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qchron.com /1 month ago

Dizal Presents Positive NSCLC Data for Fourth-Generation EGFR TKI DZD6008 and Golidocitinib in Combination with Anti-PD-...

Oral presentation of DZD6008 demonstrated strong and durable anti-tumor activity, excellent BBB-penetrant properties, and a favorable safety profile in patients relapsed from third...

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lifespan.io /1 month ago

Neurons’ Protein Disposal Trick Offers Alzheimer’s Insights

According to a new study, a special protein disposal system, currently found only in neurons, is linked to central hallmarks of Alzheimer’s disease [1]. The membranal proteasome Al...

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medicalxpress.com /1 month ago

Creating mini-brains from stem cells reveals a new, promising treatment for a devastating childhood disease

Variants in the DHDDS gene cause a severe neurodegenerative condition, characterized by tremors, seizures, coordination and learning difficulties, usually manifesting in early chil...

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neurosciencenews.com /1 month ago

Alzheimer’s Risk Gene May Drive Aggressive ALS

The APOE ε4 variant heavily influences how toxic phosphorylated TDP-43 (pTDP-43) pathology migrates across the central nervous system.

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journals.plos.org /2 weeks ago

Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer’s disease and related dementias in a...

by Brenna Cholerton, Dana Godrich, Jeremy Pasteris, Joe Rivero, Eden R. Martin, Brian W. Kunkle, Adam C. Naj, Kara L. Hamilton-Nelson, Hui Wang, Wan-Ping Lee, Logan Dumitrescu, Tim...

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