Search results for Leukemia

Extra chromosomes may seed childhood leukemia years before disease, study suggests

B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood cells, one of the most common abnormalities is the pres...

Unraveling the evolution of leukemia in children with Down syndrome

It may be possible to identify which pre-cancerous cells will develop into a rare type of blood cancer, due to new research showing that a single genetic change drives myeloid leuk...

Decoding the Progression of Leukemia in Children with Down Syndrome

Groundbreaking research has unveiled new molecular insights that could revolutionize the way we predict and potentially treat a rare form of blood cancer predominantly affecting ch...

Inside TCF3::HLF-Positive B-ALL: Clinical and Molecular Insights

In the realm of hematologic malignancies, few subtypes have proved as enigmatic and challenging as TCF3::HLF-positive B-cell acute lymphoblastic leukemia (B-ALL). This rare and agg...

Breakthrough in CAR T Cell Therapy: Insights from Successfully Treated AML Patients

A groundbreaking advance in the treatment of acute myeloid leukemia (AML) heralds a new era in immunotherapy, addressing a long-standing challenge of targeting cancer cells without...

Leukemia Research Reactivates Silenced Gene in Mice: A Potential Breakthrough for Human Therapies

In a groundbreaking advancement that could rewrite the therapeutic landscape of acute myeloid leukemia (AML), researchers at The Jackson Laboratory (JAX) for Genomic Medicine have...

Can clonal hematopoiesis improve blood cancer screening?

On November 22, 2025, Tatiana Schlossberg, a 35-year-old journalist and the daughter of Caroline Kennedy, announced that she was dying from a rare and particularly aggressive form...

Existing Drugs Could Enhance Treatment Options for Infant Leukemia

A groundbreaking preclinical study has unveiled the potential of repurposing three clinically available drugs to target one of the most aggressive and devastating forms of childhoo...

Gentler blood cancer treatment could boost survival and quality of life

A gentler treatment for children whose leukemia has come back could boost survival and quality of life, a study led by a UCL academic has found. The new regime significantly reduce...

New approach to childhood leukaemia treatment could boost survival

Bloodlines Series: CAR T-cell Therapy Shows Promise for Smoldering Myeloma

An immunotherapy typically used in advanced stages of multiple myeloma may be effective against an early form of the disease known as smoldering myeloma—offering a potential new op...

Novel tool enables high-precision, low-cost pediatric leukemia diagnostics

Researchers have introduced a novel diagnostics method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatr...

From Bench to Bedside: How a Discovery About Menin Led to New Treatments for Acute Myeloid Leukemia

An AACR grant to study menin's structure gave researchers the 3D map they needed to produce new treatments for acute myeloid leukemia. The post From Bench to Bedside: How a Discove...

Scientists Identify Novel “Don’t Eat Me” Signal in Acute Myeloid Leukemia

In a groundbreaking discovery that challenges long-standing paradigms in cancer immunotherapy, researchers from Mass General Brigham, Dana-Farber Cancer Institute, and the Broad In...

Exploring the dynamics of a multi-Professional care approach in pediatric oncology: Insights from the Sport Therapy Proj...

Leukemia is a group of hematologic malignancies where acute lymphoblastic leukemia (ALL) stands as the most prevalent form in pediatric cases, making up 80% of diagnoses, with acut...

Acute Myeloid Leukemia Therapy Improved by CRISPR Stem Cell Transplant

A Phase I/II clinical trial shows that a stem cell transplant that removes CD33 from donor cells using CRISPR can prevent cancer recurrence. The post Acute Myeloid Leukemia Therapy...