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In recent years, the intricate relationship between genetic mutations and neurodegenerative diseases has captured the attention of the scientific community. Among these, Parkinson’...
In a groundbreaking study that pushes the boundaries of neurodegenerative disease research, Chakraborty and colleagues reveal how modulation of a gene known as dMyc can dramaticall...
The APOE ε4 variant heavily influences how toxic phosphorylated TDP-43 (pTDP-43) pathology migrates across the central nervous system.
Gerstmann-Sträussler-Scheinker disease (GSS) is characterized by an autosomal dominant inheritance due to mutations in the prion protein gene (PRNP) [1,2]. GSS(P105L) is a rare var...
Two amino acids. That is all that separates the APOE2 and APOE4 versions of the apolipoprotein E gene, a difference so small it seems almost irrelevant. Yet carriers of APOE2 are d...
A 32-year-old male patient with a recent history of cerebral infarction was referred for abnormal urinalysis. He had 4.7 g/24 h proteinuria, hypoalbuminemia (31.8 g/l), microscopic...
Amprion is partnering with Macquarie University in Australia to expand access to its SAAmplify-alphaSYN test, which detects abnormal alpha-synuclein protein in people with suspecte...
The pro-Alzheimer’s allele APOE4 makes hippocampal neurons in mice smaller and hyperexcitable. This effect, which resembles epilepsy and accelerated aging, can be mitigated by mani...
यसले एकैसाथ धेरै प्रकारका औषधि बोकेर लैजानसक्छ, जसले क्यान्सरले औषधिविरुद्ध विकास गर्ने प्रतिरोधी क्षमतालाई परास्त गर्न मद्दत पुग्छ ।
यसले एकैसाथ धेरै प्रकारका औषधि बोकेर लैजानसक्छ, जसले क्यान्सरले औषधिविरुद्ध विकास गर्ने प्रतिरोधी क्षमतालाई परास्त गर्न मद्दत पुग्छ ।
Duchenne muscular dystrophy (DMD) is the most common and severe muscle disorder in children, primarily affecting boys, with an incidence of 1 among 5000. This X-linked recessive di...
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