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Some white blood cells fight infections in a wild way. Neutrophils can burst open and release their...
Inside a dendritic cell, something is being decided. The cell has just swallowed a fragment of debris from a dead tumour neighbour and is now, in a sense, reading it, translating m...
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In the absence of specialized immune cells, the nematode Caenorhabditis elegans has evolved an extraordinary network of cross-tissue signalling circuits to defend itself against pa...
In a groundbreaking study reshaping our understanding of immune interactions within the liver’s biliary system, Thomann, Hemmer, Agrawal, and colleagues have unveiled an unpreceden...
The aging of the adaptive immune system, made up of B cells and T cells, is a complex process. Broadly, the pace at which new adaptive immune cells are created declines to a tiny f...
Scientists just uncovered how the immune system’s killer cells strike cancer with microscopic precision. Cytotoxic T lymphocytes serve as the immune system’s specialized “killer” c...
by Hangyu Liao, Jun Yang, Lei Cai, Luhao Chi, Chunming Wang, Yuyan Xu, Juncheng Xie, Kunling Chen, Jingyuan Pei, Zesheng Jiang, Mingxin Pan, Liang Zhao Crosstalk between hepatocel...
In a groundbreaking study that unveils a crucial metabolic dimension in immune activation, researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identi...
Age-associated B cells are a problematic subset of the B cell population of immune cells that emerges in later life. In recent years researchers have uncovered various ways in whic...
Pancreatic Ductal Adenocarcinoma (PDAC) metastasizes early and frequently to the liver, limiting therapeutic options and resulting in poor prognosis. Neutrophils are key immune pla...
In a groundbreaking study published in the renowned journal Science, researchers at St. Jude Children’s Research Hospital have unveiled a critical mechanism by which tumors suppres...
Preclinical studies showed that activated T cells secrete DNA-containing extracellular vesicles that enter other immune and tumor cells to stimulate immune responses, boosting T ce...
A new study has suggested that T cells might retain a pro-inflammatory phenotype long after normal weight is regained following a period of […]
by Abhimanyu Kiran, Peter A. Thomason, David M. Versluis, Peggy I. Paschke, Hannah Donnelly, Luke Tweedy, Sergio Lilla, Isabel Bravo-Ferrer, Amy Shergold, Ryan Devlin, Edward W. Ro...
In a groundbreaking discovery that challenges long-standing paradigms in cancer immunotherapy, researchers from Mass General Brigham, Dana-Farber Cancer Institute, and the Broad In...
Researchers found that lowering MHC I can expose cancerous or foreign cells to CD4+ T cell attack, reshaping assumptions about immune targeting. Cancer cells are notorious for find...
Somewhere in your bloodstream, a type of white blood cell is quietly doing double duty. Monocytes are foot soldiers of the immune system, dispatched to sites of infection and infla...
Can the brain's own immune system be engineered to lock out invading cancer cells? A multidisciplinary research team is investigating new myeloid-focused strategies to prevent mela...
Researchers from the University of Bonn and University Hospital Bonn uncover vital mechanism for survival
Immune activation is the first stage of the immune response necessary to protect the body. It is accompanied by significant metabolic costs and inflammation. When immune cells are...
Scientists profiling immune activity in blood and spinal cord samples from ALS patients found inflammation patterns tied to disease subtype, progression speed, and survival, highli...
The brain’s resident immune cells, microglia, amass mutations in specific cancer-driving genes that don’t manifest as cancer, but instead may help drive Alzheimer’s disease, pointi...
St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - a...
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