Search results for Aki

A brief kidney crisis in childhood can cast a long shadow over health for years afterward

Acute kidney injury (AKI) is a condition in which the kidneys suddenly lose their ability to filter waste from the blood. Developing within hours or days, AKI can cause dangerous w...

Neonatal Acute Kidney Injury: Diagnosis, Recognition and Prevention

Acute kidney injury (AKI) occurs in around one third of babies treated in a neonatal intensive care unit (NICU). The establishment of consensus standardized definitions has improve...

Independent association between acute kidney injury and kidney function trajectory

It is now universally accepted that acute kidney injury (AKI) is not a limited and entirely reversible condition as many previously thought. However, the independent association be...

in this issue

Several studies have examined whether alerting physicians that a patient has developed acute kidney injury (AKI) can improve AKI outcomes. The results have been conflicting to date...

Electronic AKI alerts at a crossroads: is it time to move on?

Electronic alerts are widely used to identify episodes of acute kidney injury, but evidence for their effectiveness has been conflicting. Xie et al. used real-world data to evaluat...

Machine learning-based prediction of a high-risk kidney function trajectory class after acute kidney injury

Objectives Monitoring kidney function after acute kidney injury (AKI) hospitalisation is essential for identifying patients at risk of rapid progression. This study developed a mac...

Abstract No. LBA17 Histotripsy-induced acute kidney injury following liver tumor treatment: A preliminary report of 8 ca...

To describe eight cases of histotripsy-induced acute kidney injury (HAKI) after treatment of liver tumors.

Consult Rounds: Histotripsy associated AKI

 Histotripsy is an emerging non-invasive, non-thermal ablative technology that uses focused ultrasound pulses to mechanically destroy tumors through acoustic cavitation. Approved b...

SERCA2 deficiency in tubular epithelial cells drives ferroptosis in acute kidney injury regulating endoplasmic reticulum...

Cellular calcium homeostasis is essential for maintaining kidney function. Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2), the primary calcium pump responsible for tr...

HALP Score Links to Outcomes in Acute Kidney Injury

In a groundbreaking retrospective cohort study poised to transform our understanding of acute kidney injury (AKI) prognosis, researchers have unveiled a compelling link between the...

E-selectin Microbubbles Boost Kidney Protection in Rats

Acute kidney injury (AKI) remains one of the most challenging complications faced in clinical settings, often resulting from toxic insults to the kidneys, such as chemotherapy agen...

Revelation Biosciences Announces Formation of Acute Kidney Injury Advisory Board

Therapeutic Efficacy and Antigenicity of a Novel PEGylated IgA Protease in Preclinical Models of IgA Nephropathy

IgA nephropathy is the most common primary glomerulonephritis worldwide, characterized by IgA deposition and a high risk of progression to kidney failure. While emerging therapies...

Akebia Therapeutics, Inc. (AKBA) Discusses Pipeline Progress and Strategic Focus on Kidney Disease Treatments at R&D...

The Kidney in the Middle: KDIGO Guidelines Address Multiple Key Components of Cardiovascular-Kidney-Metabolic Syndrome

Chronic kidney disease (CKD) is closely intertwined with obesity, diabetes, hypertension, dyslipidemia, and cardiovascular disease (CVD). In 2023, the American Heart Association fo...

Estradiol Protects Kidney Tubules Against Ferroptosis

Many studies have shown that male mice and rats are more susceptible to acute kidney injury (AKI) than females (1, 2). In addition, epidemiological studies have supported this sex...

Role of the Post-translational ISGylation of Interferon Regulatory Factor 9 in Diabetes-Induced Podocyte Injury

Diabetic kidney disease (DKD) is the most common cause of kidney failure, with podocyte injury being a key event in its progression. Here, by performing single-cell regulatory netw...

KDIGO updates another IgAN guideline- 2026

 Since the 2025 IgA nephropathy (IgAN) guideline update, three major therapies have reshaped the treatment landscape. Atrasentan, an endothelin A receptor antagonist, received acce...

When normal creatinine hides post-operative kidney injury

The conversation in the surgical ICU happens the same way every time. “His creatinine spiked post-op, but it came back down before discharge. The labs look normal now. The kidney r...

When normal creatinine hides post-operative kidney injury

The conversation in the surgical ICU happens the same way every time. “His creatinine spiked post-op, but it came back down before discharge. The labs look normal now. The kidney r...

Reversal of advanced diabetic kidney disease in mice treated with a monoclonal anti-VEGFR1 antibody

Diabetic kidney disease (DKD) continues to be the major cause of kidney failure, and its treatment is of key importance. Targeting VEGF-A has yielded conflicting results in DKD mod...

3 VASOPRESSOR-INDEXED TIMING OF ERCP AND SURVIVAL IN SEPTIC SHOCK FROM TOKYO GRADE III CHOLANGITIS