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A new study demonstrates a new CAR-T cell therapy that targets the GPNMB protein found on both glioblastoma cells and tumor-supporting macrophages.
Glioblastoma remains one of the deadliest brain cancers, notorious for its resistance to standard therapy and its ability to adapt under treatment pressure. In a new viral-style sc...
A new study details a localized "NanoMesh" implant that delivers three synergistic drugs directly to the site of glioblastoma tumors.
As glioblastoma continues to challenge the medical community, the Foundation unveils a new genomic testing lab, an advancing drug pipeline, and a sharper focus on accelerating pers...
In a groundbreaking advancement for cancer immunotherapy, a team of researchers has unveiled promising results from a phase Ib clinical trial exploring personalized neoantigen-puls...
Researchers developed a potential treatment for brain cancer that uses nanofibers embedded with a combination of drugs that work in concert to target tumors.
A new study identifies an endoplasmic reticulum-localized lipid scramblase called CLPTM1L as the primary master regulator behind lipid raft formation in glioblastoma.
In an era where cancer research continually pushes the boundaries of personalized medicine, a groundbreaking study has emerged, promising newfound hope for patients suffering from...
“Being able to offer patients even a glimmer of hope is inspiring,” said Dr. Nathanson, a professor of molecular and medical pharmacology at the David Geffen School of Medicine at...
A new study demonstrates that the experimental compound BA-101 reverses chemotherapy resistance in glioblastoma.
A human brain network associated with survival in children with diffuse midline glioma (DMG), the deadliest childhood brain cancer, has been identified by UCL clinician-scientists,...
Researchers at the Institute of Environmental Medicine (IMM), Karolinska Institutet, have identified a possible mechanism behind the spread of the aggressive brain tumor diffuse mi...
Story at-a-glance Glioblastoma stands as one of the most aggressive brain cancers, with median survival ranging from just 12 to 15 months after diagnosis.1 This disease is characte...
In a groundbreaking advance that could reshape our understanding of diffuse midline glioma (DMG), researchers have unveiled the intricate synaptic gene enrichments that distinguish...
Researchers have identified a vitamin B12–based compound that appears capable of crossing the blood–brain barrier and selectively accumulating in glioblastoma tissue. For decades,...
A new clinical trial has found that a personalized vaccine to treat glioblastoma is safe and could potentially improve outcomes.
Sugar-coated lipid nanoparticles carried tumor-suppressing mRNA across the blood-brain barrier, shrinking glioblastoma tumors in mice.
Researchers present a shift in neuro-nanomedicine, reframing the "protein corona", the layer of blood proteins that coat nanoparticles, as a programmable, five-stage navigation int...
Former NBA center Jason Collins spent more than a decade in professional basketball.
Scientists developed a cytokine-armored CAR T-cell therapy that helps the immune system better attack aggressive brain tumors in mice, which they paired with a CAR T strategy targe...
A sugar-coated nanoparticle treatment helped extend survival in mice with glioblastoma. Glioblastoma is the deadliest form of brain cancer, with few effective treatment options and...
Researchers have identified a major sex-specific mechanism in glioblastoma, proving that the neurotransmitter GABA selectively reprograms granulocytic immune cells to shield tumors...
Integrated DNA and single-cell RNA sequencing reveals how recurrent IDH-mutant gliomas evolve into more aggressive, treatment-resistant tumors through genetic and cellular state ch...
Researchers report encouraging early results from a first-in-human clinical trial led by Children's National Hospital using a new T-cell immunotherapy for children and young adults...
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