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A groundbreaking study recently published in Nature reveals that mitochondrial L-2-hydroxyglutarate (L-2-HG) functions as an intrinsic physiological signaling metabolite, reshaping...
And what you can do to support your metabolism.
In a groundbreaking study set to advance our understanding of metabolic regulation, researchers have uncovered the pivotal role played by thyrotropin-releasing hormone (TRH) neuron...
A common mechanism for reversing metabolic disease in some patients seems to be the sustained flattening of the hills and valleys of glucose and insulin. The post Why Metabolic Hea...
Neurons and glial cells utilize a specialized metabolic mechanism centered on leucine-derived acetyl-coenzyme A (AcCoA) to regulate the master growth hub, mTORC1.
The blood sugar and metabolic health market is on the rise as demand for blood sugar support grows. The blood sugar and metabolic health market is continuing to expand, with supple...
A key protein involved in fat metabolism has been found to do more than scientists once thought. Instead of just releasing fat, it helps maintain healthy fat tissue and balance in...
Changing glucose levels in the developing brain act as a metabolic switch, directing when progenitor cells divide or mature into myelin‑forming oligodendrocytes, with implications...
by Yao D. Cai, Joanna C. Chiu The circadian clock and cellular metabolism are tightly coupled to maintain homeostasis. A new study in PLOS Biology leverages metabolic tracing to r...
Researchers are uncovering how metabolism may influence the way certain cancers grow and adapt.
Despite the failure to produce any useful approach to therapy based on upregulation of sirtuin 1 expression, and an entirely unhelpful hype cycle that came and went associated with...
How does the gastrointestinal tract track a lack of protein and command the brain to swap food preferences? A new study reveals a dual-track gut-brain signaling axis triggered by p...
Cut protein from a rat’s diet and something odd happens within days. The animal starts burning more calories, not fewer. It develops an almost urgent craving for protein-rich food,...
The complex interplay between the gut microbiome and host metabolism has emerged as a focal point in contemporary biomedical research, illuminating new horizons in the understandin...
In a groundbreaking advancement poised to reshape clinical obesity management, researchers have introduced a novel biomarker-centric framework that revolutionizes patient monitorin...
Obesity is a pervasive health challenge affecting nearly 40% of the adult population in the United States, contributing significantly to the onset of numerous metabolic disorders s...
by Dania M. Malik, Pinky Kain, Seth D. Rhoades, Arjun Sengupta, Shirley L. Zhang, Annika Barber, Paula Haynes, Erna Sif Arnardottir, Allan Pack, Richard G. Kibbey, Amita Sehgal, Aa...
A new study shows that the Golgi proteins GOLPH3 and MYO18A control delivery of RTKs to the cell surface, defining signaling strength and revealing a potential vulnerability in RTK...
In a groundbreaking study set to reshape our understanding of obesity-related metabolic disorders, researchers have identified a pivotal molecular player that regulates immune cell...
In recent years, the ketogenic diet has gained widespread attention not only as a weight-loss strategy but also as a potential adjunct therapy in cancer treatment. Among the many p...
A new study identifies fructose as a unique metabolic signal, rather than just a calorie, that bypasses energy regulations to drive obesity and insulin resistance.
The fatty liver disease MASH is one of the metabolic disorders that Nula Therapeutics is pursuing. The startup’s small molecules are intended to restore the integrity of the nuclea...
Every time you swallow something fatty, your small intestine quietly releases a hormone called FGF19. It travels to your liver, taps the brakes on bile acid production, and nudges...
Researchers discover that local glucose levels act as a signal that determines when stem cells mature into myelin-producing oligodendrocytes.
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