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The PROPEL program aims to control gene expression through RNA structure, building logic-gated RNA therapies that switch on only where and when intended, without altering the genom...
RNA sequencing efforts from the Human RNome Project aim to build a comprehensive reference of human RNA sequences, isoforms, processing states and chemical modifications...
RNA Variant Imaging is attracting attention because it addresses a persistent blind spot in cancer diagnostics: many clinically relevant RNA isoforms, splice events, and fusion tra...
Direct RNA sequencing with DeCoRE reveals alternative RNA structures and folding dynamics at single-nucleotide resolution, providing a detailed view of transcript-level structural....
RNA sequencing reveals how naturally occurring mRNA sequences may reduce harmful RNA aggregation, offering insights into transcriptome stability and the design of mRNA therapeutics...
RiboBA improves ribosome profiling and RNA sequencing analysis by correcting experimental biases, enabling more accurate identification of hidden protein-coding regions and transla...
Short-read RNA sequencing reporting the modifications that alter protein output is starting to make epitranscriptomics indispensable for patient selection in precision medicines. T...
RNA sequencing with eSTRAND RNA QC enables simultaneous measurement of RNA identity, poly(A) tail length, capping efficiency, fragmentation hotspots, and dsRNA...
Through its entry into Lilly Gateway Labs, Rznomics officials say they plan to accelerate candidate discovery and development across its target gene database bank comprising over 2...
Eclipsebio’s eSTRAND RNA QC uses direct RNA sequencing to measure multiple RNA quality attributes, including identity, poly(A) tails...
by Jiayu Zhang, Yiran Tao, Yun Zhao, Miaomiao Lei, Yucheng Shen, Qicong Li, Chenxu Liu, Jiuyuan Bai Visualizing the spatiotemporal dynamics of native RNA molecules with single-tra...
Rather than requiring genetic modification of the viral glycoprotein, G-Link uses a modular protein adaptor to blind native VSV-G tropism and redirect delivery after vector product...
COVID-19 accelerated efforts to develop faster, more efficient ways of manufacturing high-quality RNA sequences. The post How COVID, Characterization, and Commerce Are Driving an R...
RNA sequencing identifies newly characterized Ap2N caps on human RNAs, including tRNA-derived fragments, revealing additional complexity in RNA processing and responses to oxidativ...
RNA sequencing and AI help identify tumor-specific alternative splicing events that may reveal new precision oncology targets across solid tumors...
A new framework adapts RNA sequencing analysis for Record-seq, improving spacer extraction, transcription-unit quantification, normalization, differential expression, and modeling...
by Carolyn Sangokoya, Isabella R. Rosso, Rana Ghandehari-Alavijeh, Robert Blelloch Post-transcriptional control by RNA binding proteins (RBPs) and microRNAs play central roles in...
Adding a viral protein, NoV B2, helped self-amplifying RNA overcome cellular defenses and produce more target protein without diminishing immune stimulation, potentially enabling f...
Researchers at Johns Hopkins University identified a reverse transcription artifact that can distort RNA sequencing and RT-qPCR...
RNA sequencing with Therna’s Chronos platform measures millions of RNA behaviors across diverse human cell types, creating large datasets for modeling expression, stability a...
RNA sequencing will help Villanova researchers investigate how UPF1 controls nonsense-mediated RNA decay and how cells identify defective RNAs linked to genetic disease...
A preclinical study showed how chemically enhanced suppressor tRNAs combined with a lung-targeted delivery system can restore production of a critical protein in models of cystic f...
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