Latest updates for Long Reads

Fresh curated links around Long Reads are collected here so marketers can spot useful updates and turn timely ideas into posts faster.

Recent items include:

  • NextLongIso – a comprehensive Nextflow pipeline for multi-dimensional long-read RNA-seq analysis
  • NanoncRNA-seq – an rRNA-depleted full-length transcriptome strategy for identification of novel lncRNA isoforms
  • Benchmarking long-read RNA sequencing tools for single-cell and spatial transcriptomics

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Fresh articles and ideas

Recent curated links from global sources. Generate one free draft from any story, then use SocialBu to schedule and refine your content calendar.

rna-seqblog.com /4 weeks ago

NextLongIso – a comprehensive Nextflow pipeline for multi-dimensional long-read RNA-seq analysis

NextLongIso provides a unified RNA sequencing pipeline for analyzing transcript isoforms, alternative splicing, promoter usage, and...

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rna-seqblog.com /1 month ago

NanoncRNA-seq – an rRNA-depleted full-length transcriptome strategy for identification of novel lncRNA isoforms

A new RNA sequencing workflow using nanopore technology improves full-length lncRNA isoform discovery, revealing many previously undetected transcripts missed by conventional short...

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rna-seqblog.com /1 month ago

Benchmarking long-read RNA sequencing tools for single-cell and spatial transcriptomics

RNA sequencing benchmark compares long-read bioinformatics tools for single-cell and spatial transcriptomics, helping researchers improve isoform detection and gene...

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rna-seqblog.com /4 weeks ago

The promise of long-read RNA-seq: reducing bias in analyses of allele imbalance

Long-read RNA sequencing combined with practical quality-control measures reduces mapping bias and improves the accuracy of allele-specific gene expression measurements...

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rna-seqblog.com /2 weeks ago

Long-Read Sequencing Uppsala, November 2-4, 2026

The LRUA26 meeting highlights advances in long-read RNA sequencing, including full-length isoform analysis, genome assembly, structural variation, epigenetics, and emerging researc...

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rna-seqblog.com /1 month ago

ISAtools improves full-length RNA isoform analysis from long-read RNA sequencing

RNA sequencing with ISAtools enables accurate reconstruction and quantification of full-length RNA isoforms while efficiently processing large PacBio sequencing datasets...

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rna-seqblog.com /1 month ago

Amaranth – enhanced single-cell transcript assembly via discriminative modelling of UMI reads and internal reads

Amaranth improves transcript reconstruction from RNA sequencing data by modeling different read types, enabling more accurate isoform analysis at single-cell resolution...

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rna-seqblog.com /3 weeks ago

Tidesurf improves RNA velocity analysis for modern single-cell RNA sequencing

Tidesurf improves RNA sequencing analysis by accurately quantifying spliced and unspliced transcripts across 3' and 5' protocols for more reliable RNA velocity estimates...

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journals.plos.org /4 weeks ago

Integrating short-read and long-read single-cell transcriptomics of pig pituitary reveals mechanisms of high-altitude hy...

by Hai Li, Xudong Wu, Hailong Huo, Xia Zhang, Yiming Guo, Wan Lin, Feidi Wen, Zhijun Zhao, Guiying Zhao, Jinlong Huo Acting as the central endocrine hub, the pituitary gland is cl...

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thejournal.ie /1 week ago

Sitdown Sunday: The crime writer who believes he has finally identified the Zodiac Killer

Settle down in a comfy chair with some of the week’s best longreads.

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rna-seqblog.com /2 weeks ago

PotatoRTD and TomatoRTD: comprehensive reference transcript datasets for accurate transcriptome analysis and isoform dis...

RNA sequencing and Iso-Seq improve potato and tomato transcript annotations, revealing additional isoforms and enabling more accurate analysis of gene expression and alternative sp...

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rna-seqblog.com /1 month ago

Examining the impact of aging on critical cellular processes

Combining short- and long-read RNA sequencing reveals how aging alters gene expression, splicing, and transcription, providing new insights into the molecular processes that drive...

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theguardian.com /1 month ago

‘Every sentence will be put under pressure’: how we make our Long Reads unputdownable

From plot twists to stunning visuals, our flagship long-form journalism can be as gripping as any beach read. To mark the publication of the summer issue of the Guardian Long Read...

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rna-seqblog.com /3 weeks ago

New RNA sequencing model improves sequencing depth planning for UMI transcriptomics

RNA sequencing model NB-Lib predicts sequencing depth requirements from shallow pilot data while accounting for library complexity, amplification differences, and molecular recover...

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rna-seqblog.com /2 weeks ago

An end-to-end computational framework for “Record-seq” transcriptional recording data

A new framework adapts RNA sequencing analysis for Record-seq, improving spacer extraction, transcription-unit quantification, normalization, differential expression, and modeling...

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abnormalreturns.com /1 week ago

Longform links: entertaining the reader

Thursdays are all about longform links on Abnormal Returns. Wherever possible, free links for premium sites are used. You can check out...

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dev.to /1 month ago

Anatomy of a Full RAG Application: Every Concept, One Self-Hosted Stack

"Chat with your documents" sounds simple. Then you build it, and you discover a good RAG system is really eight systems wearing a trench coat. I recently finished myRAG — a full...

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journals.plos.org /1 week ago

Characterization of METTL3/14-mediated m<sup>6</sup>A modification in human transcriptome using Nanopore dir...

by Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism....

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javacodegeeks.com /1 month ago

LangChain4j RAG in Java: Embedding, Chunking, and Retrieval Without the Python Envy

A practical pipeline for document ingestion, embedding, and retrieval, all on the JVM, with a Spring AI comparison for good measure. For a long time, if you wanted to build a Retri...

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rna-seqblog.com /1 week ago

Ultrafast and reference-free sequence discovery in single-cell data

Malva enables ultrafast, reference-free searches across massive single-cell RNA sequencing datasets for mutations, splice junctions, pathogens, transcripts, and other sequence-leve...

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rna-seqblog.com /1 month ago

Seq-Scope-X pushes spatial transcriptomics beyond optical resolution

RNA sequencing combined with tissue expansion enabled ultra-high-resolution spatial transcriptomics, allowing researchers to map gene activity within individual cells with...

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rna-seqblog.com /1 month ago

STGBench – sequencing-level spatial DNA-RNA simulation for multimodal and virtual cell-oriented benchmarking of genomic...

STGBench generates realistic paired DNA and RNA sequencing datasets with known genetic alterations, enabling accurate benchmarking of spatial genomics and transcriptomics analysis....

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journals.plos.org /1 month ago

Accurate <i>de novo</i> transcription unit annotation from run-on and sequencing data

by Paul R. Munn, Jay Chia, Charles G. Danko Functional element annotations are critical tools used to provide insight into the molecular processes governing cell development, diff...

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labiotech.eu /1 month ago

Roche’s new gene sequencer on the market: where do current players stand? 

Roche's AXELIOS 1 enters next generation DNA sequencing. Can it or rivals unseat Illumina's long-standing market dominance? The post Roche’s new gene sequencer on the market: where...

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Sources covering Long Reads

abnormalreturns.com

Recent coverage from public sources
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dev.to

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journals.plos.org

Recent coverage from public sources
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journals.plos.org

Recent coverage from public sources
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javacodegeeks.com

Recent coverage from public sources
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labiotech.eu

Recent coverage from public sources
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