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medicalxpress.com /3 weeks ago

New antibodies could lead to first monoclonal treatment for measles

Vanderbilt Health researchers and colleagues have isolated human monoclonal antibodies from previously infected individuals that potently neutralized the measles virus in the labor...

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multiple-sclerosis-research.org /2 weeks ago

Comparing anti-CD20

Are all anti-CD20 the same? So if you know one do you know them all? The simple and quick answer is they do the same thing. but they do it differently. Today there have been a coup...

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genengnews.com /1 month ago

Monoclonal Antibodies Targeting MMP-9 Alleviate Peripheral Neuropathy in Diabetic Mice

Scientists developed monoclonal antibodies targeting matrix metalloproteinase-9, which in a newly reported preclinical study slowed and even reversed diabetic nerve damage in mouse...

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multiple-sclerosis-research.org /1 week ago

B cell wipe out

Deplete CD20 and you get most of the the circulating cells but not the antibody secreting cells and if you deplete BCMA expressing cells you wipe out antibody secreting cells by no...

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bioengineer.org /2 weeks ago

New Antibody Targets BAMBI to Rewire Immune Cells in Psoriatic Arthritis

Spanish researchers have developed a humanized monoclonal antibody, hB101.37, that inhibits the BAMBI pseudoreceptor and rebalances T cell immunity, showing therapeutic efficacy an...

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multiple-sclerosis-research.org /1 month ago

CAR-T Made easy

Chimeric antigen receptor (CAR) therapy is away you harness the specificity potential of antibodies and the killing potential of T cells. You make T cells to express bits of an ant...

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genengnews.com /3 weeks ago

Antibody Blocks T Cell Infiltration and Limits Neurodegeneration in Alzheimer’s Mice

Researchers developed a potential antibody-based approach to reducing neurodegeneration in tauopathies, with studies showing that in a mouse Alzheimer’s model anti-CXCR3-treated an...

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multiple-sclerosis-research.org /1 month ago

To be precise: Anti-CD20 Tx

What does a personalised biomarker in anti-CD20 therapy need to measure? CoI: None.

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genengnews.com /1 month ago

Bicistornic Vectors + piggyBac = Improved Antibody Cell Line Production

To produce stable cell lines for monoclonal antibody production, manufacturers typically use the piggyBac transposon system. For larger, multi-specific antibodies that have payload...

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journals.plos.org /2 weeks ago

Better antibodies, better science

by Johan Duchêne Poorly validated antibodies generate misleading results and waste research resources. Two new studies in PLOS Biology quantify the ethical costs of this issue, ex...

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