Latest updates for Single-Nucleus Transcriptomics...

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Recent items include:

  • Immune cells offer insights on billion-dollar virus
  • Creative Biolabs expands advanced single-cell multi-omics and RNA sequencing solutions to support biomedical discovery
  • CellART extracts single-cell information from high-resolution spatial transcriptomics

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rna-seqblog.com /1 month ago

Immune cells offer insights on billion-dollar virus

Single-nucleus RNA sequencing reveals cell-specific immune responses to white spot syndrome virus in whiteleg shrimp, identifying genes that may support future disease-resistance s...

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rna-seqblog.com /1 month ago

Creative Biolabs expands advanced single-cell multi-omics and RNA sequencing solutions to support biomedical discovery

Creative Biolabs expands RNA sequencing and multi-omics services to profile individual cells and nuclei, supporting biomarker discovery...

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rna-seqblog.com /2 weeks ago

CellART extracts single-cell information from high-resolution spatial transcriptomics

RNA sequencing references combined with CellART help identify individual cells and cell types within high-resolution spatial transcriptomics data across multiple...

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rna-seqblog.com /1 month ago

Single-cell and single-embryo RNA sequencing

Single-cell and single-embryo RNA sequencing enables detailed analysis of gene expression and cell identity during the earliest stages of embryonic development...

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rna-seqblog.com /1 month ago

New method allows scientists to follow gene activity over time in the same cells

Live-cell RNA sequencing uses engineered virus-like particles to repeatedly sample transcriptomes without destroying cells, enabling researchers to track gene expression changes ov...

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rna-seqblog.com /3 weeks ago

Long-read RNA sequencing reveals how neurons choose alternative RNA endings

Long-read RNA sequencing and APALORD reveal how alternative polyadenylation changes during neuronal differentiation and identify new patterns of RNA processing across species...

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journals.plos.org /2 weeks ago

Spatial Transcriptomics As Rasterized Image Tensors (STARIT) characterizes cell states with subcellular molecular hetero...

by Dee Velazquez, Caleb Hallinan, Roujin An, Kalen Clifton, Jean Fan Imaging-based spatially resolved transcriptomics (imSRT) technologies provide high-throughput molecular-resolu...

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rna-seqblog.com /2 weeks ago

GP-DHT uses single-cell RNA sequencing to map gene regulatory networks

Single-cell RNA sequencing combined with GP-DHT helps predict transcription factor and target gene relationships, providing a...

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rna-seqblog.com /2 weeks ago

Tracing 700 million years of cell evolution

RNA sequencing combined with AI helps Unify compare cell types across distant species by identifying shared biological functions even when individual genes no longer directly...

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rna-seqblog.com /1 month ago

ARCADIA combines RNA sequencing and spatial proteomics to reveal how tissue location shapes cell behavior

ARCADIA integrates single-cell RNA sequencing with spatial proteomics to reveal how tissue neighborhoods influence B-cell maturation, T-cell activation, and other transcriptional p...

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rna-seqblog.com /1 month ago

POND-seq enables non-destructive RNA sequencing in living cells

POND-seq enables non-destructive RNA sequencing of living cells, allowing repeated measurement of transcriptomes and RNA-binding protein interactions as cells respond to changing c...

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nanowerk.com /1 month ago

A Google-like search engine for single-cell RNA

Scientists have built a search engine that can scan data from millions of single cells from thousands of experiments worldwide in seconds. The tool makes it possible to answer prev...

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journals.plos.org /1 month ago

Characterization of METTL3/14-mediated m<sup>6</sup>A modification in human transcriptome using Nanopore dir...

by Emily Kurtyan, Andrew J. Stein, Kelly J. Abdalla, Zhangerjiao Yuan, Miten Jain, Fadia Ibrahim Post-transcriptional RNA modifications modulate diverse aspects of RNA metabolism....

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rna-seqblog.com /3 weeks ago

ResolVI improves accuracy in spatial transcriptomics analysis

ResolVI improves spatial RNA sequencing analysis by correcting RNA assignment errors and technical variation, helping researchers distinguish cell states and detect subtle gene exp...

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rna-seqblog.com /1 month ago

New AI approaches to help understand complex biological data

RNA sequencing combined with new AI models helps researchers analyze cellular relationships and biological patterns across scales, improving interpretation of complex single-cell a...

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rna-seqblog.com /1 month ago

Spatial mapping of RNA turnover kinetics in the mouse brain

Spatial RNA sequencing maps RNA synthesis and degradation across the mouse brain, revealing how different regions rapidly adjust gene expression in response to stimulation...

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webwire.com /1 month ago

New method allows scientists to follow gene activity over time in the same cells

The following press release was issued by the Broad Institute of MIT and Harvard. - - In recent years, scientists have built methods to measure a cell's transcriptome, or all t...

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genengnews.com /1 month ago

Single-Cell Striatum Atlas Reveals Neurological Disorder Vulnerabilities

Researchers generated a single-cell atlas of the striatum, identifying 31 neuronal subpopulations and disease-linked vulnerabilities that could inform studies of Huntington’s disea...

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rna-seqblog.com /1 month ago

Autism-risk mutations reveal two opposing patterns of brain gene activity

RNA sequencing reveals two opposing patterns of brain gene activity across genetically diverse autism-risk mouse models, with differences...

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journals.plos.org /3 weeks ago

Integrating zero-inflation correction and transcriptional kinetics for single-cell transcriptomic analysis

by Chengkai Yang, Yu Liao, Ying Sheng, Feng Jiao Single-cell transcriptomic data exhibit pervasive zero inflation, while traditional models either neglect this issue or fail to ca...

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rna-seqblog.com /4 weeks ago

RNA variant imaging for cancer diagnosis

RNA Variant Imaging is attracting attention because it addresses a persistent blind spot in cancer diagnostics: many clinically relevant RNA isoforms, splice events, and fusion tra...

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rna-seqblog.com /1 month ago

A real-data approach to evaluating RNA transcript analysis methods

RNA sequencing data provide a real-world framework for comparing differential transcript usage methods across bulk, single-cell, spatial, long-read, and short-read transcriptomics....

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journals.plos.org /6 days ago

Computational deconvolution of drug sensitivity via single-cell–to–bulk transcriptome mapping

by Alexandre Coudray, Romain Forey, Benjamin Bejar Haro, Filipe Martins, Joana Carlevaro-Fita, Shaoline Sheppard, Sandra Eloise Offner, Gioele La Manno, Guillaume Obozinski, Didier...

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rna-seqblog.com /1 month ago

SPIDER improves spatial transcriptomics data using single-cell RNA sequencing

SPIDER uses single-cell RNA sequencing references to reduce noise in spatial transcriptomics, improving gene expression patterns, tissue structure identification...

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