Microglia actively shape glioblastoma growth and tumor spread
Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond th...
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Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond th...
Glioma is a tumor of the central nervous system that originates from glial cells, which support neurons in the brain. In the less aggressive, slow-progressing forms, gliomas are of...
Glioblastoma, the most prevalent and virulent form of malignant brain tumor in adults, continues to defy the best efforts of the medical community, with patient survival rates show...
A new study details a localized "NanoMesh" implant that delivers three synergistic drugs directly to the site of glioblastoma tumors.
Glioblastoma Multiforme (GBM) remains one of the most formidable challenges in neuro-oncology, notorious for its aggressive nature, rapid progression, and dismal prognosis. Recent...
by Lingni Zhou, Hongyu Che, Hongyan Jiang, Luxin Yin, Yongang Jiang, Yuhui Zhang, Haoran Liang, Rutong Yu, Xu Zhang, Xuejiao Liu Emerging evidence reveals the pivotal involvement...
Researchers developed a potential treatment for brain cancer that uses nanofibers embedded with a combination of drugs that work in concert to target tumors.
It’s smaller than a thumbnail. A dense, whitish square, barely a millimetre thick, laser-cut from a folded membrane of polymer fibres thinner than human hair. Under a microscope th...
A new study identifies an endoplasmic reticulum-localized lipid scramblase called CLPTM1L as the primary master regulator behind lipid raft formation in glioblastoma.
In an era where precision medicine is rapidly transforming cancer treatment paradigms, a groundbreaking study emerges, offering new hope for patients diagnosed with glioblastoma, o...
In a groundbreaking study poised to revolutionize glioblastoma treatment strategies, researchers have uncovered a novel therapeutic approach that exploits the vulnerabilities of ca...
In an era where cancer research continually pushes the boundaries of personalized medicine, a groundbreaking study has emerged, promising newfound hope for patients suffering from...
A groundbreaking breakthrough in cancer treatment has emerged from the laboratories of McMaster University, unveiling a novel therapeutic candidate that may revolutionize managemen...
A "first of its kind" personalized DNA vaccine is doubling survival rates for patients with aggressive glioblastoma. By targeting 40 unique tumor proteins, twice as many as previou...
Researchers have identified a vitamin B12–based compound that appears capable of crossing the blood–brain barrier and selectively accumulating in glioblastoma tissue. For decades,...
A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor of the central nervous system that often occurs in children.
A new clinical trial has found that a personalized vaccine to treat glioblastoma is safe and could potentially improve outcomes.
In a groundbreaking study published in the prestigious journal Cell Death Discovery, researchers have uncovered a pivotal mechanism through which low-dose tumor necrosis factor-alp...
RNA sequencing reveals a novel long non-coding RNA driving glioblastoma growth and treatment resistance, offering new targets to improve response to EGFR inhibitor therapies...
Researchers at the University of Reading have uncovered a compelling new approach to combat glioblastoma, the most aggressive and lethal form of brain cancer in adults. Their groun...
Discover how a personalized DNA vaccine trained patients’ immune systems to target their own tumors, with one participant remaining cancer-free nearly five years later.
Using Dynamic42’s human-based BBB-on-chip model, the partners will explore how differences between human and non-human BBB-biology can influence therapeutic responses, which is a m...
Former NBA center Jason Collins spent more than a decade in professional basketball.
Scientists developed a cytokine-armored CAR T-cell therapy that helps the immune system better attack aggressive brain tumors in mice, which they paired with a CAR T strategy targe...
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