a Gene Sits on the Bacterial Chromosome May Shape Its Expression Through Selection

A new PLOS Genetics study finds that bacterial gene positions along the chromosome show gradients in mean and growth-dependent expression consistent with selection shaped by replic...

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botany.one /5 days ago

Science Shared: October 17

This week: Genetics dominates the most shared papers of the week

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bioengineer.org /1 month ago

Scientists characterize genetic variants across the human intrinsically disordered proteome

Variant effect prediction has entered a new phase, but one of biology’s largest blind spots remains stubbornly difficult to resolve. Computational tools have become increasingly ef...

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genengnews.com /2 weeks ago

Flicking the Switch: Five Scientists Honored at 2026 Warren Alpert Foundation Symposium for Hemoglobinopathy Research

Stuart Orkin, MD, and his former trainees Vijay Sankaran, MD, PhD, and Daniel Bauer, PhD, were joined by Swee-Lay Thein, MD, PhD, and John Tisdale, MD, both at the NIH. Their contr...

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journals.plos.org /1 month ago

Balanced DNA interpolation improves learning of genetic distance-informed embeddings in plants

by Lara M. Kösters, Kevin Karbstein, Ladislav Hodač, Laura Albreht, Elvira Sahuquillo Balbuena, Daniel Botello, Olivier Hardy, Phebian Odufuwa, Eva Pardo Otero, Aireen Phang, Manue...

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journals.plos.org /1 day ago

Meta-analysis of over 8,000 individuals from Hawai‘i and Samoa for genetic associations to cardiometabolic phenotypes

by Bryan L. Dinh, Xinran Wang, Xin Sheng, Peggy Wan, Amit Kumar Srivastava, Take Naseri, Satupa‘itea Viali, Lynne Wilkens, Loïc Le Marchand, Christopher Haiman, Daniel E. Weeks, Ch...

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journals.plos.org /2 weeks ago

HiFIseek: Gene-specific enrichment of high-impact mutations in associated genomic regions

by Rafael Riudavets Puig, Denise G. O’Mahony, Ina Skaara Brorson, Ksenia Sokolova, Vessela N. Kristensen, Anthony Mathelier Transcription is regulated through the sequence-specifi...

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botany.one /1 month ago

The End of Papaya?: What Genomics Teaches Us About Its Survival

A study of papayas in Mexican backyards reveals how hybridisation between wild and cultivated plants can boost genetic diversity while creating new challenges for conservation.

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bioengineer.org /3 weeks ago

Near-Perfect Long Reads Reveal Hidden Mosaicism Left Behind by CRISPR Gene Editing

CRISPR-Cas9 has transformed the life sciences by giving researchers a seemingly simple tool for cutting DNA at chosen locations, but a new study published in Genome Medicine delive...

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genengnews.com /1 month ago

Why Does a Particular Genetic Variant Lead to Accelerated Huntington Disease Development?

Study results suggest how a particular genetic variant can speed onset of Huntington disease motor symptoms by up to 12.5 years and accelerate clinical measures of disease progress...

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scitechdaily.com /2 weeks ago

Extreme Human Traits May Have a Simple Genetic Explanation

A study of dozens of human traits suggests that genetic architecture may shift at the extremes. People with unusually high or low cholesterol, blood glucose, body size, and other m...

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journals.plos.org /1 week ago

DipSkmer: Reference-free population genomics with diploid genome skims

by Eduardo Charvel, Homère J. Alves Monteiro, Siavash Mirarab, Vineet Bafna Ecologists and conservation biologists rely on genetic diversity as a key essential biodiversity variab...

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journals.plos.org /1 month ago

Assessing Hardy-Weinberg equilibrium in T2T-aligned 1000 genomes project

by Elika Garg, Jaffa Romain, Lei Sun, Andrew D. Paterson Quality control of markers in genome-wide association studies often includes testing for Hardy-Weinberg equilibrium (HWE)....

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journals.plos.org /1 month ago

The distribution of fitness effects of nonsynonymous mutations varies phylogenetically across animals

by Meixi Lin, Sneha Chakraborty, Carlos Eduardo G. Amorim, Sergio F. Nigenda-Morales, Annabel C. Beichman, Paulina G. Nuñez-Valencia, Jonathan C. Mah, Jacqueline A. Robinson, Chris...

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