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Top-down causation makes a lot more sense from a design perspective than from any reductionist, lower-levels-first approach. Source
Generations of “sociobiologists” have tried and failed to argue that genetic analysis offers the key to understanding social inequality. A new book fares no better.
A new platform based on genome-wide screening systemically identifies which genes drive or block particle assembly to engineer cells that yield more potent delivery vehicles. The...
In a groundbreaking study published in Nature, researchers have unveiled a comprehensive genetic analysis illuminating the intricacies of branched-chain amino acid (BCAA) metabolis...
Advanced non-viral gene delivery systems are expanding the range of indications and therapy modalities possible for the new generation of genetic medicines. The post Going Non-Vira...
Researchers show that gene syntax reshapes DNA supercoiling, amplifying or suppressing neighboring genes. The work uncovers a design rule that could improve the precision and behav...
Header Image Cannabis genetics is one of the least appreciated subjects in cannabis as a whole. It’s the unseen force behind every strain that ends up on dispensary menus and every...
Individuals occupying the far tails of complex health traits, such as cholesterol, blood glucose, age at menopause, and height, possess a fundamentally distinct genetic architectur...
by Janet Chan The Cartoon Guide to Genetics (Updated Edition) The cartoon guide to genetics by Larry Gonick and Mark Wheelis takes the reader through the history and explanation of...
Flagship Pioneering has formally launched Serif with an initial commitment of $50 million in financing—capital that Serif intends to use toward developing its scalable platform for...
A 2026 paper reports on an AI trained on genomic data, including data from a 2024 paper, enabling it to predict when transcription would be initiated. Source
Run an AI model across a human chromosome and what you get back looks like a seismograph readout: peaks and troughs, quiet stretches interrupted by jagged eruptions of ancient time...
Genetic research has been complicating the idea of the genome as a determinative blueprint.
Gene Synthesis 2.0 introduces upgraded codon optimization capability combining heuristic approaches with machine learning models trained on a high expression dataset that can impro...
New screening technologies from Garage Brain Science aim to identify abnormal protein signals years before clinical symptoms develop. The post Detecting Disease at Its Molecular Or...
Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers...
In an extraordinary advancement for lipidomics and genetic epidemiology, a comprehensive population-based genome-wide association study (GWAS) of plasma complex lipid species has r...
FDA draft guidance highlights next-generation sequencing approaches for evaluating off-target effects and genomic integrity in genome editing therapies, supporting safer gene thera...
by The PLOS Genetics Staff
Kathryn Paige Harden’s “Original Sin” explores the genetic roots of sin and guilt, and our attitudes toward punishment. The post Book Review: How Genetics Shapes Our Ideas About Vi...
In a pioneering advancement in the realm of ocular genetics, a study spearheaded by Flinders University has unearthed a significant genetic determinant implicated in juvenile glauc...
A GWAS involving 10,000 women has identified 10 genes linked to the most severe form of pregnancy sickness, hyperemesis gravidarum, including six new genes, which researchers say m...
Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps...
As more products reach the market, therapy developers partner with researchers and regulators to deliver N-of-1 treatments to patients. The post Top 10 Best Selling Gene Therapies...
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