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RNA sequencing identifies newly characterized Ap2N caps on human RNAs, including tRNA-derived fragments, revealing additional complexity in RNA processing and responses to oxidativ...
RNA sequencing data provide a real-world framework for comparing differential transcript usage methods across bulk, single-cell, spatial, long-read, and short-read transcriptomics....
Long-read RNA sequencing and APALORD reveal how alternative polyadenylation changes during neuronal differentiation and identify new patterns of RNA processing across species...
RNA sequencing and Iso-Seq improve potato and tomato transcript annotations, revealing additional isoforms and enabling more accurate analysis of gene expression and alternative sp...
RNA sequencing benchmarking across 42 laboratories identifies data quality, sequencing depth, and bioinformatics choices that improve alternative splicing and isoform analysis...
RNA sequencing efforts from the Human RNome Project aim to build a comprehensive reference of human RNA sequences, isoforms, processing states and chemical modifications...
RNA Variant Imaging is attracting attention because it addresses a persistent blind spot in cancer diagnostics: many clinically relevant RNA isoforms, splice events, and fusion tra...
Illumina introduces SpliceAI2, an AI model that improves disease-relevant splice variant prediction, using genomic and RNA sequencing data to demonstrate greater accuracy in identi...
A new framework adapts RNA sequencing analysis for Record-seq, improving spacer extraction, transcription-unit quantification, normalization, differential expression, and modeling...
by Ran Eisenberg, Efraim Rahamim, Eli Kopel, Miri Danan-Gotthold, Erez Y. Levanon, Ofir Lindenbaum Alternative splicing is a fundamental biological mechanism that increases protei...
RNA sequencing combined with qMAP reveals regulatory RNA fragmentation patterns associated with cell reprogramming, ulcerative colitis, implantation failure, and aging...
RiboBA improves ribosome profiling and RNA sequencing analysis by correcting experimental biases, enabling more accurate identification of hidden protein-coding regions and transla...
Malva enables ultrafast, reference-free searches across massive single-cell RNA sequencing datasets for mutations, splice junctions, pathogens, transcripts, and other sequence-leve...
by Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism....
RNAmel integrates RNA sequencing data analysis, gene expression profiling, pathway enrichment and visualization into a reproducible platform that simplifies...
RNA sequencing reveals that calorie restriction drives dose-responsive alternative splicing across multiple tissues, affecting mitochondrial, translational, and RNA quality-control...
Direct RNA sequencing revealed thousands of chimeric mRNAs in mammalian cells, uncovering previously unknown proteins with roles in immunity, inflammation, and potential drug disco...
Small RNA sequencing reveals cell-specific sdRNA patterns in AML and healthy hematopoiesis, linking certain snoRNA-derived RNAs to gene regulation and poorer patient outcomes...
RNA sequencing reveals two opposing patterns of brain gene activity across genetically diverse autism-risk mouse models, with differences...
Eclipsebio’s eSTRAND RNA QC uses direct RNA sequencing to measure multiple RNA quality attributes, including identity, poly(A) tails...
RNA sequencing with Therna’s Chronos platform measures millions of RNA behaviors across diverse human cell types, creating large datasets for modeling expression, stability a...
RNA sequencing comparisons show that short reads can underestimate A-to-I RNA editing, while long-read sequencing provides more accurate measurements through improved genomic align...
ARCADIA integrates single-cell RNA sequencing with spatial proteomics to reveal how tissue neighborhoods influence B-cell maturation, T-cell activation, and other transcriptional p...
Short-read RNA sequencing reporting the modifications that alter protein output is starting to make epitranscriptomics indispensable for patient selection in precision medicines. T...
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